Results 211 to 220 of about 150,374 (260)
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Acetylcholinesterase is not inhibited by pyridoxal 5′-phosphate
Biochimica et Biophysica Acta (BBA) - General Subjects, 1986Acetylcholinesterase activity was assayed in the absence and presence of pyridoxal 5'-phosphate. If substrate hydrolysis was measured by the pH-stat method, its rate was not significantly affected by pyridoxal 5'-phosphate. In the spectrophotometric assay, however, this compound led to an apparent decrease in rate.
R. Gentinetta, Urs Brodbeck
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Spectrophotometric determination of pyridoxal-5-phosphate
Analytica Chimica Acta, 1959Abstract A simple and specific spectrophotometric procedure for the estimation of pyridoxal-5-phosphate is described, based on the complete disappearance of the absorption maximum at 385 mμ following the incubation with potassium cyanide.
V. Scardi, V. Bonavita
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ChemInform Abstract: REACTION OF PYRIDOXAL 5′‐PHOSPHATE WITH TRIS [PDF]
Chemischer Informationsdienst, 1982 Kinetic and equilibrium studies are presented on the reaction of pyridoxal 5′-phosphate withTris. Upon raising thepH from 7.3 to 9.3 at 25°C, the second-order rate constant increases from 1.05 M−1 s−1 to 3.79 M−1 s−1, whereas the apparent dissociation constant varies from 2 to 8 mM.
Michael Davis +2 more
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Pyridoxal-5′-phosphate and pyridoxal biokinetics in aging Wistar rats
Experimental Gerontology, 1991Biokinetic parameters of plasma pyridoxal-5'-phosphate (PLP) and pyridoxal (PL) disposition were studied in male Wistar rats aged 8 and 27 months kept from weaning on a purified diet containing 250 g casein and 6 mg pyridoxine.HCl per kg. Baseline plasma PLP concentration was lower in the older animals (514 +/- 56 nmol/L for young and 317 +/- 124 nmol ...
Bode, W., Berg, H. van den
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ChemInform Abstract: POLAROGRAPHIC BEHAVIOR OF PYRIDOXAL 5′‐PHOSPHATE
Chemischer Informationsdienst, 1977AbstractIn Wasser‐DMF‐Gemischen verschiedener Zusammensetzung wird die polarographische Reduktion in Abhängigkeit vom pH‐Wert durchgeführt.
M. Cortijo, J. Llor
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Biological role of carbamoyl pyridoxal 5′-phosphate
Comptes Rendus de l'Académie des Sciences - Series III - Sciences de la Vie, 1997A new compound, carbamoyl-pyridoxal 5'-phosphate (C-PLP), was synthetized by condensation of pyridoxal 5'-phosphate (PLP) with KCNO. It may be obtained under certain physiological conditions of pH, temperature and concentration of reagents. Formation and degradation of C-PLP are readily reversible chemical reactions, not involving enzymes, at least in ...
Terzuoli, Lucia +6 more
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Pyridoxal-5'-phosphate (MC-1), a vitamin B6 derivative, inhibits expressed P2X receptors.
Canadian Journal of Physiology and Pharmacology, 2014P2X receptors are cation-permeable ligand-gated ion channels that open in response to the binding of ATP. These receptors are present in many excitable cells, including neurons, striated muscle cells, epithelial cells, and leukocytes.
Olivier Thériault +5 more
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Exploring the pyridoxal 5′‐phosphate‐dependent enzymes
The Chemical Record, 2006AbstractPyridoxal 5′‐phosphate (PLP)‐dependent enzymes represent about 4% of the enzymes classified by the Enzyme Commission. The versatility of PLP in carrying out a large variety of reactions exploiting the electron sink effect of the pyridine ring, the conformational changes accompanying the chemical steps and stabilizing distinct catalytic ...
MOZZARELLI, Andrea, BETTATI, Stefano
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Direct polarographic determination of pyridoxal in the presence of pyridoxal-5-phosphate
Collection of Czechoslovak Chemical Communications, 1962The determination of pyridoxal in the presence of pyridoxal-5-phosphate may be1 based on the difference between the total wave-height obtained at pH about 9, where both substances give a diffusion-controlled wave and that obtained in acid media, where pyridoxal alone shows a kinetic current2.
O. Manoušek, Petr Zuman
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1979
Publisher Summary The immobilization of pyridoxal 5'-phosphate (PLP) and pyridoxal 5'-phosphate-dependent enzymes on Sepharose is described in this chapter. Immobilized derivatives of PLP (pyridoxal 5'-phosphate) may be useful for the purification by the affinity chromatography of enzymes requiring this coenzyme.
Seiichiro Ikeda, Saburo Fukui
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Publisher Summary The immobilization of pyridoxal 5'-phosphate (PLP) and pyridoxal 5'-phosphate-dependent enzymes on Sepharose is described in this chapter. Immobilized derivatives of PLP (pyridoxal 5'-phosphate) may be useful for the purification by the affinity chromatography of enzymes requiring this coenzyme.
Seiichiro Ikeda, Saburo Fukui
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