Results 111 to 120 of about 404,528 (235)

Hypoxia‐induced vulnerability of the somatosensory nervous system

The Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Structural and Functional Analysis of the Pyridoxal Phosphate Homeostasis Protein YggS from <i>Fusobacterium nucleatum</i>. [PDF]

Molecules, 2022
He S, Chen Y, Wang L, Bai X, Bu T, Zhang J, Lu M, Ha NC, Quan C, Nam KH, Xu Y.   +10 more
europepmc   +1 more source

Alkaline Phosphatase Activity and Pyridoxal Phosphate Concentrations in the Milk of Various Species

, 1992
Because pyridoxal phosphate does not normally cross membranes, it was intriguing that the concentration of pyridoxal phosphate is much higher in goat milk than in human milk. We also noted that, although the total vitamin B-6 concentration of bovine milk
Thomas A. Pauly, Douglas W. Townsend, Pauly, T A, Townsend, Douglas W, Ericson, K L, Karen L. Ericson, Stephen P. Coburn, Coburn, Stephen P., J. Dennis Mahuren, Mahuren, J D   +9 more
core   +1 more source

Assessment of Biochemical Analytes Stability: The Role of Centrifugation and Storage Conditions in the Preanalytical Phase

Analytical Science Advances, Volume 7, Issue 2, December 2026.
Assessing the impact of different preanalytical factors on biochemical analyte concentrations helps to control emerging risks associated with sample handling. In this study, we provide evidence that the stability of serum biochemical analytes was strongly dependent on both storage temperature and duration.
Zivile Jacike, Rugile Skripkauske, Zivile Sauciuniene, Ema Rajackaite, Paulius Kibisa, Vaiva Lesauskaitė, Ingrida Grabauskyte, Gajdová Marie, Ramune Sepetiene   +8 more
wiley   +1 more source

Parkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Expression of Concern]

Clinical Pharmacology: Advances and Applications, 2020
Hinz M, Stein A, Cole T. Clin Pharmacol Adv Appl. 2014;6:189–194. The Editor-in-Chief and Publisher of Clinical Pharmacology: Advances and Applications wish to issue an Expression of Concern for the published article.
Hinz M, Stein A, Cole T
doaj  

Evaluation of an open formula reference diet on California yellowtail (Seriola dorsalis) Broodstock

Journal of the World Aquaculture Society, Volume 57, Issue 5, October 2026.
Abstract The reliable production of marine finfish is contingent on the quantity and quality of the eggs available from the broodstock. Proper broodstock nutrition is critical for maintaining a supply of good quality eggs. Here, we compared an open‐formula reference diet (OFRD; 18 mm pellet) and a commercial broodstock diet (Europa, Skretting; 12 mm ...
Kevin Stuart, Lee A. Fuiman, Mark Drawbridge   +2 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1759-1771, September 2026.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

West Syndrome Is an Exceptional Presentation of Pyridoxine- and Pyridoxal Phosphate-Dependent Epilepsy: Data From a French Cohort and Review of the Literature. [PDF]

Front Pediatr, 2021
Gibaud M, Barth M, Lefranc J, Mention K, Villeneuve N, Schiff M, Maurey H, Barthez MA, Caubel I, Chouchane M, Doummar D, Kossorotoff M, Lamblin MD, Roubertie A, Nabbout R, Van Bogaert P.   +15 more
europepmc   +1 more source

From Planar to Patterned: Structured Boron‐Doped Diamond Electrodes for Electrochemical Sensing

Analysis &Sensing, Volume 6, Issue 5, September 2026.
Structuring transforms boron‐doped diamond (BDD) from a planar electrode into a versatile sensing platform. This mini‐review surveys top‐down and bottom‐up fabrication routes, shows how structural design reshapes electrochemical behavior—enhancing current response, lowering oxidation potentials, and improving selectivity and stability—and then ...
Ghazaleh Kholafazadehastamal, Karolina Schwarzová‐Pecková, Simona Baluchová   +2 more
wiley   +1 more source

Cytotoxic Effects of Medicinal Plant Extracts on HeLa Cells via Redox Imbalance, L‐Arginine Metabolic Reprogramming, and Glycolytic Suppression

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Cancer cells undergo metabolic reprogramming to sustain proliferation, resist apoptosis, and adapt to oxidative stress. In the present study, we comparatively evaluated the anticancer effects of four medicinal plant extracts (Inula helenium, Hypericum alpestre, Rumex obtusifolius, and Alchemilla smirnovii) on HeLa cervical cancer cells, with ...
Mery Kocharyan, Gohar Sevoyan, Hasmik Karapetyan, Anzhela Sargsyan, Mikayel Ginovyan, Nikolay Avtandilyan, Hayarpi Javrushyan   +6 more
wiley   +1 more source