Results 101 to 110 of about 11,360 (191)
Pyrrolo[2,3-d]pyrimidines : design, synthesis, functionalisation
Les pyrrolo[2,3-d]pyrimidines, également connues sous le nom de 7-déazapurines, sont une classe importante d’hétérocycliques aromatiques, de par leurs potentiels biologiques (antitumoral, antiinflammatoire, antibactérien, etc.).
Prieur, Vanessa
core
Optimized MS/MS settings of pyrimidines and related metabolites.
Optimized MS/MS settings of pyrimidines and related metabolites.
Sven F. Garbade (3700849) +9 more
core +1 more source
Accelerating green heterocyclic synthesis: Convergence of AI, automation, and sustainable chemistry
Green heterocyclic synthesis and data‐driven tools such as AI, high‐throughput experimentation, continuous flow, and self‐driving laboratories have developed largely in parallel. This review connects them and asks how green metrics such as E‐factor and PMI might serve as explicit optimization targets rather than post‐hoc measures, toward sustainable ...
Noor Aisyah Ahmad Shah +8 more
wiley +1 more source
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon +3 more
wiley +1 more source
In this study, structurally functionalized 1,2,4-triazolo[4,3-a]pyrimidines and pyrido[2,3-d]pyrimidines were synthesized by two non-metal DABCO-based ionic liquids which were compared in catalytic activity in both reactions.
M. Irankhah-Khanghah +4 more
core +1 more source
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
Synthesis of some 2,4-diamino-pyrrolo-pyrimidines
Some new 2, 4-diamino-pyrrolo-pyrimidines have been synthesized.
Merchant, J. R. +3 more
core +1 more source
Chalcogen‐based compounds are explored as versatile tools to enhance the stability and performance of halide perovskites. Their roles in defect passivation, ion migration suppression, and interface engineering are analyzed, along with impacts on device efficiency.
Atanu Jana +4 more
wiley +1 more source
Synthesis of novel thiazolo[5,4-d]pyrimidines
1229-1234 2-Methylsulphanyl-5-aminothiazole-4-carboxamide 1 has been used as a convenient precursor for the synthesis of new thiazolo[4,5-e][1,2,4-triazolo][4,3-c]pyrimidines 5 and the corresponding tetrazolo analogue 7.
Chattopadhyay, Gautam +4 more
core

