Results 41 to 50 of about 16,277 (176)
Frequency of Pfcrt T76 and Pfdhfr Asn-108 Drug Resistance Mutations in falciparum Malaria in Southeastern Malaria Endemic Area of Iran [PDF]
Iranian Journal of Public Health, 2008 Background: Point mutations in the genes, Pfcrt and Pfdhfr, have been identified elsewhere as strongly associated with resistance to chloroquine (CQ) and pyrimethamine, respectively.
MR Razavi +5 more
doaj +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 1967 Review of the early literature as well as more recent results show that sulfonamides possess a distinct antimalarial activity. However, when give alone, their action is less marked and slower than that of the antimalarials commonly used in the treatment ...
J. Herrero
doaj +1 more source
Declining trend of Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant alleles after the withdrawal of Sulfadoxine-Pyrimethamine in North Western Ethiopia. [PDF]
PLoS ONE, 2015 Antimalarial drug resistance is one of the major challenges in global efforts of malaria control and elimination. In 1998, chloroquine was abandoned and replaced with sulfadoxine/pyrimethamine, which in turn was replaced with artemether/lumefantrine for ...
Sofonias K Tessema +7 more
doaj +1 more source
Health Science Reports, Volume 9, Issue 4, April 2026.ABSTRACT Background and Aim Malaria poses a major threat to pregnant women in Ghana, especially among marginalized nomadic Fulani communities. This study examined factors influencing insecticide‐treated net (ITN) ownership and use among Fulani pregnant women in northern Ghana. Methods A cross‐sectional survey was carried out between April and June 2022
Yula Salifu +5 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2001 Chloroquine has been the mainstay of malaria chemotherapy for the past five decades, but resistance is now widespread. Pyrimethamine or proguanil form an important component of some alternate drug combinations being used for treatment of uncomplicated ...
Ravi Toteja, Lathika Nair, VK Bhasin
doaj +1 more source
Amitriptyline Induced Life‐Threatening Steven–Johnson Syndrome: Case Report
Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT Stevens–Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine, and carbamazepine are commonly implicated.
Wondwosen Mengist Dereje +3 more
wiley +1 more source
Pharmacoepidemiology and Drug Safety, Volume 35, Issue 3, March 2026.ABSTRACT Purpose Adverse drug reactions (ADRs) present significant obstacles for healthcare systems, impacting both patient safety and the effectiveness of treatments. Despite this, there is a scarcity of research on ADR reports in Sierra Leone, especially over long periods.
Isatu Jalloh +4 more
wiley +1 more source
Malaria Journal, 2004 The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported.
Traore Corneille +2 more
doaj +1 more source
Assessment of the Teratogenic Effect of Sulfadoxine-Pyrimethamine on the Chicken Embryo
Journal of Toxicology, 2022 Background. The sulfadoxine-pyrimethamine combination is a product used in the intermittent preventive treatment (IPT) of malaria in pregnant women in our country. To date, there is very little data on the teratogenic effect of this product.
Rachida Moussa Tari +8 more
doaj +1 more source
Acta Paediatrica, Volume 115, Issue 3, Page 634-642, March 2026.ABSTRACT Aim Growth faltering and loss of development potential are common in low‐ and middle‐income countries. We aimed to study whether linear growth before and after 2 years, height‐for‐age Z‐score (HAZ) from 1 month until 13 years and morbidity during the first 3 years predict adolescent cognitive ability.
Karoliina Videman +6 more
wiley +1 more source