cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. [PDF]
Blocking Plasmodium falciparum transmission to mosquitoes has been designated a strategic objective in the global agenda of malaria elimination. Transmission is ensured by gametocyte-infected erythrocytes (GIE) that sequester in the bone marrow and at ...
A Dawn +74 more
core +9 more sources
The Risk of Recrystallization: Changes to the Toxicity and Morphology of Pyrimethamine
PURPOSE. Pyrimethamine, an anti-malarial agent known to exhibit solid state polymorphism, may be purified by means of recrystallization. Recrystallization may alter the solid state chemistry of pharmaceuticals, which may impact the toxicity and/or ...
Zak Perold, Mino R Caira, Marius Brits
doaj +1 more source
Ecological comparison of the risks of mother-to-child transmission and clinical manifestations of congenital toxoplasmosis according to prenatal treatment protocol [PDF]
We compared the relative risks of mother-to-child transmission of Toxoplasma gondii and clinical manifestations due to congenital toxoplasmosis associated with intensive prenatal treatment in Lyon and Austria, short term treatment in 51% of Dutch women ...
Dunn, D +9 more
core +2 more sources
Background and purpose: There are few treatment options available for treatment of toxoplasmosis and effective drugs have serious toxic effects. In this study, the in vivo and in vitro anti-toxoplasma activities of Heracleum persicum and Foeniculum ...
Mahbobeh Montazeri +7 more
doaj
Clinical and parasitological response to oral chloroquine and primaquine in uncomplicated human Plasmodium knowlesi infections [PDF]
Background: Plasmodium knowlesi is a cause of symptomatic and potentially fatal infections in humans. There are no studies assessing the detailed parasitological response to treatment of knowlesi malaria infections in man and whether antimalarial ...
Cox Singh, Janet +6 more
core +1 more source
INTRODUCTION: La présente étude prospective se propose d'évaluer l'efficacité thérapeutique du traitement préventif intermittent à la sulfadoxine pyriméthamine et son observance chez la femme enceinte dans deux hôpitaux urbains au Burkina Faso. METHODES:
Sanata Bamba +6 more
doaj +1 more source
MRI and clinical resolution of a suspected intracranial toxoplasma granuloma with medical treatment in a domestic short hair cat [PDF]
A two-year-old cat was presented with a left paradoxical vestibular syndrome. MRI of the brain revealed an extra-axial homogenously contrast enhancing mass in the region of the left caudal cerebellar peduncle.
Beltran, E, Crawford, A H, Drees, R
core +1 more source
Detection of the Resistance of Parasite to Sulfadoxine-pyrimethamine Drugs and msp-2 Genotyping as A Baseline in Developing Malaria Vaccine with Ionizing Radiation [PDF]
Mukh Syaifudin +4 more
openalex +1 more source
Background Sulphadoxine-pyrimethamine, in combination with artesunate or amodiaquine, is recommended for the treatment of uncomplicated malaria and is being evaluated for intermittent preventive treatment.
Doumbo Ogobara K +11 more
doaj +1 more source

