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Simultaneous Spectrophotometric Determination of Pyrilamine Maleate and Quinine

Bulletin (Society for Applied Spectroscopy), 1951
The inclusion of the recently developed antihistamines in cold tablets has led to the interesting problem of quantitatively estimating constituents which have very similar chemical and physical properties. Formulations have appeared containing aspirin, caffeine, phenacetin, and quinine hydrobromide in combination with the well established ...
J. D. Neuss   +2 more
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Tablets of Pyrilamine Resin Adsorbate with Aspirin and Vitamin C

Journal of Pharmaceutical Sciences, 1962
Marked changes in physical appearance manifested by dry formulations containing aspirin, an antihistamine, and vitamin C during an accelerated temperature stability study are discussed. The stabilization afforded by a resin adsorbate of a commonly used antihistamine, pyrilamine, is noted.
S, SIEGEL   +3 more
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Effect of Cimetidine and Pyrilamine on Histamine-Induced Ocular Surface Hyperemia

Journal of Ocular Pharmacology and Therapeutics, 1986
Histamine-induced ocular surface redness was virtually abolished by a combination of cimetidine (H2-receptor antagonist) and pyrilamine (H1-receptor antagonist), whereas either antagonist administered alone produced no significant reduction. It appears that combined H1- and H2-antagonist therapy is required for effective blockade of ocular responses to
D F, Woodward   +3 more
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Identification of urinary metabolites of pyrilamine after oral administration to man

Xenobiotica, 1994
1. The metabolism of pyrilamine, 2-[4-methoxybenzyl-(2-dimethylaminoethyl) amino] pyridine, was studied in adult male volunteers after a single oral dose of 50 mg. 2. Solvent extracts of urine obtained with or without enzyme hydrolysis were analysed by gc/ms after derivatization with MSTFA/TMSCI (N-methyl-N-trimethylsilyl-trifluoroacetamide/trimethyl ...
B C, Chung   +5 more
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The General Toxicology Unknown II. A Case Report: Doxylamine and Pyrilamine Intoxication

Journal of Forensic Sciences, 1983
Abstract A general toxicology unknown case is presented to demonstrate our systematic approach. A 20-year-old male was found dead with multiple suicide notes. Overdose was suspected but substances were not known. Blood alcohol was negative.
N B, Wu Chen   +5 more
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[Research progress of pyrilamine-sensitive H~+/OC antiporter].

Yao xue xue bao = Acta pharmaceutica Sinica, 2018
In recent years, a new type of organic cation transporter has been found to transport organic cation drugs like pyrilamine, diphenhydramine and oxycodone in brain capillary endothelial cells, Caco-2 cells and other cells. Its transport activity can not be inhibited by typical organic cation transporter substrates or inhibitors, and its transport ...
Xin-yi, Wang, Zhi-rong, Zhang
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Antihistamine drugs on rat pregnancy: Effects of pyrilamine and meclizine

Life Sciences, 1963
Abstract Pyrilamine administration in the early stages of pregnancy in the rat caused: a) an increase in the frequency of implantation anomalies and b) several toxic effects appearing in the last stages of pregnancy. Meclizine, on the other hand, had virtually no effects.
F. Bovet-Nitti, G. Bignami, D. Bovet
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