Results 91 to 100 of about 3,728 (241)
Caffeine. cognitive and physical performance enhancer or psychoactive drug? [PDF]
, 2015 Caffeine use is increasing worldwide. The underlying motivations are mainly concentration and memory enhancement and physical performance improvement. Coffee and caffeine-containing products affect the cardiovascular system, with their positive inotropic
Aromatario, Mariarosaria +3 more
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Fluids and Barriers of the CNS, 2018 Background para-Tyramine (p-TA) is a biogenic amine which is involved in multiple neuronal signal transductions. Since the concentration of p-TA in dog cerebrospinal fluid (CSF) has been reported to be greater than that in plasma, it is proposed that ...
Shin-ichi Akanuma +3 more
doaj +1 more source
Pharmacological profile of novel psychoactive benzofurans [PDF]
, 2015 Benzofurans are newly used psychoactive substances, but their pharmacology is unknown. The aim of the present study was to pharmacologically characterize benzofurans in vitro.; We assessed the effects of the benzofurans 5-APB, 5-APDB, 6-APB, 6-APDB, 4 ...
Hoener, Marius C. +3 more
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Epigenetic Alterations and an Increased Frequency of Micronuclei in Women with Fibromyalgia [PDF]
, 2013 Fibromyalgia (FM), characterized by chronic widespread pain, fatigue, and cognitive/mood disturbances, leads to reduced workplace productivity and increased healthcare expenses.
Colleen Jackson-Cook +8 more
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Drug Design, Development and Therapy, 2016 Bassem Sadek,1 Ali Saad,1 Gniewomir Latacz,2 Kamil Kuder,2 Agnieszka Olejarz,2 Tadeusz Karcz,2 Holger Stark,3 Katarzyna Kieć-Kononowicz2 1Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates ...
Sadek B +7 more
doaj
Sites of action of sleep and wake drugs: insights from model organisms [PDF]
, 2013 Small molecules have been used since antiquity to regulate our sleep. Despite the explosion of diverse drugs to treat problems of too much or too little sleep, the detailed mechanisms of action and especially the neuronal targets by which these compounds
Rihel, J, Schier, AF
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H(1)-Receptor activation triggers the endogenous nitric oxide signalling system in the rat submandibular gland. [PDF]
, 2002 BACKGROUND: Histamine is released from mast cells by immunologic and non-immunologic stimuli during salivary gland inflammation, regulating salivary secretion. The receptor-secretory mechanism has not been studied in detail.
Borda, Enri +2 more
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Evaluation of In Vitro Uterotonic Activities of Fruit Extracts of Ficus asperifolia in Rats [PDF]
, 2011 The aim of the present study was to determine the uterotonic activities of Ficus asperifolia and investigate its mechanism. The effects of aqueous and methanol extracts of the dried fruits of F.
Alango Nkeng-Efouet, Pepin +4 more
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Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives [PDF]
, 2014 Aminoindanes, piperazines, and pipradrol derivatives are novel psychoactive substances found in "Ecstasy" tablets as replacements for 3,4-methylenedioxymethamphetamine (MDMA) or substances sold as "ivory wave." The pharmacology of these MDMA- and ...
Hoener, Marius C. +4 more
core +1 more source
Vasopeptidase-activated latent ligands of the histamine receptor-1 [PDF]
, 2013 Whether peptidases present in vascular cells can activate prodrugs active on vascular cells has been tested with 2 potential latent ligands of the histamine H1 receptor (H1R). First, a peptide consisting of the antihistamine cetirizine (CTZ) condensed at
Charest-Morin??, Xavier +3 more
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