Results 91 to 100 of about 48,430 (295)
Pyrrolo[2,3-d]pyrimidines : conception, synthèse, fonctionnalisation
, 2015 The pyrrolo [2,3-d]pyrimidines, also known as 7-deazapurines, are an important class of aromatic heterocycles by their biological potencial (antitumor, anti-inflammatory, antibacterial, etc.).
Prieur, Vanessa
core +1 more source
Pyrimidine Acyclo-C-Nucleosides by Ring Transformations of 2-Formyl-L-arabinal
Molecules, 2005 The protected 2-formyl-L-arabinal 2 reacted with thiourea and cyanamide in the presence of sodium hydride to afford via ring transformations the 5-[1R,2S-1,2- bis(benzyloxy)-3-hydroxypropyl]-1,2-dihydropyrimidines 3 and 4, respectively.
Klaus Peseke +3 more
doaj +1 more source
Synthesis of pyrido[1,2-[alpha symbol] ]pyrimidine scaffolds and their DNA-binding studies
, 2014 Access to thesis permanently restricted to Ball State community only.Access to abstract permanently restricted to Ball State community only.Thesis (M.S.)Department of ChemistryIntroduction to pyrido[1,2- [alpha symbol] ]pyrimidines and their synthesis ...
Habarakada Liyanage, Thakshila Udayakanthi Liyanage
core
Late‐Stage Functionalization of Peptides on the Solid Phase
Angewandte Chemie International Edition, EarlyView.Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
Diverse Methods with Stereoselective Induction in the Asymmetric Biginelli Reaction
MoleculesThe relevance of the asymmetric Biginelli reaction (ABR) has been increased in this century, due to the pharmacological application of its products. This review focuses predominantly on articles published in the period from 2015 to 2024 on asymmetric ...
Marcos Díaz-Fernández +5 more
doaj +1 more source
Cine and direct aminations of 5- and 6-halogenopyrimidines : a mechanistic study
, 1978 This thesis describes investigations into the mechanistic aspects of the cine amination of 4-substituted 5-halogenopyrimidines and the direct amination of 4-substituted 6-halogenopyrimidines by potassium amide in liquid ammonia.PMR spectra of some 4-R-5 ...
Rasmussen, C.A.H.
core
, 2010 Pyrrolo[2,3-d]pyrimidines and pyrazino[2,3-d]pyrimidines were synthesised to investigate their biological activities to eventually produce potential new antifolates.
Lee, Jeong-Hwan
core +1 more source
A Universal Nucleoside‐to‐Nucleoside‐5′‐Triphosphate Enzyme Cascade Driven by Polyphosphate
Angewandte Chemie International Edition, EarlyView.Nucleoside‐5′‐triphosphates (NTPs) are essential components for the generation of nucleic acids, yet their chemical synthesis is hindered by the low yield of nucleoside phosphorylation. Here, we present a universal, two‐enzyme nucleoside‐to‐NTP cascade that is driven by polyphosphate.
Jonathan P. Suess +1 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2014 An extension of the substrate scope of the Flögel-three-component reaction of lithiated alkoxyallenes, nitriles and carboxylic acids is presented. The use of dicarboxylic acids allowed the preparation of symmetrical bis(β-ketoenamides) from simple ...
Mrinal K. Bera +3 more
doaj +1 more source
SYNTHESIS OF 5-SUBSTITUTED PYRIMIDINES.
, 1963 SYNTHESIS OF 5-SUBSTITUTED ...
TARAKAD VENKATESWAR. RAJKUMAR (7989017)
core