Results 341 to 350 of about 290,598 (376)
New Pyrimidine Pathway involved in the Biosynthesis of the Pyrimidine of Thiamine [PDF]
Nature, 1967 OUR, studies with mutants of Salmonella typhimurium LT2 have revealed that the pyrimidine moiety of thiamine is synthesized by a new biosynthetic route using intermediates from the purine biosynthetic pathway. Radioactive labelling has indicated that the conventional nucleic acid pyrimidine biosynthetic pathway is not used for biosynthesis of the ...
Peter C. Newell, R. G. Tucker
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Journal of the Iranian Chemical Society, 2019
Compound 1 condensed with benzaldehyde to produce styryl pyrimidine 2. Pyridopyrimidines 5, 8 and 10 resulted from [4 + 2] cycloaddition (condensation) of 1 with malononitrile, ethyl cyanoacetate and/or ethyl acetoacetate. Compound 1 was also concerted to pyridopyrimidine 14 through multistep reaction (hydrolysis, chlorination, isothiocyanate formation
Hamed Y. Moustafa +4 more
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Compound 1 condensed with benzaldehyde to produce styryl pyrimidine 2. Pyridopyrimidines 5, 8 and 10 resulted from [4 + 2] cycloaddition (condensation) of 1 with malononitrile, ethyl cyanoacetate and/or ethyl acetoacetate. Compound 1 was also concerted to pyridopyrimidine 14 through multistep reaction (hydrolysis, chlorination, isothiocyanate formation
Hamed Y. Moustafa +4 more
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The problem with pyrimidines [PDF]
Nature Structural & Molecular Biology, 1996 The chemical properties of cytosine present cells with a serious informational ‘disease’, necessitating enzymes with exquisite specificity for deoxyuridine for its prevention and cure.
Laurence H. Pearl, Renos Savva
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Receptors for Purines and Pyrimidines
Pharmacological Reviews, 1998### A. Overview Extracellular purines (adenosine, ADP, and ATP) and pyrimidines (UDP and UTP) are important signaling molecules that mediate diverse biological effects via cell-surface receptors termed purine receptors.
Vera Ralevic, Geoffrey Burnstock
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De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence
Nature Cell Biology, 2023Chuanzhen Yang +11 more
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1987
Nucleic acids are comprised of nitrogenous bases (purines and pyrimidines), pentose sugars (ribose and deoxyribose) and phosphate groups. Specific sequences of purines and pyrimidines encode the genetic information of cells and organisms.
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Nucleic acids are comprised of nitrogenous bases (purines and pyrimidines), pentose sugars (ribose and deoxyribose) and phosphate groups. Specific sequences of purines and pyrimidines encode the genetic information of cells and organisms.
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Remote meta-C-H Cyanation of Arenes Enabled by a Pyrimidine-Based Auxiliary.
Angewandte Chemie, 2017An easily removable pyrimidine-based auxiliary has been employed for the remote meta-C-H cyanation of arenes. The scope of this Pd-catalyzed cyanation reaction using copper(I) cyanide as the cyanating agent was demonstrated with benzylsilanes ...
Sukdev Bag +5 more
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Pest Management Science, 2017
BACKGROUND Aedes aegypti is a major mosquito vector for the transmission of serious diseases, especially dengue and yellow fever. More than 1 billion people in developing countries are at risk.
Xinghai Liu +7 more
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BACKGROUND Aedes aegypti is a major mosquito vector for the transmission of serious diseases, especially dengue and yellow fever. More than 1 billion people in developing countries are at risk.
Xinghai Liu +7 more
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Chemistry, 2016
A series of green butterfly-shaped thermally activated delayed fluorescence (TADF) emitters, namely PXZPM, PXZMePM, and PXZPhPM, are developed by integrating an electron-donor (D) phenoxazine unit and electron-acceptor (A) 2-substituted pyrimidine moiety
Kailong Wu +7 more
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A series of green butterfly-shaped thermally activated delayed fluorescence (TADF) emitters, namely PXZPM, PXZMePM, and PXZPhPM, are developed by integrating an electron-donor (D) phenoxazine unit and electron-acceptor (A) 2-substituted pyrimidine moiety
Kailong Wu +7 more
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The Effect of Different Purines and Pyrimidines on Human Pyrimidine Biosynthesis
1977Hereditary orotaciduria is caused by the patient’s inability to convert orotic acid to uridine monophosphate, due to an absence of the activity of orotidine phosphate decarboxylase in all cases and orotate phosphoribosyl-transferase in all cases but one. All or nearly all of the orotic acid formed by biosynthesis must be excreted or degraded. Therefore,
A. Rauch-Janssen +2 more
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