Results 81 to 90 of about 34,811 (248)

Examining catastrophic costs and benefit incidence of subsidized antiretroviral treatment (ART) programme in south-east Nigeria.

, 2008
OBJECTIVES: To examine the extent to which costs of subsidized antiretrovirals treatment (ART) programmes are catastrophic and the benefit incidence that accrues to different population groups.
Chukwuka, Chinwe, Dike, Nkem, Ichoku, Hyacinth, Onoka, Chima, Onwujekwe, Obinna, Onyedum, Cajetan, Uzochukwu, Benjamin   +6 more
core   +1 more source

Prevalence and Risk Factors of Iron Deficiency Anemia in Pregnancy in Ghana

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
Key findings: The study investigated the prevalence and risk factors of iron deficiency anemia (IDA) in pregnancy. A prevalence of 81.0% was reported, based on full blood count or hemoglobin levels, indicating a high burden of IDA in the study setting. Identified risk factors included unemployment, age, diet and malaria prophylaxis.
Betty Osei‐Ntiamoah, Yvonne Nartey, Kwadwo Ameyaw Korsah   +2 more
wiley   +1 more source

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine. [PDF]

, 2014
Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P.
Adam, Ishag, Ademowo, George, Arze, Cesar, Asaq Molecular Marker Study Group, Baliraine, Frederick N, Berens-Riha, Nicole, Björkman, Anders, Borrmann, Steffen, Checchi, Francesco, Dahal, Prabin, Davis, Timothy ME, Desai, Meghna, Dhorda, Mehul, Djimdé, Abdoulaye A, Dorsey, Grant, El-Sayed, Badria B, Eshetu, Teferi, Eyase, Frederick, Falade, Catherine, Faucher, Jean-François, Fröberg, Gabrielle, Gadalla, Nahla B, Grivoyannis, Anastasia, Guérin, Philippe, Hamour, Sally, Houzé, Sandrine, Johnson, Jacob, Kamugisha, Erasmus, Kariuki, Simon, Kiechel, Jean-René, Kironde, Fred, Kofoed, Poul-Erik, LeBras, Jacques, Malmberg, Maja, Moriera, Clarissa, Mwai, Leah, Mårtensson, Andreas, Ménard, Didier, Ngasala, Billy, Nosten, Francois, Nsanzabana, Christian, Nsobya, Samuel L, Nzila, Alexis, Oguike, Mary, Ogutu, Bernhards, Otienoburu, Sabina Dahlström, Ouédraogo, Jean-Bosco, Piola, Patrice, Plowe, Christopher V, Price, Ric N, Rombo, Lars, Rosenthal, Philip J, Schramm, Birgit, Sibley, Carol Hopkins, Somé, A Fabrice, Stepniewska, Kasia, Sutherland, Colin J, Thwing, Julie, Ursing, Johan, Venkatesan, Meera, Wong, Rina PM, Zeynudin, Ahmed, Zongo, Issaka   +62 more
core   +4 more sources

FIGO good practice recommendations on anemia in pregnancy, to reduce the incidence and impact of postpartum hemorrhage (PPH)

International Journal of Gynecology &Obstetrics, Volume 171, Issue 3, Page 993-1007, December 2025.
Abstract Anemia affects 32 million pregnant women globally, contributing annually to more than 115 000 maternal deaths and 591 000 perinatal deaths worldwide. Low‐ and middle‐income countries (LMICs) bear the highest burden of anemia in pregnancy, with nearly 50% of affected pregnant women. It is now 2025, which is WHO's target year for a 50% reduction
Akaninyene E. Ubom, Ferdousi Begum, Diana Ramasauskaite, Albaro J. Nieto‐Calvache, Monica Oguttu, Inês Nunes, Zechariah J. Malel, Jolly Beyeza‐Kashesya, Alison Wright, on behalf of the FIGO Committee on Childbirth and Postpartum Hemorrhage   +9 more
wiley   +1 more source

Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of parasitaemic children in Uganda. [PDF]

, 2017
BackgroundPlasmodium falciparum genetic polymorphisms that mediate altered drug sensitivity may impact upon virulence. In a cross-sectional study, Ugandan children with infections mutant at pfcrt K76T, pfmdr1 N86Y, or pfmdr1 D1246Y had about one-fourth ...
Arinaitwe, Emmanuel, Conrad, Melissa, Dorsey, Grant, Greenhouse, Bryan, Kamya, Moses R, Nsobya, Samuel L, Rosenthal, Philip J, Tukwasibwe, Stephen, Tumwebaze, Patrick   +8 more
core   +1 more source

Pregnancy Intentions and Maternal Health Behaviours: Observational Study in 18 African Countries

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 13, Page 2246-2255, December 2025.
ABSTRACT Objective This study explores the relationship between pregnancy intentions and maternal health behaviours. Design and Setting Secondary data analysis of recent (2018–2023), cross‐sectional demographic and health surveys from 18 sub‐Saharan African countries.
Bolanle Olapeju, Anna Maria van Eijk, Michael Bride, Anna Passaniti, Saade Ahmed Abdallah, Gabrielle C. Hunter, Safia Mohammed, Leila Kaze, Judith Nalukwago, Zoé Mistrale Hendrickson   +9 more
wiley   +1 more source

BONCAT-iTRAQ Labelling Reveals Molecular Markers of Adaptive Responses in Toxoplasma gondii to Pyrimethamine Treatment

Pathogens
We employed a BONCAT-iTRAQ labelling approach to investigate newly synthesised proteins (NSPs) in Toxoplasma gondii subjected to varying concentrations of the antifolate drug pyrimethamine.
John G. Mina, Anutthaman Parthasarathy, Exequiel O. Porta, Paul W. Denny, Karunakaran Kalesh   +4 more
doaj   +1 more source

In silico comparative genomics analysis of Plasmodium falciparum for the identification of putative essential genes and therapeutic candidates.

, 2014
A sequence of computational methods was used for predicting novel drug targets against drug resistant malaria parasite Plasmodium falciparum. Comparative genomics, orthologous protein analysis among same and other malaria parasites and protein-protein ...
Altschul, Andrews, Anishetty, Arama, Berman, Bernstein, Bhasin, Boeckmann, Chang, Chawley, Chen, Colovos, Corpet, David Charles Warhurst, Eisenberg, Finn, Franceschini, Ghosh, Irwin, Irwin, Kanehisa, Konc, Krogh, Kushwaha, Larsen, Laskowski, Ludin, Miller, Morris, Mrutyunjay Suar, Mulder, Pieper, Pierleoni, Pontius, Rajani Kanta Mahapatra, Sali, Subhashree Rout, Sun, Tam, von Mering, Wallner, Wiederstein, World Health Organization, Yang, Yeh, Zhexin   +45 more
core   +1 more source

Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space? [PDF]

, 2006
The organization and mining of malaria genomic and post-genomic data is highly motivated by the necessity to predict and characterize new biological targets and new drugs. Biological targets are sought in a biological space designed from the genomic data
Bastien, Olivier, Birkholtz, Lyn-Marie, Breton, Vincent, Grando, Delphine, Hofmann-Apitius, Martin, Jacq, Nicolas, Joubert, Fourie, Kasam, Vinod, Louw, Abraham I, Maréchal, Eric, Ortet, Philippe, Roy, Sylvaine, Saïdani, Nadia, Wells, Gordon, Zimmermann, Marc   +14 more
core   +4 more sources

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source