Results 21 to 30 of about 73,935 (281)

Triethylamine-Promoted Oxidative Cyclodimerization of 2H-Azirine-2-carboxylates to Pyrimidine-4,6-dicarboxylates: Experimental and DFT Study

Molecules, 2023
An unprecedented oxidative cyclodimerization reaction of 2H-azirine-2-carboxylates to pyrimidine-4,6-dicarboxylates under heating with triethylamine in air is described. In this reaction, one azirine molecule undergoes formal cleavage across the C-C bond
Timofei N. Zakharov, Pavel A. Sakharov, Mikhail S. Novikov, Alexander F. Khlebnikov, Nikolai V. Rostovskii   +4 more
doaj   +1 more source

C–C (alkynylation) vs C–O (ether) bond formation under Pd/C–Cu catalysis: synthesis and pharmacological evaluation of 4-alkynylthieno[2,3-d]pyrimidines

Beilstein Journal of Organic Chemistry, 2011
The Pd/C–CuI–PPh3 catalytic system facilitated C–C bond formation between 4-chlorothieno[2,3-d]pyrimidines and terminal alkynes in methanol with high selectivity without generating any significant side products arising from C–O bond formation between the
Dhilli Rao Gorja, K. Shiva Kumar, K. Mukkanti, Manojit Pal   +3 more
doaj   +1 more source

Surface-enhanced Raman spectroscopy of DNA bases [PDF]

, 1986
A Raman microprobe has been used to measure the surface-enhanced Raman spectra of adenine, guanine, cytosine and thymine. Comparison of the SERS spectrum with solution spectra shows that some line positions are not influenced by the adsorption process ...
Greve, J., Mul, F.F.M. de, Otto, C., Tweel, T.J.J. van den   +3 more
core   +3 more sources

In Silico Screening of the Library of Pyrimidine Derivatives as Thymidylate Synthase Inhibitors for Anticancer Activity

E-Journal of Chemistry, 2009
We here report the virtual screening of several series of pyrimidine derivatives for in silico Thymidylate Synthase (TS) inhibition to arrive at possible potential inhibitors of TS with acceptable pharmacokinetic or ADME (Absorption, Distribution ...
A. G. Nerkar, S. A. Ghone, A. K. Thaker
doaj   +1 more source

Comparative assessment of stability of fungicides triazolopyrimidine, triazole, pyrimidine and morpholine in the soil and prediction of groundwater pollution with them.

Medičnì Perspektivi, 2016
The purpose of our study was prediction of ground water contamination with fungicides of different chemical classes in soil-climatic conditions of Ukraine and other European countries and hygienic assessment of their harmful effects on human health.
S. V. Bіlous, S. T. Omel'chuk, O. P. Vavrіnevich, A. M. Antonenko   +3 more
doaj   +1 more source

In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus. [PDF]

, 2016
Packaging of the genome into a protein capsid and its subsequent delivery into a host cell are two fundamental processes in the life cycle of a virus. Unlike double-stranded DNA viruses, which pump their genome into a preformed capsid, single-stranded ...
Dai, Xinghong, Du, Yushen, Lai, Mason, Li, Zhihai, Shu, Sara, Sun, Ren, Zhou, Z Hong   +6 more
core   +1 more source

Synthesis, characterisation and biological activities of N-phenyl-ethan-1-one-2,4-dimethyl-1,3-butadiene-1,4-thiazin derivatives

Tikrit Journal of Pure Science, 2023
A facile synthesis of some new 1, 2- thiazine derivatives by the Claisen-Schmidt reaction-induced aldolic condensation of enolizable aromatic ketones with substituted benzaldehydes, and then they were treated with urea and thiourea to obtain the ...
Nabaz Abdulmajeed Mohammad Salih
doaj   +1 more source

Elevated Level of DNA Damage and Impaired Repair of Oxidative DNA Damage in Patients with Recurrent Depressive Disorder [PDF]

, 2015
Background: Depressive disorder (DD), including recurrent DD (rDD), is a severe psychological disease, which affects a large percentage of the world population.
Bielecka-Kowalska, Anna, Czarny, Piotr, Gałecki, Piotr, Kacperska, Dagmara, Kawczyńska, Daria, Kwiatkowski, Dominik, Orzechowska, Agata, Szemraj, Janusz, Talarowska, Monika, Śliwiński, Tomasz   +9 more
core   +1 more source

Parallel Synthesis of 2-Substituted 6-(5-Oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides

Molecules, 2012
A library of 24 6-(5-oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides <strong>10</strong>{<em>1</em>,<em>2</em>; <em>1–12</em>} was prepared by a parallel solution-phase approach.
Branko Stanovnik, Uroš Grošelj, Jurij Svete, Georg Dahmann, Drago Kočar, Jernej Baškovč, Bojana Črček   +6 more
doaj   +1 more source

Influence of 5-hydroxymethyluracil on the dynamics of angiogenic growth factors in the perioperative period of surgical myocardial revascularization: results of a randomized trial

Российский кардиологический журнал, 2023
Aim. To evaluate the effect of 5-hydroxymethyluracil on the dynamics of angiogenic growth factors in the perioperative period of surgical myocardial revascularization.Material and methods.
B. A. Oleynik, V. V. Plechev, V. A. Evdakov, R. I. Izhbuldin, N. Sh. Zagidullin   +4 more
doaj   +1 more source