Results 101 to 110 of about 34,811 (248)

Efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria: revisiting molecular markers in an area of emerging AQ and SP resistance in Mali

Malaria Journal, 2009
Background To update the National Malaria Control Programme of Mali on the efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria.
Wele Mamadou, Dembele Demba, Kone Aminatou, Dama Souleymane, Ouologuem Dinkorma, Fofana Bakary, Sagara Issaka, Maiga Hamma, Beavogui Abdoul H, Djimde Abdoulaye A, Tekete Mamadou, Dicko Alassane, Doumbo Ogobara K   +12 more
doaj   +1 more source

Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.

, 2001
Combination therapy that includes artemisinin derivatives cures most falciparum malaria infections. Lowering transmission by reducing gametocyte infectivity would be an additional benefit.
Targett, G, Drakeley, C, Jawara, M, von Seidlein, L, Coleman, R, Deen, J, Pinder, M, Doherty, T, Sutherland, C, Walraven, G, Milligan, P   +10 more
core   +1 more source

Transgenic pyrimethamine resistant Plasmodium berghei as a model for in vivo anti-DHFR drug testing [PDF]

, 2020
Pongpisid Koonyosying, Natapong Jupatanakul, Jarunee Vanichtanankul, Thanaya Saeyang, Chatpong Pethrak, Jutharat Pengon, Wachiraporn Tipsuwan, Yongyuth Yuthavong, Sumalee Kamchonwongpaisan, Chairat Uthaipibull   +9 more
openalex   +1 more source

The characteristic structural and functional dynamics of P. falciparum DHFR binding with pyrimidine chemotypes implicate malaria therapy design

Chemical Physics Impact
Dihydrofolate reductase (DHFR) enzyme regulates de-novo folate synthesis in Plasmodium falciparum, hence a critical malaria drug target. Pyrimethamine inhibits DHFR, but resistance and lack of cross-species activity are key challenges.
Wande M. Oluyemi, Goodness Nwokebu, Adeniyi T. Adewumi, Shadrach C. Eze, Chinedu C. Mbachu, Emmanuel C. Ogueli, Ngozi Nwodo, Mahmoud E.S. Soliman, Salerwe Mosebi   +8 more
doaj   +1 more source

Therapeutic efficacy test in malaria falciparum in Antioquia, Colombia

Malaria Journal, 2006
Objective Evaluate the frequency of failure of eight treatments for non-complicated malaria caused by Plasmodium falciparum in patients from Turbo (Urabá region), El Bagre and Zaragoza (Bajo Cauca region), applying the 1998 protocol of the World Health ...
Álvarez Tania, Ríos Alexandra, Piñeros Juan G, Carmona-Fonseca Jaime, Blair Silvia, Álvarez Gonzalo, Tobón Alberto   +6 more
doaj   +1 more source

Presumptive Treatment with Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prophylaxis in Children Attending the Sickle Cell Clinic, Mulago Hospital, Uganda: A Randomized Controlled Trial [PDF]

, 2008
Victoria Nakibuuka
openalex   +1 more source

Low-grade sulfadoxine–pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola [PDF]

, 2016
Elsa P. S. Kaingona-Daniel, Larissa Rodrigues Gomes, Bianca Ervatti Gama, Natália Ketrin Almeida-de-Oliveira, Filomeno Fortes, Didier Ménard, Cláudio Tadeu Daniel‐Ribeiro, Maria de Fátima Ferreira‐da‐Cruz   +7 more
openalex   +1 more source

Effects of Drug Policy Changes on Evolution of Molecular Markers of Plasmodium falciparum Resistance to Chloroquine, Amodiaquine, and Sulphadoxine-Pyrimethamine in the South West Region of Cameroon [PDF]

, 2018
Marcel N. Moyeh, Dieudonné Lemuh Njimoh, M.S. Evehe, Innocent Mbulli Ali, Akindeh M. Nji, Dominique N. Nkafu, Palmer Masumbe, Barbara Atogho‐Tiedeu, Valentine Ndikum, Wilfred Fon Mbacham   +9 more
openalex   +1 more source

The impact of maternal antenatal treatment with two doses of azithromycin and monthly sulphadoxine-pyrimethamine on child weight, mid-upper arm circumference and head circumference: A randomized controlled trial.

PLoS ONE, 2019
AimIntermittent preventive treatment in pregnancy (IPTp) with azithromycin and monthly sulfadoxine-pyrimethamine increased the mean child weight, mid-upper arm and head circumference at four weeks of age in a rural low-income setting.
Lotta Hallamaa, Yin Bun Cheung, Mari Luntamo, Ulla Ashorn, Teija Kulmala, Charles Mangani, Per Ashorn   +6 more
doaj   +1 more source

Mutations Associated with Sulfadoxine-Pyrimethamine and Chlorproguanil Resistance in Plasmodium falciparum Isolates from Blantyre, Malawi

, 2020
A. P. Alker, V. Mwapasa, A. Purfield, S. J. Rogerson, M. E. Molyneux, D. D. Kamwendo, E. Tadesse, E. Chaluluka, S. R. Meshnick   +8 more
openalex   +1 more source