Results 51 to 60 of about 22,882 (212)

Gametocytaemia in senegalese children with uncomplicated Falciparum malaria treated with chloroquine, amodiaquine or sulfadoxine + pyrimethamine

Parasite, 2001
Plasmodium falciparum gametocytaemia was studied in 266 Senegalese children (median 4 years, range 0.5-16) with uncomplicated malaria treated with chloroquine (CQ), amodiaquine (AQ) or sulfadoxine+pyrimethamine (SP).
Sokhina C.S, Trape J.-F, Robert V.
doaj   +1 more source

Gametocitemia en malaria por Plasmodium falciparum tratada con amodiaquina o artesunato

Biomédica: revista del Instituto Nacional de Salud, 2008
Introducción. Las relaciones de la gametocitemia de Plasmodium falciparum con el tratamiento antipalúdico han sido poco estudiadas en América. Objetivo.
Jaime Carmona-Fonseca, Eliana Arango, Silvia Blair   +2 more
doaj   +1 more source

Safety of Prenatal Anti‐Infective Use and Offspring Outcomes: A Panoramic Assessment by Indication, Drug Class, and Exposure Characteristics

iMetaMed, EarlyView.
Based on the comprehensive, panoramic assessment of the safety of prenatal anti‐infective use across indications, drug classes, and exposure characteristics, potential safety signals associated with prenatal exposure to several widely used anti‐infective drug classes were identified, including macrolides, metronidazole, tetracyclines, sulfonamides ...
Wenling Wang, Yuezhen Li, Chunrong Liu, Chen Chen, Meng Chen, Lehana Thabane, Xin Sun, Jing Tan   +7 more
wiley   +1 more source

Intensity of transmission and spread of gene mutations linked to chloroquine and sulphadoxine-pyrimethamine resistance in falciparum malaria.

, 2003
The number of malaria parasite clones per infection-multiplicity of parasite clones-is affected by the transmission intensity, multiplicity increases with increasing transmission.
Hastings, Ian M, Langi, P., Talisuna, Ambrose O., Egwang, T.G., Mutabingwa, Theonest K., Speybroeck, Niko, Langi, P, Mutabingwa, T.K., Hastings, Ian, Talisuna, Ambrose O, Mutabingwa, Theonest K, Watkins, William W, Van Marck, E., Egwang, Thomas G, d' Alessandro, U., Egwang, TG, D'Alessandro, U., Egwang, T., Mutabingwa, T. K., Watkins, W.W., Langi, Peter, Mutabingwa, TK, Watkins, W. W., D'Alessandro, Umberto, Hastings, I. M., Hastings, IM, Speybroeck, N., Watkins, William W., Talisuna, A. O., Watkins, WW, Egwang, Thomas G., Van Marck, Eric, Talisuna, A.O., Van Marck, E, Talisuna, AO, Hastings, I.M.   +35 more
core   +1 more source

Perspective for the reproduction of antimalarial drugs in Brazil

Memorias do Instituto Oswaldo Cruz, 1992
The appears to be no chemical manufacture of antimalarial drugs is Brazil. Technology at laboratory process level has been developed for chloroquine, mefloquine, pyrimethamine and cycloquanil, but not perfected nor scaled-up, largely for economic reasons
Benjamin Gilbert
doaj   +1 more source

Anti‐Erythrocyte Antibody Formation in Individuals With and Without Known Sensitisation Pathways Reflecting Indications for Extended Immunohaematology Screening

Journal of Clinical Laboratory Analysis, EarlyView.
– The yearly incidence of anti‐red blood cell antibodies stratified by participant groups and temporal evolution. – Overall significance p = 3.756 × 10−29. ABSTRACT Background Blood transfusion therapies are of vital importance for many patient groups.
Milanka Milosavić, Marko Lilić, Gordana Guzijan, Dušan Vučetić   +3 more
wiley   +1 more source

Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola.

, 2009
OBJECTIVES: To assess the extent of drug resistance in Uige through molecular genetic analysis and to test whether the dhfr triple mutant alleles present in Angola are of southeast Asian origin.
Inojosa WO, Roper C, Bisoffi, Zeno, Bisoffi Z, Ord, Rosalynn, Roper, Cally, Abel PM, Severini C, Pisani, Vincenzo, Matondo A, Warhurst DC, Pisani V, Pearce RJ, Matondo, Alexandre, Warhurst, David C, Severini, Carlo, Menegon M, Menegon, Michela, Inojosa, Walter O, Abel, Paulo M, Majori, Giancarlo, Majori G, Ord R, Pearce, Richard J   +23 more
core   +1 more source

Options for clinical trials of pre and post-natal treatments for congenital toxoplasmosis

Memorias do Instituto Oswaldo Cruz, 2009
Clinical trials comparing different drug regimens and strategies for the treatment of congenital toxoplasmosis and its clinical manifestations in the liveborn child in different clinical settings should aim at formally evaluating the net benefit of ...
Geneviève Chêne, Rodolphe Thiébaut
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial.

, 2005
BACKGROUND: Many countries in Africa are considering a change to combination treatment for falciparum malaria because of the increase in drug resistance. However, there are few effectiveness data for these combinations.
Greenwood, Brian M, Hallett, Rachel, Mutabingwa, Theonest K, Drakeley, Chris, Whitty, Christopher JM, Anthony, Devota, Ahmed, Jalal, Heller, Archie   +7 more
core   +1 more source