Results 71 to 80 of about 1,693 (192)
The involvement of histamine H3 receptors (H3Rs) in memory is well known, and the potential of H3R antagonists in therapeutic management of neuropsychiatric diseases, e.g., Alzheimer disease (AD) is well established.
Alaa Alachkar +3 more
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The chances to succeed in goal-directed behaviors, such as food or water-seeking, improve when the subject is in an increased arousal state. The appetitive phase of these motivated behaviors is characterized by high levels of behavioral and vegetative ...
María E. Riveros +6 more
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Neuroimmune interactions: role for cholinergic neurons in intestinal anaphylaxis [PDF]
The role of cholinergic neurons in mediating chloride secretion in anaphylaxis was assessed in muscle-stripped segments of distal colon from guinea pigs immunized to bovine milk.
Y. Z. Wang, N. H. Javed, H. J. Cooke
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Combination Therapies of the Neurotransmitter-Targeting Drugs Dextromethorphan, Pyrilamine and Lorcaserin in a Rat Model of Nicotine Addiction [PDF]
Honors Thesis in Biology: Basis for study to be published in "Neuroscience"Given the current epidemic of nicotine dependence, the study of interactions between neurotransmitter receptor-targeting molecules to discover possible new forms of smoking ...
Briggs, Scott, Scott Alan Briggs
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Histamine responses mediated via H1 and H2−receptors in the isolated portal vein of the dog [PDF]
The effects of histamine were studied on the isolated circular muscle strip and longitudinal muscle strip of the dog portal vein. Histamine-induced contractions of the circular muscle were inhibited by H1-receptor antagonist pyrilamine but increased by ...
Yasuo Shimo +3 more
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Bassem Sadek,1 Ali Saad,1 Gniewomir Latacz,2 Kamil Kuder,2 Agnieszka Olejarz,2 Tadeusz Karcz,2 Holger Stark,3 Katarzyna Kieć-Kononowicz2 1Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates ...
Sadek B +7 more
doaj
Background para-Tyramine (p-TA) is a biogenic amine which is involved in multiple neuronal signal transductions. Since the concentration of p-TA in dog cerebrospinal fluid (CSF) has been reported to be greater than that in plasma, it is proposed that ...
Shin-ichi Akanuma +3 more
doaj +1 more source
Pentagastrin gastroprotection against acid is related to H2 receptor activation but not acid secretion [PDF]
Background—Pentagastrin enhances gastric mucosal defence mechanisms against acid and protects the gastric mucosa from experimental injury.Aims—To investigate whether this gastroprotection is mediated by histamine receptors or occurs as a secondary effect
J D Kaunitz, S Tanaka, Y Akiba
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Endothelium-dependent relaxations to histamine in the rat common carotid, renal and cranial mesenteric artery [PDF]
The effect of histamine on the isolated rat common carotid, renal and cranial mesenteric arteries was examined. Histamine (10-8 - 10-4 m) caused concentration-dependent relaxations of the arteries during contractions induced with phenylephrine (10-8 - 10-
Katušić, Z.S +3 more
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Genetic deficiency of carnitine/organic cation transporter 2 (slc22a5) is associated with altered tissue distribution of its substrate pyrilamine in mice [PDF]
Carnitine/organic cation transporter 2 (OCTN2) recognizes various cationic compounds as substrates in vitro, but information on its pharmacokinetic role in vivo is quite limited.
Kato, Sayaka +6 more
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