Results 71 to 80 of about 22,882 (212)

Invasive Fungal Infections in Heart Transplants: A 10‐Year, Single Centre Retrospective Cohort Study From Subtropical Australia

Transplant Infectious Disease, EarlyView.
In this 10‐year retrospective cohort study of heart transplant recipients in subtropical Australia, we characterize the incidence and microbiological profile of invasive fungal infections, highlighting the underappreciated burden of late‐onset and non‐Aspergillus mold infections and the potential underdiagnosis of polymicrobial disease.
Angus Lane, Karen Hay, John McNamara, Alex Chaudhuri, Andrew Burke, Robert Horvath, Maryam Khorramshahi Bayat, Kanthi Vemuri   +7 more
wiley   +1 more source

Uncomplicated Malaria in Infancy and Neurodevelopment at 1 and 6 Years: Evidence From the MiPPAD Birth Cohort Study of Benin

Tropical Medicine &International Health, EarlyView.
ABSTRACT In malaria‐endemic regions, repeated episodes of uncomplicated malaria during infancy are common; however, their associations with neurodevelopment remain unclear. We examined relationships between malaria frequency in infancy and neurodevelopmental outcomes in early and middle childhood, using data from the APEC birth cohort nested within the
Juthathip Khongpetch, Michael J. Boivin, Michel Cot, Jacqueline Milet, Roméo Zoumenou, Christophe Fermanian, Achille Massougbodji, Florence Bodeau‐Livinec   +7 more
wiley   +1 more source

Adding artesunate to sulphadoxine-pyrimethamine greatly improves the treatment efficacy in children with uncomplicated falciparum malaria on the coast of Benin, West Africa

Malaria Journal, 2007
Background Benin has recently shifted its national antimalarial drug policy from monotherapies to combinations containing artemisinin derivatives. When this decision was taken, the available information on alternatives to chloroquine and sulphadoxine ...
Coosemans Marc, Akogbeto Martin, Menten Joris, van Loen Harry, Van Overmeir Chantal, Agbowai Carine, Gazard Dorothée, Erhart Annette, Nahum Alain, Massougbodji Achille, D'Alessandro Umberto   +10 more
doaj   +1 more source

Efficacy of amodiaquine, sulphadoxine-pyrimethamine and their combination for the treatment of uncomplicated Plasmodium falciparum malaria in children in Cameroon at the time of policy change to artemisinin-based combination therapy. [PDF]

, 2010
BACKGROUND: The efficacy of amodiaquine (AQ), sulphadoxine-pyrimethamine (SP) and the combination of SP+AQ in the treatment of Cameroonian children with clinical malaria was investigated.
Isabel A Ateh, Ateh Isabel A, Irenee, Domkam, Wilfred F Mbacham, Ateh, Isabel A, Justin B Echouffo-Tcheugui, Cally Roper, Patrice N Mimche, Bantar Tawe, Tawe Bantar, Palmer M Netongo, Hallett, Rachel, Evehe Marie-Solange B, Rachel Hallett, Nji Akindeh M, Evehe, Marie-Solange B, Mimche, Patrice N, Domkam Irenee, Greenwood, Brian, Anthony Ajua, Geoffrey Targett, Brian Greenwood, Targett, Geoffrey, Echouffo-Tcheugui, Justin B, Tawe, Bantar, Ajua Anthony, Ajua, Anthony, Roper Cally, Roper, Cally, Greenwood Brian, Mimche Patrice N, Netongo Palmer M, Akindeh M Nji, Mbacham, Wilfred F, Netongo, Palmer M, Mbacham Wilfred F, Targett Geoffrey, Nji, Akindeh M, Irenee Domkam, Echouffo-Tcheugui Justin B, Marie-Solange B Evehe, Hallett Rachel   +41 more
core   +3 more sources

Cost effectiveness of seasonal intermittent preventive treatment using amodiaquine & artesunate or sulphadoxine-pyrimethamine in Ghanaian children. [PDF]

