Results 41 to 50 of about 22,882 (212)

High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581. [PDF]

, 2009
BACKGROUND: Sulphadoxine-pyrimethamine (SP) a widely used treatment for uncomplicated malaria and recommended for intermittent preventive treatment of malaria in pregnancy, is being investigated for intermittent preventive treatment of malaria in infants
Gesase Samwel, Daniel Chandramohan, Mosha Jacklin F., Mandia, Victor, Joho, Angel, Victor Mandia, Martha Lemnge, Greenwood, Brian, Samwel Gesase, Gesase, Samwel, Chandramohan Daniel, Mosha Frank W., Savael, Zacharia, Ord, Rosalynn, Roper, Cally, Angel Joho, Madebe, Rashid, Greenwood Brian, Hashim Ramadhan, Frank W. Mosha, Mrema Hedwiga, Inbarani Naidoo, Chandramohan, Daniel, Zacharia Savael, Mapunda Ephraim, Mosha, Frank W, Lemnge Martha, Madebe Rashid, Rosalynn Ord, Mapunda, Ephraim, Ephraim Mapunda, Roly D Gosling, Naidoo Inbarani, Frank W Mosha, Hashim, Ramadhan, Cally Roper, Mandia Victor, Gosling, Roly D, Victor M, Jacklin F. Mosha, Gosling Roly D., Lemnge, Martha, Ord Rosalynn, Hedwiga Mrema, Brian Greenwood, Mrema, Hedwiga, Roly D. Gosling, Roper Cally, Jacklin F Mosha, Ramadhan Hashim, Rashid Madebe, Mosha, Jacklin F, Naidoo, Inbarani, Savael Zacharia, Joho Angel   +54 more
core   +2 more sources

Risk of Congenital Toxoplasmosis in Newborns from Mothers with Documented Infection: Experience from Two Referral Centres

Pathogens
During pregnancy, primary Toxoplasma gondii infection can cause congenital toxoplasmosis (CT). We described the newborns’ outcomes from a multicentre cohort of mothers with seroconversion (SC) at different gestational ages.
Alice Bonetti, Agnese Comelli, Annacarla Chiesa, Vania Spinoni, Ambra Vola, Federico Prefumo, Adriana Valcamonico, Carlo Bonfanti, Silvio Caligaris, Lina Rachele Tomasoni, Fausto Baldanti, Valeria Meroni   +11 more
doaj   +1 more source

Pyrimethamine-sensitivity in the presence of BbACc3.

, 2019
Sensitivity profiles are shown for B. bovis CE11, and CE11 transformed with BbACc3 or pBbrad51wt_comp. The presence of either the artificial chromosome, BbACc3, or the integrated construct, pBbrad51wt_comp, results in significant resistance to ...
David R. Allred (7140074), Erin A. Mack (7140068), Yu-Ping Xiao (7140071)   +2 more
core   +1 more source

Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. [PDF]

, 2009
BACKGROUND: Malaria in pregnancy is serious, and drug resistance in Africa is spreading. Drugs have greater risks in pregnancy and determining the safety and efficacy of drugs in pregnancy is therefore a priority.
Greenwood, Brian M, Kandi Muze, Briceño, Marnie, Briceño Marnie, Christopher J. M. Whitty, Whitty Christopher J. M., Mutabingwa, Theonest K, I Muze, Drakeley, Chris, Ord Rosalynn, Chris Drakeley, Whitty, Christopher JM, Theonest K Mutabingwa, Ord, Rosalynn, Mutabingwa Theonest K., Drakeley Chris, Christopher J M Whitty, Theonest K. Mutabingwa, Greenwood Brian M., Brian M Greenwood, Rosalynn Ord, Brian M. Greenwood, Muze Kandi, Muze, Kandi, Marnie Briceño   +24 more
core   +1 more source

