Results 131 to 140 of about 174,380 (258)

Influence of Kynurenine, Neopterin, Noradrenaline and Pyridoxal-5-Phosphate on Cholesterol and Phospholipid Content and Phospholipid Biosynthesis in vitro

Pteridines, 1993
Incorporation of fatty acids into phospholipids has been investigated using samples of rat liver tissue homogenate, Krebs-Ringer-phosphate buffer (pH = 7.4) containing 0.3% albumin, fatty acid mixture and glyceroL The addition of L-kynurenine (4 nmol/g ...
Rudzite Vera, Jurika Edite, Reibnegger Gilbert, Weiss Günter, Wachter Helmut, Fuchs Dietmar   +5 more
doaj   +1 more source

1H‐Nuclear Magnetic Resonance Metabolic Profiling of Pantaneiro and Curraleiro Beef Breeds: Unveiling Adaptation Mechanisms in Brazilian Livestock

New Zealand Journal of Agricultural Research, Volume 69, Issue 1, February 2026.
This study provides the first metabolomic characterization of serum from Pantaneiro and Curraleiro beef cattle, unveiling their unique adaptations to the Pantanal and Cerrado biomes of Brazil. Blood was collected during the summer season to capture metabolic responses to extreme environmental conditions, including high temperatures and varying humidity.
Eduardo Solano Pina dos Santos, Vinicius Laerte Silva Herreira, Ana Laura dos Santos Munhoz Gôngora, Gabriel Henrique Ribeiro, Luiz Alberto Colnago, Brenda Santos de Oliveira, Fernanda Maria Marins Ocampos, Alanne Tenório Nunes, Yasmin Gonçalves da Silva de Souza, Rafael Henrique de Tonissi e Buschinelli de Góes, Yash Dixit, Marlon Martins Reis, Nara Regina Brandão Cônsolo   +12 more
wiley   +1 more source

Plasma Pyridoxal 5´-Phosphate Level in Children with Intractable and Controlled Epilepsy [PDF]

Objective Intractable epilepsy is a serious neurologic problem with different etiologies. Decreased levels of pyridoxal phosphate in cerebral spinal fluid of patients with intractable epilepsy due to pyridoxine dependency epilepsy are reported.
Ghofrani, Mohammad, Mollamohammadi, Mohsen, Pirzadeh, Zahra   +2 more
core  

Effect of pyridoxal phosphate on the DNA binding site of activated hepatic glucocorticoid receptor [PDF]

, 1978
The binding of rat liver glucocorticoid.receptor complexes to DNA-cellulose and nuclei has been studied after activation of the complexes by heating. Subsequent exposure to pyridoxal 5'-phosphate or pyridoxal markedly inhibited this binding.
Cake, M.H., Di Sorbo, D.M., Litwack, G.
core  

Association Between Habitual Food Intake and Energy Metabolism‐Related Urine Metabolites in Female Soccer Players

Molecular Nutrition &Food Research, Volume 70, Issue 3, 13 February 2026.
We studied the relationship between nutrient intake and substances found in urine, both involved in energy production, in female soccer players. We assessed the players' usual diet before the season and collected urine samples before and after matches.
Maria B. A. Nascimento, Maria M. S. Gouveia, Maryssa P. P. Dos Santos, Alessandre C. Crispim, Edmilson R. Da Rocha‐Júnior, Edson S. Bento, Thiago M. Aquino, Nassib B. Bueno, Filipe A. B. Sousa, Gustavo G. De araújo, Thays Ataide‐Silva   +10 more
wiley   +1 more source

Age-related increase of kynurenic acid in human cerebrospinal fluid-IgG and beta(2)-microglobulin changes [PDF]

, 2005
Kynurenic acid (KYNA) is an endogenous metabolite in the kynurenine pathway of tryptophan degradation and is an antagonist at the glycine site of the N-methyl-D-aspartate as well as at the alpha 7 nicotinic cholinergic receptors. In the brain tissue KYNA
Baran, H, Ferraz-Leite, H, Kainz, A, Kalina, P, Kepplinger, B, Newcombe, J   +5 more
core  

Investigating operational stability and causes of cofactor release in fold type I amine transaminase

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Amine transaminases (ATAs) are pyridoxal phosphate (PLP) dependent biocatalysts frequently employed in chiral amine synthesis. Yields of ATA‐catalyzed reactions often suffer from low enzyme operational stability due to weak interactions between the ATA and the aminated cofactor pyridoxamine phosphate (PMP), which can leak from the active site ...
Xuebin Feng, William Chau, Emma R. Master   +2 more
wiley   +1 more source

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

Aging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá, Rosario Ortolá, Mercedes Sotos‐Prieto, Fernando Rodríguez‐Artalejo, Andrés Moya, Susana Ruiz‐Ruiz   +5 more
wiley   +1 more source

Oxygen needs sulfur, sulfur needs oxygen: a relationship of interdependence

The EMBO Journal
Oxygen and sulfur, both members of the chalcogen group (group 16 elements), play fundamental roles in life. Ancient organisms primarily utilized sulfur for energy metabolism, while the rise in atmospheric oxygen facilitated the evolution of aerobic ...
Hiroki Sekine, Takaaki Akaike, Hozumi Motohashi   +2 more
doaj   +1 more source

The Parkinson’s Disease Death Rate: Carbidopa and Vitamin B6 [Retraction]

Clinical Pharmacology: Advances and Applications, 2021
Hinz M, Stein A, Cole T. Clin Pharmacol.  2014;6:161– 169.The Editor-in-chief and Publisher of Clinical Pharmacology: Advances and Applications wish to retract the published article.This perspective article cites several original ...
Hinz M, Stein A, Cole T
doaj