Results 31 to 40 of about 48,617 (303)

Pyrimidines- and purines-rich sequences of miRNAs. [PDF]

open access: yes, 2016
The table shows the content of the pyrimidines or purines nucleotides according to the sequence of miRNAs. The total contents of purines or pyrimidines of the miRNAs presented in the table is above 90%.
Jan Barciszewski (55070)   +6 more
core   +1 more source

Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2‑a]pyrimidines and Pyrazolo[1,5‑a]pyrimidines [PDF]

open access: yes, 2017
A palladium-catalyzed intramolecular dehydrogenative coupling reaction was developed for the synthesis of fused imidazo­[1,2-a]­pyrimidines and pyrazolo­[1,5-a]­pyrimidines.
Siva K. Reddy Kotla (2032867)   +4 more
core   +3 more sources

Parallel Synthesis of 2-Substituted 6-(5-Oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides

open access: yesMolecules, 2012
A library of 24 6-(5-oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides <strong>10</strong>{<em>1</em>,<em>2</em>; <em>1–12</em>} was prepared by a parallel solution-phase approach.
Branko Stanovnik   +6 more
doaj   +1 more source

Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2‑a]pyrimidines and Pyrazolo[1,5‑a]pyrimidines [PDF]

open access: yes, 2017
A palladium-catalyzed intramolecular dehydrogenative coupling reaction was developed for the synthesis of fused imidazo[1,2-a]pyrimidines and pyrazolo[1,5-a]- pyrimidines.
Wang, Jeh-Jeh   +9 more
core   +2 more sources

Iron-Catalyzed Alkyne-Based Multicomponent Synthesis of Pyrimidines under Air [PDF]

open access: yes, 2021
An iron-catalyzed sustainable, economically affordable, and eco-friendly synthetic protocol for the construction of various trisubstituted pyrimidines is described.
Gargi Chakraborty   +9 more
core   +1 more source

Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease

open access: yesFrontiers in Endocrinology, 2018
The maintenance of a healthy deoxyribonucleotide triphosphate (dNTP) pool is critical for the proper replication and repair of both nuclear and mitochondrial DNA.
Raquel Buj, Katherine M. Aird
doaj   +1 more source

Search for antibacterial activity in a number of new S-derivatives (1,2,4-triazole-3(2H)-yl)methyl)thiopyrimidines

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021
The relevance of the study of 1,2,4-triazole derivatives with pyrimidine fragment is due to the synthesis of potential broad-spectrum antibacterial drugs, low molecular weight inducers of interferon, and antitumor agents, search for molecular descriptors
Yu. V. Karpenko, O. I. Panasenko
doaj   +1 more source

Characterization of Amide Bond Conformers for a Novel Heterocyclic Template of N-acylhydrazone Derivatives

open access: yesMolecules, 2013
Herein we describe NMR experiments and structural modifications of 4-methyl-2-phenylpyrimidine-N-acylhydrazone compounds (aryl-NAH) in order to discover if duplication of some signals in their 1H- and 13C-NMR spectra was related to a mixture of imine ...
Alexandra Basilio Lopes   +5 more
doaj   +1 more source

Synthesis of substituted 8H-benzo[h]pyrano[2,3-f]quinazolin-8-ones via photochemical 6π-electrocyclization of pyrimidines containing an allomaltol fragment

open access: yesBeilstein Journal of Organic Chemistry, 2023
For the first time, we elaborated a method for the synthesis of pyrimidines containing an allomaltol unit. The suggested approach is based on the reaction of 2-(1-(dimethylamino)-3-oxo-3-arylprop-1-en-2-yl)-3-hydroxy-6-methyl-4H-pyran-4-ones with ...
Constantine V. Milyutin   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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