Altered life history strategies protect malaria parasites against drugs

Evolutionary Applications, 2018
Drug resistance has been reported against all antimalarial drugs, and while parasites can evolve classical resistance mechanisms (e.g., efflux pumps), it is also possible that changes in life history traits could help parasites evade the effects of ...
Philip L. G. Birget, Megan A. Greischar, Sarah E. Reece, Nicole Mideo   +3 more
doaj   +1 more source

Decreasing burden of malaria in pregnancy in Malawian women and its relationship to use of intermittent preventive therapy or bed nets. [PDF]

PLoS ONE, 2010
The World Health Organization recommends insecticidal bednets and intermittent preventive treatment to reduce malaria in pregnancy. Longitudinal data of malaria prevalence and pregnancy outcomes are valuable in gauging the impact of these antimalarial ...
Gaoqian Feng, Julie A Simpson, Ebbie Chaluluka, Malcolm E Molyneux, Stephen J Rogerson   +4 more
doaj   +1 more source

Origin and dissemination across the Colombian Andes mountain range of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum.

, 2010
The therapeutic efficacy of sulfadoxine-pyrimethamine (SP) in treating uncomplicated Plasmodium falciparum malaria is unevenly distributed in Colombia. The Andes mountain range separates regions in the west where malaria is endemic from those in the east
Osorio, Lyda, GUERRA, ANGELA, Echeverry, Diego F, Roper, Cally, Guerra, Angela P, ECHEVERRY, DIEGO, PEARCE, RICHARD, Corredor, Vladimir, CORREDOR ESPINEL, VLADIMIR, Murillo, Claribel, Benavides, Julie, Pearce, Richard J, Benavides Melo, Julie, Fernández-Cruz K.A., Poblano A., Castro-López C., Marin Agudelo, Hernan Andres, Jiménez-Correa U.   +17 more
core   +1 more source

Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate. [PDF]

, 2007
BACKGROUND: P. falciparum gametocytes may persist after treatment with sulphadoxine-pyrimethamine (SP) plus artesunate (AS) and contribute considerably to malaria transmission.
Alifrangis, M., Mosha, F., Anders Enevold, Bousema, Teun, Arnold Ndaro, Shekalaghe Seif, Shekalaghe, Seif, van Meegeren Monique, Sauerwein Robert, Sauerwein, R.W., Seif Shekalaghe, Gosling Roly, Shekalaghe, S., Ndaro, A., Frank Mosha, Enevold Anders, Drakeley, Chris, Gosling, R., Chris Drakeley, Monique van Meegeren, Teun Bousema, Meegeren, M. van, Robert Sauerwein, van Meegeren, Monique, Enevold, A., Bousema, T., Sauerwein, R., Mosha, Frank, Alifrangis Michael, Drakeley Chris, Bousema Teun, Ndaro Arnold, Gosling, Roly, Drakeley, C., Enevold, Anders, Michael Alifrangis, Alifrangis, Michael, Sauerwein, Robert, Mosha Frank, Meegeren, M.E.R. van, Roly Gosling, Ndaro, Arnold   +41 more
core   +2 more sources

In Vitro Inhibitory Activity of Corilagin and Punicalagin Against Toxoplasma gondii and Their Mechanism(s) of Action

Antibiotics
Background/Objectives: Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. The parasite infection in humans continues to rise due to an increasing seroprevalence rate in domestic and wild warm-blooded animals that serve as a major reservoir ...
Nicole T. Green-Ross, Homa Nath Sharma, Audrey Napier, Boakai K. Robertson, Robert L. Green, Daniel A. Abugri   +5 more
doaj   +1 more source

Eficacia de la combinación amodiaquina más sulfadoxinapirimetamina y de la cloroquina para el tratamiento del paludismo en Córdoba, Colombia, 2006

Biomédica: revista del Instituto Nacional de Salud, 2008
Introducción. La disminución de la eficacia de los medicamentos antipalúdicos en el mundo y en Colombia, dificulta el control de la enfermedad. Objetivo.
Manuel Alberto Pérez, Liliana Jazmín Cortés, Ángela Patricia Guerra, Angélica Knudson, Carlos Usta, Rubén Santiago Nicholls   +5 more
doaj   +1 more source