Results 61 to 70 of about 48,617 (303)

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

open access: yesAdvanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena   +3 more
wiley   +1 more source

Pyrimidines. Part X : Synthesis of Some Bis(Aryloxy) Pyrimidines [PDF]

open access: yes, 1976
Department of Applied Chemistry, University Colleges of Science and Technology, Calcutta University. Calcutta-9 Manuscript received 18 November 1975; accepted 3 August 1976 Synthesis of some 2, 4-bis(aryloxy)-6-aminopyrimidine.
P. K. DUTTA, D. SEN
core   +1 more source

Pyrrolo[2,3-d]pyrimidines : conception, synthèse, fonctionnalisation [PDF]

open access: yes, 2015
The pyrrolo [2,3-d]pyrimidines, also known as 7-deazapurines, are an important class of aromatic heterocycles by their biological potencial (antitumor, anti-inflammatory, antibacterial, etc.).
Prieur, Vanessa
core   +3 more sources

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

open access: yesAdvanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan   +6 more
wiley   +1 more source

Synthesis of pyrido[1,2-[alpha symbol] ]pyrimidine scaffolds and their DNA-binding studies [PDF]

open access: yes, 2014
Access to thesis permanently restricted to Ball State community only.Access to abstract permanently restricted to Ball State community only.Thesis (M.S.)Department of ChemistryIntroduction to pyrido[1,2- [alpha symbol] ]pyrimidines and their synthesis ...
Habarakada Liyanage, Thakshila Udayakanthi Liyanage
core  

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

Cine and direct aminations of 5- and 6-halogenopyrimidines : a mechanistic study [PDF]

open access: yes, 1978
This thesis describes investigations into the mechanistic aspects of the cine amination of 4-substituted 5-halogenopyrimidines and the direct amination of 4-substituted 6-halogenopyrimidines by potassium amide in liquid ammonia.PMR spectra of some 4-R-5 ...
Rasmussen, C.A.H.
core  

Synthesis of pyrrolo[2,3-d]pyrimidines and pyrazino[2,3-d]pyrimidines and their biological activities [PDF]

open access: yes, 2010
Pyrrolo[2,3-d]pyrimidines and pyrazino[2,3-d]pyrimidines were synthesised to investigate their biological activities to eventually produce potential new antifolates.
Lee, Jeong-Hwan
core   +2 more sources

Pyrimidine Acyclo-C-Nucleosides by Ring Transformations of 2-Formyl-L-arabinal

open access: yesMolecules, 2005
The protected 2-formyl-L-arabinal 2 reacted with thiourea and cyanamide in the presence of sodium hydride to afford via ring transformations the 5-[1R,2S-1,2- bis(benzyloxy)-3-hydroxypropyl]-1,2-dihydropyrimidines 3 and 4, respectively.
Klaus Peseke   +3 more
doaj   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang   +11 more
wiley   +1 more source

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