Results 1 to 10 of about 85,442 (189)
BioMed Research International, 2014 The main focus of this special issue is on structural, functional, and biomedical studies on pyridoxal-5′-phosphate- (PLP-) dependent enzymes. The unparalleled catalytic versatility of PLP, the active form of vitamin B6, originates from its unique electron-sinking properties, which stabilize reaction intermediates, thus lowering the activation barrier ...
Paiardini A. +3 more
openaire +5 more sources
Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse [PDF]
, 2012 Mice overexpressing proteolipid protein (PLP) develop a leukodystrophy-like disease involving cytotoxic, CD8+ T-lymphocytes. Here we show that these cytotoxic T-lymphocytes perturb retrograde axonal transport.
Antje Kroner +11 more
core +6 more sources
Characterization of Plp, a phosphatidylcholine-specific phospholipase and hemolysin of Vibrio anguillarum [PDF]
, 2014 Background: Vibrio anguillarum is the causative agent of vibriosis in fish. Several extracellular proteins secreted by V. anguillarum have been shown to contribute to virulence.
Li, Ling, Mou, Xiangyu, Nelson, David R
core +6 more sources
Protective role of vitamin B6 (PLP) against DNA damage in Drosophila models of type 2 diabetes [PDF]
, 2018 Growing evidence shows that improper intake of vitamin B6 increases cancer risk and several studies indicate that diabetic patients have a higher risk of developing tumors.
MF Fenech +69 more
core +2 more sources
PLP-dependent H2S biogenesis [PDF]
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2011 The role of endogenously produced H(2)S in mediating varied physiological effects in mammals has spurred enormous recent interest in understanding its biology and in exploiting its pharmacological potential. In these early days in the field of H(2)S signaling, large gaps exist in our understanding of its biological targets, its mechanisms of action and
Sangita, Singh, Ruma, Banerjee
openaire +2 more sources
Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]
, 2013 NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H +4 more
core +2 more sources
A Myelin Proteolipid Protein-LacZ Fusion Protein Is Developmentally Regulated and Targeted to the Myelin Membrane in Transgenic Mice [PDF]
, 1993 Transgenic mice were generated with a fusion gene carrying a portion of the murine myelin proteolipid protein (PLP) gene, including the first intron, fused to the E. coli LacZ gene.
Duchala, Cynthia S. +3 more
core +2 more sources
WORKSHOP BIMBINGAN PENGALAMAN LAPANGAN PERSEKOLAHAN PLP
Community Development Journal : Jurnal Pengabdian Masyarakat, 2022 Sesuai dengan standar pendidikan guru bahwa mahasiswa program sarjana kependidikan harus mengikuti mata kuliah pengenalan lapangan persekolahan di satuan pendidikan. Untuk mencapai tujuan Pelaksanaan PLP tersebut perlu di dukung oleh pembimbing dari unsur guru yang memahami secara teknis pembimbingan dan evaluasi mahasiswa peserta PLP, juga agar dapat
Safrudin, Safrudin +3 more
openaire +2 more sources
Motor correlates of phantom limb pain [PDF]
, 2017 Following amputation, individuals ubiquitously report experiencing lingering sensations of their missing limb. While phantom sensations can be innocuous, they are often manifested as painful.
Henderson Slater, D +5 more
core +2 more sources
Sugar and chromosome stability: Clastogenic effects of sugars in vitamin B6-deficient cells [PDF]
, 2014 Pyridoxal 5'-phosphate (PLP), the active form of vitamin B6, has been implicated in preventing human pathologies, such as diabetes and cancer. However, the mechanisms underlying the beneficial effects of PLP are still unclear. Using Drosophila as a model
Gatti, Maurizio +3 more
core +3 more sources