Results 111 to 120 of about 11,360 (191)

Reversible Assembly and Disassembly of σ‐Aromatic B3 Rings

Chemistry – A European Journal, EarlyView.
B3 rings are the smallest σ‐aromatic boron compounds. Here, we show for the first time that cationic diboranes with an electron‐precise (2c,2e) bond can be reversibly converted to σ‐aromatic B3 rings with electron‐deficient (3c,2e) bonding. Base‐induced disassembly of the B3 ring leads back to cationic diboranes and monoborane adducts.
Julian Krauß, Frederick Koch, Niels Karsten Paul Hecht, Elisabeth Kaifer, Hans‐Jörg Himmel   +4 more
wiley   +1 more source

Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction

Molecules
The relevance of the asymmetric Biginelli reaction (ABR) has been increased in this century, due to the pharmacological application of its products. This review focuses predominantly on articles published in the period from 2015 to 2024 on asymmetric ...
Marcos Díaz-Fernández, Manuel Algarra, Saturnino Calvo-Losada, José-Joaquín Quirante, Francisco Sarabia, María-Soledad Pino-González   +5 more
doaj   +1 more source

Regioisomerism Rewires Optical and Ion Recognition Properties in Azulenylsumanenes—Curved Non‐Alternant π‐Systems

Chemistry – A European Journal, EarlyView.
Regioisomerism rewires orbital topology and electronic polarity in curved non‐alternant π‐systems, switching both optical response and alkali metal ion recognition from Na+ to Rb+ selectivity. ABSTRACT Herein, we explore the fundamental concept of combining the molecular curvature of a molecular fragment of buckminsterfullerene with the pronounced ...
Jakub Cyniak, Anna Mazur, Bartłomiej Pigulski, Hidehiro Sakurai, Artur Kasprzak   +4 more
wiley   +1 more source

Uncatalyzed Guanosine Phosphorylation under Potentially Prebiotic Conditions

Chemistry – A European Journal, EarlyView.
Pyrophosphate acts as phosphorylating agent of guanosine under simple wet‐dry cycles without condensing agent and inorganic catalysts to afford cyclic guanosine monophosphate derivatives useful for oligomerization in prebiotic processes. ABSTRACT The phosphorylation of nucleosides and their subsequent polymerization are key issues in the study of the ...
Martina Proietti, Bruno Mattia Bizzarri, Elisa De Marchi, Alessandra Giorgi, Raffaele Saladino, Giovanna Costanzo   +5 more
wiley   +1 more source

Classical and Nonclassical Antifolates: Synthesis of Furo-[2,3-d] Pyrimidines Pyrrolo[2,3-d]Pyrimidines and Pyrimido-[4, 5-b]-Indoles [PDF]

, 2010
The dissertation will give an introduction, background and our research progress in the areas of antifolates. The design and synthesis of both classical and nonclassical bicyclic furo[2,3-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and tricyclic pyrimido[4 ...
Wang, Lei
core  

DNA Nanotechnology Meets Peptide and Protein Self‐Assembly

Chemistry – A European Journal, EarlyView.
Combining DNA nanotechnology with peptide and protein assembly provides complementary platforms for the rational engineering of functional biomaterials. This Perspective discusses the emerging field of self‐assembling DNA‐peptide and DNA‐protein hybrid systems that combine the structural precision and programmability of DNA nanotechnology with the ...
Marcel Hanke, Nanjundan Raghul, Adrian Keller, Veikko Linko, Verónica I. Dodero   +4 more
wiley   +1 more source

Site‐Specific Enzymatic Syntheses of DNA Bearing Several Modifications From RNA or DNA Templates

Chemistry – A European Journal, EarlyView.
A single‐tube protocol for enzymatic synthesis of DNA containing 1–3 site‐specific nucleobase modifications was developed based on repeated single nucleotide extension, primer extension, and exchange of template. ABSTRACT Two approaches for the enzymatic synthesis of DNA oligonucleotides (ONs) bearing multiple site‐specific modifications were explored.
Lukáš Kaiser, Veronika Raindlová, Michal Hocek   +2 more
wiley   +1 more source

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

Clinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung, Nicholas Ieronimakis, Bothaina Mousa, Emily D. Sheikh, Sarah E. Ligon, Joshua W. Monson, Jennifer R. Damicis, Hillary J. Kinsman, Lydia E. Bettridge, Samuel L.M. Arnold, Edward J. Kelly, Jashvant D. Unadkat, Joanne Wang   +12 more
wiley   +1 more source

Dihydropyrimidine Dehydrogenase Genotype–Phenotype Correlations in Plasma and Peripheral Blood Mononuclear Cells

Clinical Pharmacology &Therapeutics, EarlyView.
The chemotherapeutic 5‐fluorouracil (5‐FU) is commonly used to treat solid tumors, especially colorectal cancer. Deleterious variants in DPYD, which encodes dihydropyrimidine dehydrogenase (DPD), are strongly associated with severe and potentially lethal 5‐FU toxicity.
Brianna M. Bembenek, Seid Hamzic, Kelly J. Bouchonville, Carlo R. Largiadèr, Steven M. Offer   +4 more
wiley   +1 more source

Sustainable Hydrogen Production by Glycerol and Monosaccharides Catalytic Acceptorless Dehydrogenation (AD) in Homogeneous Phase

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Sustainable hydrogen production can be obtained from hydogen‐rich biomass‐derived organic molecules through Acceptorless Dehydrogenation (AD) reactions. Glycerol and sugars are available in large quantities from industry and can be successfully used as substrates in AD protocols, in the presence of tailored, selective, easily tunable and thermally ...
Sylwia Kostera, Luca Gonsalvi
wiley   +1 more source