Results 141 to 150 of about 55,337 (248)

Engineering a Synthetic Formatotrophic Yeast With Enhanced Growth Capacity on Formate

Advanced Energy and Sustainability Research, Volume 7, Issue 5, May 2026.
Engineering Yeast for Growth on Formate and Methanol via Serine‐Centered C1 Coupling. By engineering serine metabolism and remodeling the rGly pathway, we rendered yeast growth strictly dependent on formate. This synthetic formatotrophy enables growth on dual‐C1 substrates by channeling formate into the central metabolism via serine deaminases and ...
Shuyuan Guo, Gulikezi Maimaitirexiati, Qiannan Zhang, Zhehao Jin, Kaidi Chen, Tiantian Zou, Xuemei Zhao, Xiangjian Liu, Zhenmin Bai, Dashuang Gao, Xudong Kong, Tao Yu   +11 more
wiley   +1 more source

A Novel Multimodal LC–MS/MS Panel for the Comprehensive Diagnosis of Neurometabolic Disorders in CSF

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Metabolic testing of cerebrospinal fluid (CSF) is essential for early diagnosis of neurometabolic disorders. However, the large number of differential diagnoses, the phenotypic variance within a clinical picture, and the disease rarity complicate targeted metabolic diagnostics.
Stine Christ, Julia Rossmann, Sylvia Richter, Sven Garbade, Glynis Klinke, Nenad Blau, Georg Friedrich Hoffmann, Jürgen Günther Okun, Thomas Opladen   +8 more
wiley   +1 more source

Parkinson’s Disease: Carbidopa, Nausea, and Dyskinesia [Expression of Concern]

Clinical Pharmacology: Advances and Applications, 2020
Hinz M, Stein A, Cole T. Clin Pharmacol Adv Appl. 2014;6:189–194. The Editor-in-Chief and Publisher of Clinical Pharmacology: Advances and Applications wish to issue an Expression of Concern for the published article.
Hinz M, Stein A, Cole T
doaj  

West Syndrome Is an Exceptional Presentation of Pyridoxine- and Pyridoxal Phosphate-Dependent Epilepsy: Data From a French Cohort and Review of the Literature. [PDF]

Front Pediatr, 2021
Gibaud M, Barth M, Lefranc J, Mention K, Villeneuve N, Schiff M, Maurey H, Barthez MA, Caubel I, Chouchane M, Doummar D, Kossorotoff M, Lamblin MD, Roubertie A, Nabbout R, Van Bogaert P.   +15 more
europepmc   +1 more source

Determination of digestible indispensable amino acid score for salmon hydrolysate proteins

Journal of the Science of Food and Agriculture, Volume 106, Issue 7, Page 4295-4301, May 2026.
Abstract BACKGROUND Salmon products are excellent foods that contain indispensable nutrients including fatty acids and amino acids (AA), but during processing, salmon co‐products that cannot be used for the primary purpose are also generated. Examples of such co‐products include salmon protein hydrolysate concentrate (SPHC) and salmon protein ...
Natalia S Fanelli, Juliana CFR Martins, Hans H Stein   +2 more
wiley   +1 more source

Epilepsy due to PNPO mutations: genotype, environment and treatment affect presentation and outcome [PDF]

, 2017
Mutations in PNPO are a known cause of neonatal onset seizures that are resistant to pyridoxine but responsive to pyridoxal phosphate (PLP). Mills etal. show that PNPO mutations can also cause neonatal onset seizures that respond to pyridoxine but worsen
Bala, Pronab, Baumgartner, Matthias R., Calvert, Sophie, Camuzeaux, Stephane S.M., Chong, W. Kling, Clayton, Peter T., Das, Krishna B., Del Giudice, Ennio, Feillet, François, Fisher, Laura, Footitt, Emma J., Gissen, Paul, Livingston, John H., Maier, Oliver, McWilliam, Robert, Mills, Kevin A., Mills, Philippa B., Morel, Chantal F., Pitt, Matthew, Plecko, Barbara, Raimondi, Francesco, Riney, Kate, Stödberg, Tommy, Varadkar, Sophia M., Wolf, Nicole I., Zuberi, Sameer   +25 more
core  

The Effect of Adding Mountain Mint (Ziziphora clinopodioides Lam.) to Diet of Laying Japanese Quails on Productive Performance, Egg Quality Traits, Blood Metabolites and Immune Response

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Adding mountain mint (Ziziphora clinopodioides Lam.) to diet of laying quails resulted in the production of elongated eggs, improved blood lipid profiles and immune responses. ABSTRACT Background Mountain mint (MM), a traditional herbal remedy, has garnered attention for its potential benefits on poultry health and productivity.
Ahmad Hassanabadi, Mojtaba Teymoori Oghaz, Heydar Zarghi   +2 more
wiley   +1 more source

Structure and function of proteins and nucleic acid Progress report, 1 Jul. - 31 Dec. 1967 [PDF]

Conformation of pyridine nucleotide coenzymes by rotary dispersion and ...
Stryer, L.
core   +1 more source

Modification of Pepsinogen with Pyridoxal Phosphate

Journal of Biological Chemistry, 1974
Pyridoxal-PO4 binds to pepsinogen in a reaction in which the stoichiometry is highly dependent on the conformation of the protein. When pepsinogen is in its native conformation, pyridoxal-PO4 forms Schiff bases with the α-NH2 group of Leu1 and the e-NH2 group of Lys358.
openaire   +2 more sources

Mapping the effects of specific radiation damage and solvent radiolysis in buffers and crystals with online UV–Vis absorption spectroscopy

Acta Crystallographica Section D, Volume 82, Issue 5, Page 504-515, May 2026.
Radiation‐induced changes during X‐ray crystallographic data collection can compromise concurrent spectroscopic studies. Suitable protocols to detect and identify spectral artefacts from crystallization buffers and cryoprotectants are essential for the reliable analysis of chromophoric ligands in macromolecules.Online UV–Vis absorption spectroscopy is ...
Jack Stubbs, Nicolas Caramello, Matthew J. Rodrigues, Sylvain Engilberge, Eric Mathieu, Samuel L. Rose, Gwyndaf Evans, Antoine Royant, Ivo Tews   +8 more
wiley   +1 more source