Results 331 to 340 of about 290,598 (376)
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Pyrimidines. XIII. Novel pyrimidine to pyrimidine transformation reactions
Journal of Heterocyclic Chemistry, 1977AbstractNovel pyrimidine to pyrimidine transformation reactions are described. 1,3‐Dimethyl‐(or diethyl)‐uracil(1) are converted into isocytosine, 2‐thiouracil or uracil derivatives by treatment with guanidine, thiourea or urea, respectively. The latter two cases require base catalysis. The effects of some substituents at C‐5 and C‐6 of 1,3‐dialkylated
Kyoichi A. Watanabe +2 more
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Pyridine and Pyrimidine Derivatives as Privileged Scaffolds in Biologically Active Agents.
Current Medicinal Chemistry, 2020Pyridine and pyrimidine derivatives have received great interest in recent pharmacological research, being effective in the treatment of various malignancies, such as myeloid leukemia, breast cancer and idiopathic pulmonary fibrosis.
M. Chiacchio +4 more
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Recent Development of Pyrimidine‐Containing Antimicrobial Agents
ChemMedChem, 2020Multidrug‐resistant bacterial infections have become an important cause of clinical death in the twenty‐first century. Much effort has been made to overcome this challenge.
Jianxing Zhuang, Shutao Ma
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The Auger spectroscopy of pyrimidine and halogen-substituted pyrimidines
The Journal of Chemical Physics, 2008The C 1s and N 1s Auger spectra of pyrimidine, 2-chloropyrimidine, and 5-bromopyrimidine have been measured in an electron impact experiment at 1000 eV. In the case of the halogen-substituted pyrimidines, also the Cl 2p and Br 3d Auger spectra have been recorded.
Storchi L +5 more
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Synthetic chemistry of pyrimidines and fused pyrimidines: A review [PDF]
Synthetic Communications, 2016 AbstractReview: 100 refs.
Selvaraj Mohana Roopan, Rajesh Sompalle
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, 2016
Effects of electron donating (−CH3 and −OH) and electron withdrawing (−NO2) substituents on the corrosion inhibition efficiency of four glucosamine-based, substituted, pyrimidine-fused heterocycles (CARBs) on mild steel corrosion in 1 M HCl have been ...
C. Verma +4 more
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Effects of electron donating (−CH3 and −OH) and electron withdrawing (−NO2) substituents on the corrosion inhibition efficiency of four glucosamine-based, substituted, pyrimidine-fused heterocycles (CARBs) on mild steel corrosion in 1 M HCl have been ...
C. Verma +4 more
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ChemInform, 1999
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Susana Fernández +3 more
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Susana Fernández +3 more
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A Review on Synthesis, Anticancer and Antiviral Potentials of Pyrimidine Derivatives
Current Bioactive Compounds, 2019Pyrimidine is the six membered heterocyclic aromatic compound similar to benzene and pyridine containing two nitrogen atoms at 1st and 3rd positions.
Sanjiv Kumar, A. Deep, B. Narasimhan
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Anticancer pyrimidines, pyrimidine nucleosides and prodrugs
1990Of the plethora of pyrimidines, pyrimidine nucleosides, analogues and prodrug derivatives that have been synthesised and evaluated as anticancer agents, only two are in general clinical use. The long-studied 5-fluorouracil (5-FUra (1), see Scheme 9.1), and some nucleoside and prodrug derivatives, are used regularly for the treatment of breast cancer ...
M. J. Robins, M. MacCoss
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Roles of Pyridine and Pyrimidine Derivatives as Privileged Scaffolds in Anticancer Agents.
Mini-Reviews in Medical Chemistry, 2017BACKGROUND Cancer has been considered to be a global health concern due to the impact of disease on the quality of life. The continual increase of cancer cases as well as the resistance of cancer cells to the existing drugs have driven the search for ...
Supaluk Prachayasittikul +6 more
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