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The main focus of this special issue is on structural, functional, and biomedical studies on pyridoxal-5′-phosphate- (PLP-) dependent enzymes. The unparalleled catalytic versatility of PLP, the active form of vitamin B6, originates from its unique electron-sinking properties, which stabilize reaction intermediates, thus lowering the activation barrier ...
Paiardini A. +3 more
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First report of jackfruit decline caused by Phytophthora spp. in Bangladesh
A survey was conducted at Gazipur, one of the major jackfruit producing districts in Bangladesh where decline syndromes were frequently observed. The characteristic symptoms of jackfruit decline included trunk canker, wilting, dieback of the canopy and ...
Farhana Jenny +2 more
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Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis in Streptococcus pneumoniae [PDF]
Spr1654 from Streptococcus pneumoniae plays a key role in the production of unusual sugars, presumably functioning as a pyridoxal-5′-phosphate (PLP)-dependent aminotransferase. Spr1654 was predicted to catalyse the transferring of amino group to form the
Xiao Han +3 more
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Crystal Structure and Pyridoxal 5-Phosphate Binding Property of Lysine Decarboxylase from Selenomonas ruminantium. [PDF]
Lysine decarboxylase (LDC) is a crucial enzyme for acid stress resistance and is also utilized for the biosynthesis of cadaverine, a promising building block for bio-based polyamides.
Hye-Young Sagong +5 more
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Pyridoxal 5′-phosphate (PLP) is the active form of vitamin B6, but it is highly reactive and poisonous in its free form. YggS is a PLP-binding protein found in bacteria and humans that mediates PLP homeostasis by delivering PLP to target enzymes or by ...
Shanru He +10 more
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Enzyme-independent catabolism of cysteine with pyridoxal-5′-phosphate
Pyridoxal-5′-phosphate (PLP) is a versatile cofactor that assists in different types of enzymatic reactions. PLP has also been reported to react with substrates and catalyze some of these reactions independent of enzymes.
Prajakatta Mulay +2 more
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This paper implements the continuous Hindi Automatic Speech Recognition (ASR) system using the proposed integrated features vector with Recurrent Neural Network (RNN) based Language Modeling (LM).
Kumar A., Aggarwal R.K.
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A synthetic peptide, K-PLP, consisting of 11-unit poly-lysine (K11) linked via polyethylene glycol (PEG) to proteolipid protein epitope (PLP) was synthesized, characterized, and evaluated for efficacy in ameliorating experimental autoimmune ...
Jimmy Y. Song +8 more
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Scaling the performance of shared-everything transaction processing systems to highly-parallel multicore hardware remains a challenge for database system designers. Recent proposals alleviate locking and logging bottlenecks in the system, leaving page latching as the next potential problem.
Ippokratis Pandis +3 more
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The Parkinson’s Disease Death Rate: Carbidopa and Vitamin B6 [Retraction]
Hinz M, Stein A, Cole T. Clin Pharmacol. 2014;6:161– 169.The Editor-in-chief and Publisher of Clinical Pharmacology: Advances and Applications wish to retract the published article.This perspective article cites several original ...
Hinz M, Stein A, Cole T
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