Results 41 to 50 of about 16,294 (175)

Frequency of Pfcrt T76 and Pfdhfr Asn-108 Drug Resistance Mutations in falciparum Malaria in Southeastern Malaria Endemic Area of Iran [PDF]

Iranian Journal of Public Health, 2008
Background: Point mutations in the genes, Pfcrt and Pfdhfr, have been identified elsewhere as strongly associated with re­sistance to chloroquine (CQ) and pyrimethamine, respectively.
MR Razavi, SR Naddaf, JLe Bras, A Raesi, AR Esmaeili, M Assmar   +5 more
doaj   +1 more source

The use of long acting sulfonamides, alone or with pyrimethamine, in malaria (with special reference to sulformetoxine)

Revista da Sociedade Brasileira de Medicina Tropical, 1967
Review of the early literature as well as more recent results show that sulfonamides possess a distinct antimalarial activity. However, when give alone, their action is less marked and slower than that of the antimalarials commonly used in the treatment ...
J. Herrero
doaj   +1 more source

Understanding Opportunity Costs of Women Participating in Maternal and Child Nutrition Interventions in Southern Angola: Evidence From the MuCCUA Trial

Maternal &Child Nutrition, Volume 22, Issue 3, July 2026.
Economic evaluations of multisectoral nutrition interventions often overlook participants' costs. Using MuCCUA trial data, we estimated women's opportunity costs of three maternal and child nutrition interventions in Angola. Remote participants faced burdens equivalent to 1–1.5 workdays monthly.
Rocio Martin‐Cañavate, Antonio Pujol‐de Castro, Chloe Puett, Elena Trigo, Maria de Lourdes Faria, Ana Silva Gerardo, Antonio Vargas, Israel Molina, Estefania Custodio   +8 more
wiley   +1 more source

Genome comparison of progressively drug resistant Plasmodium falciparum lines derived from drug sensitive clone

Memorias do Instituto Oswaldo Cruz, 2001
Chloroquine has been the mainstay of malaria chemotherapy for the past five decades, but resistance is now widespread. Pyrimethamine or proguanil form an important component of some alternate drug combinations being used for treatment of uncomplicated ...
Ravi Toteja, Lathika Nair, VK Bhasin
doaj   +1 more source

Determinants of Low Birth Weight in Ghana: Analysis of the 2022 Demographic and Health Survey

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Low birth weight (LBW) remains a significant public health challenge in developing countries, contributing substantially to infant mortality and morbidity. Objective To examine sociodemographic, maternal health, and healthcare utilization factors associated with low birth weight in Ghana.
Michael Arthur Ofori, David Kwamena Mensah, Theophilus Asamoah, Michael Fosu Ofori   +3 more
wiley   +1 more source

Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso

Malaria Journal, 2004
The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported.
Traore Corneille, Müller Olaf, Kouyate Bocar   +2 more
doaj   +1 more source

Declining trend of Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant alleles after the withdrawal of Sulfadoxine-Pyrimethamine in North Western Ethiopia. [PDF]

PLoS ONE, 2015
Antimalarial drug resistance is one of the major challenges in global efforts of malaria control and elimination. In 1998, chloroquine was abandoned and replaced with sulfadoxine/pyrimethamine, which in turn was replaced with artemether/lumefantrine for ...
Sofonias K Tessema, Moges Kassa, Amha Kebede, Hussein Mohammed, Gemechu Tadesse Leta, Adugna Woyessa, Geremew Tasew Guma, Beyene Petros   +7 more
doaj   +1 more source

Diagnosis and treatment of endoparasites in pet rabbits

In Practice, Volume 48, Issue 5, Page 258-265, June 2026.
Background: Rabbits are popular pets and members of the veterinary team play a critical role both as providers of species‐specific medical care and a source of informed advice regarding husbandry and preventive medicine. Rabbits can potentially be infected with a somewhat bewildering array of endoparasites, but pathogenicity and significance of ...
Kate Hughes, Richard Saunders
wiley   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Investigate Piperaquine Exposure in Pregnant Women Using an Individualized Profile Approach

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Malaria in pregnancy poses significant risks to the mother, fetus, and neonate, necessitating effective treatment and prevention strategies. This study explored the application of an individualized (‘virtual twin’) physiologically‐based pharmacokinetic (PBPK) modeling approach to the antimalarial drug piperaquine in pregnant women.
Sonia Khier, Myriam El Gaaloul, Joel Tarning, Nada Abla   +3 more
wiley   +1 more source

Anti-inflammatory and Anti-oxidative Effects of Some Medicinal Herbs on Chronic Murine Toxoplasmosis: A Histopathological and Immunohistochemical Study [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases
Background and study aim: Toxoplasma gondii is a globally distributed parasite that causes oxidative stress as a part of the mechanism of neuropathology. The currently available treatments for toxoplasmosis are of limited efficacy because of its distinct
Eman Abd El Rahman, Soad Nada, Nagwa Ibrahim, Rasha Attia, Shereen Ibrahim, Marwa Salama   +5 more
doaj   +1 more source