Results 1 to 10 of about 38,650 (260)

Enzyme-independent catabolism of cysteine with pyridoxal-5′-phosphate [PDF]

Scientific Reports, 2023
Pyridoxal-5′-phosphate (PLP) is a versatile cofactor that assists in different types of enzymatic reactions. PLP has also been reported to react with substrates and catalyze some of these reactions independent of enzymes.
Prajakatta Mulay, Cindy Chen, Vijay Krishna   +2 more
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Facile immobilization of pyridoxal 5′-phosphate using p-diazobenzoyl-derivatized Sepharose 4B [PDF]

Results in Chemistry, 2023
Pyridoxal 5′-phosphate (PLP) is a ubiquitous and versatile cofactor utilized by numerous enzymes involved in amino acid biosynthetic pathways. Immobilized PLP is a valuable tool to isolate unknown PLP-dependent enzymes in nature or to perform in vitro ...
Kun-Hwa Lee, Mark D. Distefano, Burckhard Seelig   +2 more
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SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation [PDF]

Nature Communications
Many essential proteins require pyridoxal 5’-phosphate, the active form of vitamin B6, as a cofactor for their activity. These include enzymes important for amino acid metabolism, one-carbon metabolism, polyamine synthesis, erythropoiesis, and ...
Izabella A. Pena, Jeffrey S. Shi, Sarah M. Chang, Jason Yang, Samuel Block, Charles H. Adelmann, Heather R. Keys, Preston Ge, Shveta Bathla, Isabella H. Witham, Grzegorz Sienski, Angus C. Nairn, David M. Sabatini, Caroline A. Lewis, Nora Kory, Matthew G. Vander Heiden, Myriam Heiman   +16 more
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Pyridoxal 5′-phosphate alleviates prenatal pyridaben exposure-induced anxiety-like behaviors in offspring [PDF]

Environmental Science and Ecotechnology, 2023
Pyridaben (PY) is a widely used organochlorine acaricide, which can be detected in the peripheral blood of pregnant women. Available evidence suggests that PY has reproductive toxicity.
Xingwang Ding, Ya Wen, Xuan Ma, Yuepei Zhang, Yuting Cheng, Zhaofeng Liu, Weiyue Hu, Yankai Xia   +7 more
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Complexation of Gold(III) with Pyridoxal 5′-Phosphate-Derived Hydrazones in Aqueous Solution [PDF]

Molecules, 2022
Today, complexes of gold(I) and gold(III) are recognized as promising drugs for the treatment of bacterial infectious diseases and oncological diseases, respectively.
Natalia N. Kuranova, Daniil N. Yarullin, Maksim N. Zavalishin, George A. Gamov   +3 more
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Association of pyridoxal 5′-phosphate (PLP) with lipid profiles: a population-based cohort study [PDF]

Frontiers in Nutrition
ObjectivesThis study aims to explore the correlation between Pyridoxal 5′-Phosphate (PLP) levels and lipid profiles in adult individuals, utilizing data from the National Health and Nutrition Examination Survey (NHANES) database.MethodsThe research ...
Ru-yang Zhang, Yue Chen, Xin-Qi Yan, Yue Zhang, Hua Zhou, Qian Feng   +5 more
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Case report: Hepatocellular carcinoma in a patient with Pyridoxamine 5-phosphate oxidase (PNPO) deficiency undergoing pyridoxal 5-phosphate (PLP) treatment [PDF]

Molecular Genetics and Metabolism Reports
Pyridoxamine 5-phosphate oxidase (PNPO) deficiency is an autosomal recessive inborn error of metabolism that typically manifests as seizures resistant to conventional anticonvulsants, often presenting in the neonatal period to early infancy.
Jesse Zhen Cheng Lee, Chit Kwong Chow, Cheuk-Wing Fung, Stephen Tak Yau Lui, Suet-Na Sheila Wong   +4 more
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yggS Encoding Pyridoxal 5′-Phosphate Binding Protein Is Required for Acidovorax citrulli Virulence [PDF]

Frontiers in Microbiology, 2022
Bacterial fruit blotch, caused by seed-borne pathogen Acidovorax citrulli, poses a serious threat to the production of cucurbits globally. Although the disease can cause substantial economic losses, limited information is available about the molecular ...
Yuanjie Wang, Yuqiang Zhao, Liming Xia, Lin Chen, Yajie Liao, Baohui Chen, Yiyang Liu, Weirong Gong, Yanli Tian, Baishi Hu   +9 more
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Purine limitation prevents the exogenous pyridoxal 5′-phosphate accumulation of Salmonella enterica yggS mutants [PDF]

Microbiology Spectrum
YggS belongs to the highly conserved pyridoxal 5′-phosphate (PLP) binding protein family (COG0325) that is found in all domains of life. Though no precise biochemical activity or molecular mechanism has been determined for this protein, an involvement in
Kailey S. Ezekiel, Diana M. Downs
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Native Microbiome Members of C. elegans Act Synergistically in Biosynthesis of Pyridoxal 5′-Phosphate [PDF]

Metabolites, 2022
The roles of the healthy microbiome on the host and the relationships between members of the microbiome remain to be fully characterized. Due to the complexity of the interactions between the mammalian microbiome and its host, the use of model organisms ...
Orçun Haçariz, Charles Viau, Xue Gu, Jianguo Xia   +3 more
doaj   +2 more sources