Results 101 to 110 of about 42,597 (297)

Atomic‐Level Engineering of Synthetic Receptors for Enhanced Virus Detection and Removal

Advanced Healthcare Materials, Volume 14, Issue 25, September 26, 2025.
Advanced computational techniques are employed to design and optimize computationally designed imprinted receptors (CIRs) for virus detection and removal. CIR‐conjugated piezoelectric sensor achieves highly sensitive virus detection in water and human serum. CIR‐integrated membranes remove 100% of pathogenic viruses from contaminated water.
Eda Akin, Ekin Sehit, Nastasia Sanda Moldovean‐Cioroianu, Sahana Tavaragondi, Sophia Slenczka, Roderich Süssmuth, Friedrich Jurk, Manuel van Gemmeren, Zeynep Altintas   +8 more
wiley   +1 more source

Examining catastrophic costs and benefit incidence of subsidized antiretroviral treatment (ART) programme in south-east Nigeria.

, 2008
OBJECTIVES: To examine the extent to which costs of subsidized antiretrovirals treatment (ART) programmes are catastrophic and the benefit incidence that accrues to different population groups.
Chukwuka, Chinwe, Dike, Nkem, Ichoku, Hyacinth, Onoka, Chima, Onwujekwe, Obinna, Onyedum, Cajetan, Uzochukwu, Benjamin   +6 more
core   +1 more source

Factors Associated with Severe Disease from Malaria, Pneumonia and Diarrhea among Children in Rural Tanzania - a Hospital-Based Cross-Sectional Study. [PDF]

, 2012
Mild cases of malaria, pneumonia and diarrhea are readily treatable with complete recovery and with inexpensive and widely available first-line drugs. However, treatment is complicated and expensive, and mortality is higher when children present to the ...
Hinderaker, Sven Gudmund, Kahabuka, Catherine, Kvåle, Gunnar   +2 more
core   +2 more sources

Serious Adverse Drug Reactions to Pyrimethamine-Sulphadoxine, Pyrimethamine-Dapsone and to Amodiaquine in Britain [PDF]

Journal of the Royal Society of Medicine, 1990
All reports of adverse reactions with pyrimethamine-sulphadoxine (Fansidar), pyrimethamine-dapsone (Maloprim), and amodiaquine spontaneously reported through the UK national post-marketing system were reviewed. Retrospective reporting rates of serious reactions associated with these drugs were analysed using prescription data from the Department of ...
L J West, P A Phillips-Howard
openaire   +3 more sources

Comprehensive Characterization of the Immune Microenvironment Based on Nested Resampling Machine Learning Framework Identifies TRAF3 Interacting Protein 3 as a Promising Regulator to Improve the Resistance to Immunotherapy in Glioma

Advanced Science, Volume 12, Issue 35, September 18, 2025.
This study develops a nested resampling machine learning framework to establish the Immune Glioma Survival Signature (IGLoS), which stratifies glioma patients and predicts immunotherapy resistance. Multi‐omics analyses reveal TRAF3IP3 as a pivotal regulator of PD‐L1 expression and T‐cell exhaustion via ERK‐NFATC2 signaling.
Yanbo Yang, Fei Wang, Yulian Zhang, Run Huang, Chuanpeng Zhang, Lu Zhao, Hanhan Dang, Xinyu Tao, Yue Lu, Dengfeng Lu, Yunsheng Zhang, Kun He, Jiancong Weng, Zhouqing Chen, Zhong Wang, Yanbing Yu   +15 more
wiley   +1 more source

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. [PDF]

