Results 61 to 70 of about 54,906 (269)

TRANSFER OF PYRIDOXAL 5'-PHOSPHATE FROM ALBUMIN-PYRIDOXAL 5'-PHOSPHATE COMPLEX TO APO-ASPARTATE AMINOTRANSFERASE

open access: yesJournal of Nutritional Science and Vitaminology, 1973
Pyridoxal 5'-phosphate(PLP)is known to combine with bovine serum albumin to form a (1:1) complex which scarcely dissociates, even when subjected to intensive dialysis. When this complex was incubated with apo-aspartate aminotransferase (apoCOT)for an appropriate time and the preincubated mixture then submitted to the usual GOT assay, the appearance of ...
F, Masugi, Y, Sumi, S, Shimizu, S, Fukui
openaire   +3 more sources

A New Synthesis of Pyridoxal-5-phosphate [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1968
Abstract By the hydrolysis of pyridoxal-5-phosphate Schiff bases, pyridoxal-5-phosphate was prepared in a crystalline form without any further purification. Pyridoxal-5-phosphate Schiff bases were prepared in good yields by the phosphorylation of pyridoxal Scruff bases and were easily purified by alkali-acid reprecipitation.
M, Iwanami, T, Numata, M, Murakami
openaire   +2 more sources

Cloning and Characterization of Pyridoxal Kinase from Geobacillus sp. H6a

open access: yesJournal of Pure and Applied Microbiology, 2022
Pyridoxal kinase encoded by pdxK gene, is the important key enzyme in the salvage pathway of vitamin B6 biosynthesis. The enzyme catalyzes the phosphorylation of the 5′ alcohol groups of free form vitamin B6 into their 5′-phosphate forms that requires ...
Jumnong Pasri   +2 more
doaj   +1 more source

Synthesis, Structural Characterization, Cytotoxicity, and Antibacterial Properties of Gold(III) Complexes with Hydrazones Derived from Vitamin B6

open access: yesInorganics
The rise in the number of cancer cases and the dissemination of strains with multiple drug resistance in the world pose a serious threat to public health care and human well-being.
Daria V. Petrova   +5 more
doaj   +1 more source

Pharmaceutical compounding of orphan active ingredients in Belgium : how community and hospital pharmacists can address the needs of patients with rare diseases [PDF]

open access: yes, 2019
Background: Pharmaceutical compounding of orphan active ingredients can offer cost-effective treatment to patients when no other drug product is available for a rare disease or during periods of drug product shortages.
Boussery, Koen   +7 more
core   +2 more sources

The Streptomyces coelicolor small ORF trpM stimulates growth and morphological development and exerts opposite effects on actinorhodin and calcium-dependent antibiotic production [PDF]

open access: yes, 2020
In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many
Alberto Vassallo   +7 more
core   +2 more sources

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

open access: yesAdvanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen   +9 more
wiley   +1 more source

Two-Photon Excited Fluorescence of NADH-Alcohol Dehydrogenase Complex in a Mixture with Bacterial Enzymes

open access: yesBiomolecules, 2023
Thorough study of composition and fluorescence properties of a commercial reagent of active equine NAD-dependent alcohol dehydrogenase expressed and purified from E. coli has been carried out. Several experimental methods: spectral- and time-resolved two-
Ioanna A. Gorbunova   +6 more
doaj   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Early‐onset vitamin B6‐dependent epilepsy due to pathogenic PLPBP variants in a premature infant: A case report and review of the literature

open access: yesJIMD Reports, 2021
Vitamin B6‐dependent epilepsies are a heterogeneous group of disorders characterized by decreased availability of the active cofactor pyridoxal‐5′‐phosphate (PLP).
Oliver Heath   +5 more
doaj   +1 more source

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