Results 101 to 110 of about 73,935 (281)
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu +4 more
wiley +1 more source
From quantum groups to genetic mutations
In the framework of the crystal basis model of the genetic code, where each codon is assigned to an irreducible representation of $U_{q \to 0}(sl(2) \oplus sl(2))$, single base mutation matrices are introduced.
Sciarrino, Antonino
core
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley +1 more source
Ultraviolet selection pressure on the earliest organisms [PDF]
Effects of UV selection pressure on evolutionary development patterns of early ...
Sagan, C.
core +1 more source
Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives
Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome +6 more
wiley +1 more source
Absorption of pyrimidines, purines, and nucleosides by Co, Ni, Cu and Fe /III-montmorillonite /clay-organic studies XIII/ [PDF]
Absorption of pyrimidines, purines, and nucleosides by copper, nickel, cobalt, and iron ...
Brindley, G. W. +2 more
core +1 more source
From monoclonal antibody to gene for a neuron-specific glycoprotein in Drosophila [PDF]
A monoclonal antibody (MAb24B10), derived from mice immunized with Drosophila retina, exclusively stains photoreceptor cells in the retina and their axonal projections to the optic ganglia. The antigen (Ag24B10) is a 160-kDa glycoprotein comprising about
Benzer, Seymour +2 more
core
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran +4 more
wiley +1 more source
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source