, 2014
Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P.
Adam, Ishag, Ademowo, George, Arze, Cesar, Asaq Molecular Marker Study Group, Baliraine, Frederick N, Berens-Riha, Nicole, Björkman, Anders, Borrmann, Steffen, Checchi, Francesco, Dahal, Prabin, Davis, Timothy ME, Desai, Meghna, Dhorda, Mehul, Djimdé, Abdoulaye A, Dorsey, Grant, El-Sayed, Badria B, Eshetu, Teferi, Eyase, Frederick, Falade, Catherine, Faucher, Jean-François, Fröberg, Gabrielle, Gadalla, Nahla B, Grivoyannis, Anastasia, Guérin, Philippe, Hamour, Sally, Houzé, Sandrine, Johnson, Jacob, Kamugisha, Erasmus, Kariuki, Simon, Kiechel, Jean-René, Kironde, Fred, Kofoed, Poul-Erik, LeBras, Jacques, Malmberg, Maja, Moriera, Clarissa, Mwai, Leah, Mårtensson, Andreas, Ménard, Didier, Ngasala, Billy, Nosten, Francois, Nsanzabana, Christian, Nsobya, Samuel L, Nzila, Alexis, Oguike, Mary, Ogutu, Bernhards, Otienoburu, Sabina Dahlström, Ouédraogo, Jean-Bosco, Piola, Patrice, Plowe, Christopher V, Price, Ric N, Rombo, Lars, Rosenthal, Philip J, Schramm, Birgit, Sibley, Carol Hopkins, Somé, A Fabrice, Stepniewska, Kasia, Sutherland, Colin J, Thwing, Julie, Ursing, Johan, Venkatesan, Meera, Wong, Rina PM, Zeynudin, Ahmed, Zongo, Issaka   +62 more
core   +3 more sources

Identification of Fis1 Interactors in Toxoplasma gondii Reveals a Novel Protein Required for Peripheral Distribution of the Mitochondrion [PDF]

, 2020
Toxoplasma gondii’s single mitochondrion is very dynamic and undergoes morphological changes throughout the parasite’s life cycle. During parasite division, the mitochondrion elongates, enters the daughter cells just prior to cytokinesis, and undergoes ...
Arrizabalaga, Gustavo, Charvat, Robert, Jacobs, Kylie   +2 more
core   +1 more source

Neem (Azadirachta indica): A Miracle Herb; Panacea for All Ailments

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
This comprehensive review highlights the diverse phytochemicals derived from neem leaves, extraction techniques, and their medicinal value in the treatment of multiple medical conditions. This miraculous plant has significant potential for enhanced effectiveness.
Tabussam Tufail, Huma Bader Ul Ain, Aiman Ijaz, Muhammad Adnan Nasir, Ali Ikram, Sana Noreen, Muhammad Tayyab Arshad, Muhammed Adem Abdullahi   +7 more
wiley   +1 more source

New derivatives of the antimalarial drug Pyrimethamine in the control of melanoma tumor growth: an in vitro and in vivo study

Journal of experimental & clinical cancer research : CR, 2016
BackgroundThe antimalarial drug Pyrimethamine has been suggested to exert an antitumor activity by inducing apoptotic cell death in cancer cells, including metastatic melanoma cells.
Chiara Tommasino, L. Gambardella, Maria Buoncervello, R. Griffin, B. Golding, Manuela Alberton, D. Macchia, M. Spada, B. Cerbelli, G. d’Amati, W. Malorni, L. Gabriele, A. M. Giammarioli   +12 more
semanticscholar   +1 more source

The Efficacy of Zinc Supplementation Alone or in Combination for Improving Pregnancy and Infant Outcomes: A Systematic Review and Meta‐Analysis

Journal of Evidence-Based Medicine, Volume 18, Issue 3, September 2025.
ABSTRACT Objective To evaluate zinc supplementation's efficacy in pregnancy, addressing gaps in previous reviews regarding high‐risk subgroups and combination therapies. Methods Systematic review of six databases through March 27, 2025 for randomized controlled trials (RCTs) on prenatal zinc supplementation. Risk of bias was assessed using the Cochrane
Sha Diao, Yuan Feng, Xue Peng, Dan Liu, Liang Huang, Linan Zeng, Lingli Zhang   +6 more
wiley   +1 more source