Results 151 to 160 of about 39,888 (206)

Modern Analytical Techniques in Epilepsy Research. [PDF]

open access: yesInt J Mol Sci
Idzikowska K   +2 more
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Fluorometric assay of pyridoxal and pyridoxal 5′-phosphate

Analytical Biochemistry, 1979
Abstract A new and very sensitive fluorometric method for the determination of pyridoxal and pyridoxal 5′-phosphate is reported. The specificity is based on the reductive amination of pyridoxal and its 5′-phosphate with methyl anthranilate and sodium cyanoborohydride at pH 4,5 to 5,0.
M S, Chauhan, K, Dakshinamurti
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Inhibition of gaba binding by pyridoxal and pyridoxal phosphate

International Journal of Biochemistry, 1980
Abstract 1. 1. GABA exerts its neuroinhibitory effects by binding to a specific receptor on the post-synaptic membrane. 2. 2. Since both GABA and vitamin B 6 have been implicated in convulsion, the effects of B 6 vitamers on Na-independent binding of GABA was investigated by incubating synaptic membrane suspensions for 5 min at 4°C in 1 ml ...
M, Ebadi, B, Klangkalya, J D, Deupree
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DRUG-PYRIDOXAL PHOSPHATE INTERACTIONS

Drug Metabolism and Drug Interactions, 1982
In this review it has been pointed out that vitamin B6 and its vitamers can be involved in many interactions with a number of drugs, as well as with the actions of various endocrines and neurotransmitters. Nutritional deficiencies, especially of vitamins and proteins, can affect the manner in which drugs undergo biotransformation, and thereby may also ...
M, Ebadi, C F, Gessert, A, Al-Sayegh
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The interactions between biogenic amines and pyridoxal, pyridoxal phosphate, and pyridoxal kinase

Archives of Biochemistry and Biophysics, 1972
Abstract The effect of biogenic amines on pyridoxal kinase activity has been investigated in vitro . Experiments with a purified beef brain pyridoxal kinase indicate that 3,4-dihydroxyphenylalanine (dopa), dopamine, norepinephrine, and serotonin inhibit the reaction, while tyrosine, tryptophan, and 5-hydroxytryptophan (5-HTP) have no effect. However,
J T, Neary   +3 more
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Pyridoxal-5′-phosphate and pyridoxal biokinetics in aging Wistar rats

Experimental Gerontology, 1991
Biokinetic parameters of plasma pyridoxal-5'-phosphate (PLP) and pyridoxal (PL) disposition were studied in male Wistar rats aged 8 and 27 months kept from weaning on a purified diet containing 250 g casein and 6 mg pyridoxine.HCl per kg. Baseline plasma PLP concentration was lower in the older animals (514 +/- 56 nmol/L for young and 317 +/- 124 nmol ...
Bode, W., Berg, H. van den
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Transport and Metabolism of Pyridoxal and Pyridoxal Phosphate in the Small Intestine of the Rat

The Journal of Nutrition, 1979
The vascularly perfused small intestine of the rat was utilized to study the absorption and metabolism of pyridoxamine (PM) and pyridoxamine-5'-phosphate (PMP), independent of other tissues including erythrocytes. [3H]PM or [3H]PMP was administered intralumenally with or without the addition of unlabeled PM, or PMP or inorganic phosphate.
H, Mehansho, M W, Hamm, L M, Henderson
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