, 2010
BACKGROUND: Intermittent preventive treatment for malaria in children (IPTc) involves the administration of a full course of an anti-malarial treatment to children under 5 years old at specified time points regardless of whether or not they are known to ...
Kweku Margaret, Daniel Chandramohan, Greenwood Brian, Margaret Kweku, Rosa Legood, Conteh Lesong, Chandramohan, Daniel, Patouillard Edith, Patouillard, Edith, Legood, Rosa, Legood Rosa, Lesong Conteh, Edith Patouillard, Greenwood, Brian, Brian Greenwood, Conteh, Lesong, Kweku, Margaret, Chandramohan Daniel   +17 more
core   +1 more source

Frequency of Pfcrt T76 and Pfdhfr Asn-108 Drug Resistance Mutations in falciparum Malaria in Southeastern Malaria Endemic Area of Iran [PDF]

Iranian Journal of Public Health, 2008
Background: Point mutations in the genes, Pfcrt and Pfdhfr, have been identified elsewhere as strongly associated with re­sistance to chloroquine (CQ) and pyrimethamine, respectively.
MR Razavi, SR Naddaf, JLe Bras, A Raesi, AR Esmaeili, M Assmar   +5 more
doaj   +1 more source

The use of long acting sulfonamides, alone or with pyrimethamine, in malaria (with special reference to sulformetoxine)

Revista da Sociedade Brasileira de Medicina Tropical, 1967
Review of the early literature as well as more recent results show that sulfonamides possess a distinct antimalarial activity. However, when give alone, their action is less marked and slower than that of the antimalarials commonly used in the treatment ...
J. Herrero
doaj   +1 more source

Efficacy of sulphadoxine-pyrimethamine alone or combined with amodiaquine or chloroquine for the treatment of uncomplicated falciparum malaria in Ugandan children.

, 2004
The rapid development of falciparum resistance to sulphadoxine-pyrimethamine (SP) in East and Central Africa has raised concerns as to the efficacy of combining it with another drug.
Langi, P., Egwang, T.G., Thomas G. Egwang, Nalunkuma-Kazibwe, A., Mutabingwa, T.K., Umberto D'Alessandro, Eric Van Marck, Talisuna, Ambrose O, William W. Watkins, Mutabingwa, Theonest K, Watkins, William W, Van Marck, E., Egwang, Thomas G, d' Alessandro, U., Bakyaita, Nathan, D'Alessandro, U., Egwang, T., Mutabingwa, T. K., Watkins, W.W., Langi, Peter, Ambrose O. Talisuna, Nathan Bakyaita, Nalunkuma-Kazibwe, Anne, Bakyaita, N., Watkins, W. W., D'Alessandro, Umberto, Theonest K. Mutabingwa, Peter Langi, Talisuna, A. O., Anne Nalunkuma‐Kazibwe, Van Marck, Eric, Talisuna, A.O.   +31 more
core   +1 more source

Genome comparison of progressively drug resistant Plasmodium falciparum lines derived from drug sensitive clone

Memorias do Instituto Oswaldo Cruz, 2001
Chloroquine has been the mainstay of malaria chemotherapy for the past five decades, but resistance is now widespread. Pyrimethamine or proguanil form an important component of some alternate drug combinations being used for treatment of uncomplicated ...
Ravi Toteja, Lathika Nair, VK Bhasin
doaj   +1 more source

Identification of Prognostic Genes Relevant With the Nuclear Factors of Activated T Cells Based on Transcriptomics in Oral Squamous Cell Carcinoma

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Background It has previously been demonstrated that the nuclear factor of activated T cells (NFAT) is crucial for the development of tumors. Given OSCC's drug resistance and poor outcomes, identifying NFAT‐associated prognostic genes is urgent for better treatment.
Julaiti Tuerxun, Ailimaierdan Ainiwaer, Tairan Ding   +2 more
wiley   +1 more source