Results 101 to 110 of about 150,374 (260)

The Influence of Ethanolic Extract of Hypericum Perforatum (St. John's wort) on Growth Performance, Serum Metabolites, Fat Deposition, Immunity, and Lipid Peroxidation in Broiler Chickens

open access: yesVeterinary Medicine and Science, Volume 11, Issue 5, September 2025.
ABSTRACT Background Having bioactive components such as hypericin, hyperforin and quercetin has enabled Hypericum perforatum (HP) to show antioxidant, antiviral and hypocholesterolemic effects in different animal species. Objectives This study aimed to investigate the effects of different levels of Hypericum perforatum extract (HPE) additions on ...
Mohammad Ali Behroozilak   +4 more
wiley   +1 more source

Hydrogen Sulfide Protects Erectile Function Through Stimulation of Antioxidant Defense in the Corpus Cavernosum: Insights From SG1002 Administration and Cystathionine γ‐Lyase Knockout

open access: yesThe FASEB Journal, Volume 39, Issue 15, 15 August 2025.
Chronic consumption of a western diet suppressed corpus cavernosum cystathionine γ‐lyase (CSE) protein content and H2S production and was associated with elevated penile reactive oxygen species (ROS) levels and impaired erectile function. CSE knockout mice demonstrate impaired erectile function, elevated penile ROS levels, and suppressed corpus ...
Tooyib A. Azeez   +4 more
wiley   +1 more source

Features and Prognosis of Patients With Retroperitoneal Fibrosis Developing Fibrosing Mediastinitis: Case‐Control Study and Systematic Review

open access: yesACR Open Rheumatology, Volume 7, Issue 8, August 2025.
Objective Retroperitoneal fibrosis (RPF) complicated by mediastinal fibrosis (MF) is rare but fatal. We aimed to explore the features and indicators of poor prognosis for the population of those affected. Methods Patients with idiopathic RPF were recruited in Peking University International Hospital.
Yishan Ding   +8 more
wiley   +1 more source

The Parkinson’s Disease Death Rate: Carbidopa and Vitamin B6 [Retraction]

open access: yesClinical Pharmacology: Advances and Applications, 2021
Hinz M, Stein A, Cole T. Clin Pharmacol.  2014;6:161– 169.The Editor-in-chief and Publisher of Clinical Pharmacology: Advances and Applications wish to retract the published article.This perspective article cites several original ...
Hinz M, Stein A, Cole T
doaj  

L-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5′-phosphate-thiazolidine adduct

open access: yes, 2012
Serine palmitoyltransferase (SPT) catalyses the first committed step of de novo sphingolipid biosynthesis. The bacterial SPT homologue from Sphingomonas paucimobilis is a homodimeric enzyme that contains an essential pyridoxal-5′-phosphate (PLP) cofactor
J. Lowther   +4 more
semanticscholar   +1 more source

Growth Performance of Atlantic Salmon Smolts Fed Diets Containing Three Levels of a Single Cell Protein, Torula Yeast

open access: yesAquaculture, Fish and Fisheries, Volume 5, Issue 4, August 2025.
The use of alternative proteins ingredients is needed to support aquaculture. Yeast cells, a single cell protein ingredient, can be successfully incorporated into Atlantic salmon diets without affecting growth performance. ABSTRACT Atlantic salmon (Salmo salar) are globally cultured fish that are typically fed high protein and high lipid diets ...
Brian C. Peterson   +3 more
wiley   +1 more source

Three serendipitous pathways in E. coli can bypass a block in pyridoxal‐5′‐phosphate synthesis

open access: yesMolecular Systems Biology, 2010
Bacterial genomes encode hundreds to thousands of enzymes, most of which are specialized for particular functions. However, most enzymes have inefficient promiscuous activities, as well, that generally serve no purpose.
Juhan Kim   +4 more
doaj   +1 more source

Evaluating Effects of Antibiotics Across Preclinical Models of the Human Gastrointestinal Microbiota

open access: yesMicrobiologyOpen, Volume 14, Issue 4, August 2025.
We compared microbiota changes following antibiotic treatment in two preclinical models of the human GI microbiota, minibioreactor arrays (MBRAs) and human microbiota associated mice (HMAmice). MBRAs and HMAmice were colonized with feces from 12 or 3 healthy humans, respectively, before treatment with each of 12 or 6 antibiotics.
Thomas A. Auchtung   +3 more
wiley   +1 more source

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