Results 201 to 210 of about 3,638 (238)
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Biomedical & environmental mass spectrometry, 1990
Combined high-performance liquid chromatography/thermospray mass spectrometry (HPLC/TSMS) and HPLC/thermospray tandem mass spectrometry (HPLC/TSMS/MS) were utilized for the analysis of rat urine for metabolites of pyrilamine.
Walter A. Korfmacher +4 more
semanticscholar +1 more source
Combined high-performance liquid chromatography/thermospray mass spectrometry (HPLC/TSMS) and HPLC/thermospray tandem mass spectrometry (HPLC/TSMS/MS) were utilized for the analysis of rat urine for metabolites of pyrilamine.
Walter A. Korfmacher +4 more
semanticscholar +1 more source
Effect of Cimetidine and Pyrilamine on Histamine-Induced Ocular Surface Hyperemia
Journal of Ocular Pharmacology and Therapeutics, 1986Histamine-induced ocular surface redness was virtually abolished by a combination of cimetidine (H2-receptor antagonist) and pyrilamine (H1-receptor antagonist), whereas either antagonist administered alone produced no significant reduction. It appears that combined H1- and H2-antagonist therapy is required for effective blockade of ocular responses to
June Chen +3 more
openaire +3 more sources
The General Toxicology Unknown II. A Case Report: Doxylamine and Pyrilamine Intoxication
Journal of Forensic Sciences, 1983Abstract A general toxicology unknown case is presented to demonstrate our systematic approach. A 20-year-old male was found dead with multiple suicide notes. Overdose was suspected but substances were not known. Blood alcohol was negative.
R. L. Lin +5 more
openaire +2 more sources
Antihistamine drugs on rat pregnancy: Effects of pyrilamine and meclizine
Life Sciences, 1963Abstract Pyrilamine administration in the early stages of pregnancy in the rat caused: a) an increase in the frequency of implantation anomalies and b) several toxic effects appearing in the last stages of pregnancy. Meclizine, on the other hand, had virtually no effects.
Bovet-Nitti F +2 more
openaire +2 more sources
Ocular disposition of topically applied histamine, cimetidine, and pyrilamine in the albino rabbit
Current Eye Research, 1984Aqueous solutions of pyrilamine, cimetidine, and histamine were instilled into the eyes of albino rabbits and drug levels determined as a function of time in the cornea, conjunctiva, aqueous humor, and iris-ciliary body. For all three drugs, less than 1% of the applied dose penetrates to the aqueous humor.
Lowell Zeleznick +2 more
openaire +3 more sources
Ascorbate increases apparent “specific” binding of [3H]pyrilamine to glass fiber filters
Journal of Pharmacological Methods, 1988Although filtration through glass fiber filters provides a convenient method for separating bound from unbound radioligand, binding of the ligand to the filters is often a problem. Ascorbate (0.1%) has been shown to decrease binding of serotonergic acids to these filters. In the present study, relatively high binding of [3H]pyrilamine, an H1-antagonist,
Miriam D. Rosenthal +1 more
openaire +3 more sources
A Discussion of Pyrilamine Metabolite Identification [PDF]
Journal of Analytical Toxicology, 1987 openaire +2 more sources
Physical and Biological Properties of Pyrilamine
Journal of Pharmaceutical Sciences, 1983openaire +3 more sources