Results 121 to 130 of about 174,380 (258)
Quantum mechanics/molecular mechanics studies on the mechanism of action of cofactor pyridoxal 5'-phosphate in ornithine 4,5-aminomutase [PDF]
A computational study was performed on the experimentally elusive cyclisation step in the cofactor pyridoxal 5′-phosphate (PLP)-dependent D-ornithine 4,5-aminomutase (OAM)-catalysed reaction.
Anandakrishnan +83 more
core +1 more source
Auricularia auricula polysaccharides (AAP; 100, 200, and 400 mg/kg) protect against acute lung injury (ALI) by dose‐dependently remodeling the gut microbiota and modulating associated metabolic pathways via the gut‐lung axis, thereby enhancing pulmonary anti‐inflammatory and antioxidant capacity to ultimately prevent tissue damage.
Haili Niu +8 more
wiley +1 more source
Assessment of Metabolites in Noni Fruit Slurry Fermented With Four Non‐Saccharomyces Yeasts
Dried noni fruit slurry (DNFS) was fermented for 14 days with selected non‐Saccharomyces yeasts. GCMS, HPLC and amino acid analysis showed that Pichia kluyveri Frootzen and Williopsis saturnus NCYC22 grew well, reduced off‐flavor fatty acids, generated fruity aroma compounds and preserved total phenolic content. ABSTRACT Noni products often suffer from
Zhuoran Zhang, Shao Quan Liu, Yuyun Lu
wiley +1 more source
Molecular mechanisms associated with rootstock–scion interactions in rubber trees
Abstract Hevea brasiliensis (rubber tree) is the main source of natural rubber worldwide. In commercial plantations, high‐yield rubber tree clones are propagated by grafting onto seedling rootstocks. In this study, the transcriptomes of the RRIM 600 clone grafted on different rootstocks in southeastern Brazil were evaluated. Exclusively expressed genes
Wanderson Lima Cunha +11 more
wiley +1 more source
Hermetia illucens larvae meal (HIL) improved broiler growth, carcass yield, gut microbiology, and profitability, with the highest performance observed at 12% inclusion. However, lower inclusion levels (4%) offered a better balance by enhancing meat quality and maintaining favourable fatty acid profiles while still supporting productive and economic ...
Sonia Tabasum Ahmed +4 more
wiley +1 more source
Background The vitamins are important cofactors in various enzymatic-reactions. In past, many inhibitors have been designed against vitamin binding pockets in order to inhibit vitamin-protein interactions.
Panwar Bharat +2 more
doaj +1 more source
Summary Plants orchestrate their developmental processes and responses to environmental stimuli through a sophisticated network of small signaling molecules, termed phytohormones. Among these, auxins are recognized for their role in promoting plant growth.
José Moya‐Cuevas +8 more
wiley +1 more source
Harnessing Photoenzymatic Systems for Intermolecular C–H Fluorination
Despite the remarkable versatility of enzymes for catalyzing complex organic transformations under mild aqueous conditions, no biocatalytic system has been reported for intermolecular C–H fluorination. A radical photoenzymatic approach is introduced that leverages a designed de novo protein scaffold with an unnatural amino acid to achieve precise ...
Yu Zhou +7 more
wiley +2 more sources
Modification of Leucine Dehydrogenase by Pyridoxal 5′-Phosphate
Leucine dehydrogenase (EC 1.4.1.9) from Bacillus sphaericus was inactivated by pyridoxal 5ʹ-phosphate, although less than 50% by one treatment. The inactivation was pH-dependent; the enzyme was most easily inactivated at pH 8.0. The inactivation was reversible by dialysis of the inactivated enzyme, but became irreversible when the inactivation was ...
Toshihisa OHSHIMA, Kenji SODA
openaire +2 more sources
Stroke is a neurological impairment caused by vascular injury of the central nervous system, and globally, stroke is ranked as the second most common cause of death and disability. Numerous risk factors, disease processes, and mechanisms can contribute to stroke, which is not a single disease. G.
Ali Ikram +6 more
wiley +1 more source

