Results 51 to 60 of about 150,330 (220)

Cloning and Characterization of Pyridoxal Kinase from Geobacillus sp. H6a

open access: yesJournal of Pure and Applied Microbiology, 2022
Pyridoxal kinase encoded by pdxK gene, is the important key enzyme in the salvage pathway of vitamin B6 biosynthesis. The enzyme catalyzes the phosphorylation of the 5′ alcohol groups of free form vitamin B6 into their 5′-phosphate forms that requires ...
Jumnong Pasri   +2 more
doaj   +1 more source

Early‐onset vitamin B6‐dependent epilepsy due to pathogenic PLPBP variants in a premature infant: A case report and review of the literature

open access: yesJIMD Reports, 2021
Vitamin B6‐dependent epilepsies are a heterogeneous group of disorders characterized by decreased availability of the active cofactor pyridoxal‐5′‐phosphate (PLP).
Oliver Heath   +5 more
doaj   +1 more source

Engineering a pyridoxal 5’-phosphate supply for cadaverine production by using Escherichia coli whole-cell biocatalysis

open access: yesScientific Reports, 2015
Although the routes of de novo pyridoxal 5′-phosphate (PLP) biosynthesis have been well described, studies of the engineering of an intracellular PLP supply are limited and the effects of cellular PLP levels on PLP-dependent enzyme-based whole-cell ...
Weichao Ma   +6 more
semanticscholar   +1 more source

Two-Photon Excited Fluorescence of NADH-Alcohol Dehydrogenase Complex in a Mixture with Bacterial Enzymes

open access: yesBiomolecules, 2023
Thorough study of composition and fluorescence properties of a commercial reagent of active equine NAD-dependent alcohol dehydrogenase expressed and purified from E. coli has been carried out. Several experimental methods: spectral- and time-resolved two-
Ioanna A. Gorbunova   +6 more
doaj   +1 more source

Pyridoxal 5 phosphate for neuroleptic-induced tardive dyskinesia.

open access: yesCochrane Database of Systematic Reviews, 2015
BACKGROUND Tardive dyskinesia is a chronic and disabling abnormal movement disorder affecting the muscles of the face, neck, tongue and the limbs. It is a common side effect of long-term antipsychotic medication use in individuals with schizophrenia and ...
A. Adelufosi   +2 more
semanticscholar   +1 more source

Pyridoxal‐5′‐phosphate as a probe for rotational diffusion [PDF]

open access: yesFEBS Letters, 1983
Its usefulness in measuring the slow rotation of proteins and micelles was demonstrated.
Timothy J. Cornish, John W. Ledbetter
openaire   +2 more sources

Glutamate in Pyridoxine-Dependent Epilepsy

open access: yesPediatric Neurology Briefs, 1994
Cerebrospinal fluid levels of glutamate, g-aminobutyric acid, and pyridoxal-5-phosphate examined in a patient with pyridoxine dependency while on and off vitamin B6 treatment are reported from Universitat Munchen, and Universitats-Nervenklinik, Wurzburg,
J Gordon Millichap
doaj   +1 more source

Common Variants at Putative Regulatory Sites of the Tissue Nonspecific Alkaline Phosphatase Gene Influence Circulating Pyridoxal 5'-Phosphate Concentration in Healthy Adults.

open access: yesJournal of NutriLife, 2015
BACKGROUND Vitamin B-6 interconversion enzymes are important for supplying pyridoxal 5'-phosphate (PLP), the co-enzyme form, to tissues. Variants in the genes for these enzymes [tissue nonspecific alkaline phosphatase (ALPL), pyridoxamine 5'-phosphate ...
Tonia C. Carter   +14 more
semanticscholar   +1 more source

GABA Synthesis and Pyridoxine Seizures

open access: yesPediatric Neurology Briefs, 1994
A reduction in pyridoxal-5-phosphate (PLP) dependent enzyme, glutamic acid decarboxylase (GAD),which synthesizes GABA, is reported in a 3 month-old infant with seizures responsive to pyridoxine treated at University of California, Davis.
J Gordon Millichap
doaj   +1 more source

Pyridoxine Responsiveness and PNPO Gene Mutations

open access: yesPediatric Neurology Briefs, 2014
Investigators at University Hospital, Zurich, Switzerland, and multiple centers in Europe and Canada, sequenced the pyridoxal 5-phosphate oxidase (PNPO) gene in 31 patients with pyridoxine-responsive seizures but normal biomarkers for antiquitin ...
J Gordon Millichap, John J Millichap
doaj   +1 more source

Home - About - Disclaimer - Privacy