Results 61 to 70 of about 33,290 (259)

Pyridoxine-dependent epilepsy in two Turkish patients in Turkey and review of the literature

open access: yesThe Turkish Journal of Pediatrics, 2015
Pyridoxine-dependent epilepsy (PDE) is a rare autosomal recessive enzyme defect in the vitamin B6 metabolism characterized by intractable seizures which are usually resistant to all antiepileptic drugs but respond to pharmacological doses of ...
Gülen Gül-Mert   +4 more
doaj  

Effect of Pyridoxine and Different Levels of Nitrogen on Yield and Yield Components of Corn (Zea mays L. Var. SC. 704) [PDF]

open access: yesفیزیولوژی محیطی گیاهی, 2009
A Field experiment was conducted on Corn (Zea mays L. Var. S.C. 704) to study the effect of three basal doses of nitrogen (90, 140, 190 Kg/ha) along with 0.01 and 0.02% pre–sowing seed soaking treatment with pyridoxine for 8 hours.
D Eradatmand Asli   +2 more
doaj  

Effect of the Ascorbic Acid, Pyridoxine and Hydrogen Peroxide Treatments on Germination, Catalase Activity, Protein and Malondialdehyde Content of Three Oil Seeds

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2008
Oil seed production has an important role in human nutrition and industry. Success in oil plant cultivation is related to seed production with high viability and rapid germination, because these seeds rapidly loose their viability by fats oxidation. Thus,
Aria DOLATABADIAN   +1 more
doaj   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Neonatal seizures: Advances in diagnosis and management

open access: yesEpilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz   +2 more
wiley   +1 more source

Neuropathology of pyridoxine toxicity [PDF]

open access: yes, 1994
Pyridoxine can cause sensory neuropathy in man. Previous experimental studies have demonstrated selective neurofilament accumulation in dorsal root ganglion cells which, in most cases, was associated with axonal damage without causing cell death, but in ...
Pires, Manuel Melo
core   +1 more source

GCP II inhibition improved several pyridoxine-induced locomotor deficits.

open access: yes, 2014
(a) Walking performance was significantly reduced upon pyridoxine treatment with the control group being significantly different to both pyridoxine treated groups particularly on days 11 and 15.
Barbara S. Slusher (634276)   +3 more
core   +1 more source

The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia   +4 more
wiley   +1 more source

Triggered Calcium Lightning Programs Cochlear Development

open access: yesExploration, EarlyView.
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma   +13 more
wiley   +1 more source

Stage‐Dependent Metabolic Reprogramming Drives a Self‐Organizing Microbial Network During Shanxi Aged Vinegar

open access: yesFood Bioengineering, EarlyView.
Metabolic shifts from growth to stress adaptation in Shanxi aged vinegar fermentation link flavor maturation and microbial cooperation, and Lactobacillus and Acetobacter form a self‐organizing metabolic network through division of labor. ABSTRACT Acetic acid fermentation (AAF) is a vital stage in the production of Shanxi aged vinegar (SAV), during ...
Yanfang Wu   +6 more
wiley   +1 more source

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