Results 111 to 120 of about 661,688 (260)

HR‐MS Analysis of the Covalent Binding of Edaravone to 5‐Formylpyrimidine Bases and a DNA Oligonucleotide Containing a 5‐Formylcytidine Residue

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue 14, 30 July 2025.
ABSTRACT Rationale Edaravone (EDA) is a radical scavenger and an antioxidant drug approved to treat amyotrophic lateral sclerosis and used as a research tool to explore treatment of neurodegenerative diseases and cancers. It is also a reactive agent, known as PMP (1‐phenyl‐3‐methyl‐5‐pyrazolone), used for the analysis of polysaccharides composition ...
Romain Regnault   +5 more
wiley   +1 more source

A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases. [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Hoffarth ER   +9 more
europepmc   +1 more source

Parkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Expression of Concern]

open access: yesClinical Pharmacology: Advances and Applications, 2020
Hinz M, Stein A, Cole T. Clin Pharmacol Adv Appl. 2014;6:189–194. The Editor-in-Chief and Publisher of Clinical Pharmacology: Advances and Applications wish to issue an Expression of Concern for the published article.
Hinz M, Stein A, Cole T
doaj  

The Pyridoxal Phosphate-dependent Oxidative Decarboxylation of Methionine by Peroxidase

open access: hybrid, 1962
Mendel Mazelis   +2 more
openalex   +2 more sources

Pyridoxal 5′-phosphate alleviates prenatal pyridaben exposure-induced anxiety-like behaviors in offspring

open access: yesEnvironmental Science and Ecotechnology, 2023
Pyridaben (PY) is a widely used organochlorine acaricide, which can be detected in the peripheral blood of pregnant women. Available evidence suggests that PY has reproductive toxicity.
Xingwang Ding   +7 more
doaj  

West Syndrome Is an Exceptional Presentation of Pyridoxine- and Pyridoxal Phosphate-Dependent Epilepsy: Data From a French Cohort and Review of the Literature. [PDF]

open access: yesFront Pediatr, 2021
Gibaud M   +15 more
europepmc   +1 more source

Exploring the Stability and Substrate Profile of Transaminase from Silicibacter pomeroyi with Ancestral Sequence Reconstruction

open access: yesChemBioChem, Volume 26, Issue 13, July 11, 2025.
This study describes the successful identification of ancestral sequences N50 and N49, which have a longer half‐life of approximately four and two times the wild‐type Sp‐amine transaminase, respectively.. This approach effectively enhances the thermal stability of the transaminase.
Luyao Zhao   +4 more
wiley   +1 more source

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