Results 151 to 160 of about 3,637 (213)

A plain language summary describing changes in pain associated with uterine fibroids among women receiving relugolix combination therapy. [PDF]

Pain Manag
Stewart EA, Lukes AS, Venturella R, Ferreira JA, Li Y, Hunsche E, Wagman RB, Al-Hendy A.   +7 more
europepmc   +1 more source

Synthesis and structure-activity relationship of liposomal substrates for phospholipase A(2) [PDF]

, 2011
Clausen, Mads Hartvig, Viart, Helene Marie-France   +1 more
core  

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real-world study. [PDF]

Int J Cancer
Tang X, Sun JJ, Wan Z, Jing XY, Guo X, Gao J.   +5 more
europepmc   +1 more source

Conformationally rigid histone deacetylase inhibitors correct DF508-CFTR protein function [PDF]

, 2011
Balch, William E., Ghadiri, M. Reza, Hutt, Darren M., Leman, Luke J., Maryanoff, Bruce E., Montero, Ana, Olsen, Christian Adam, Vickers, Chris J.   +7 more
core  

Nanoparticle-Catalysed Microwave-Driven MCRs for Sustainable Heterocycle Synthesis. [PDF]

Molecules
Kasi V, Jeleń M, Chu XH, Karthikeyan P, Młodawska BM, Tey LH.   +5 more
europepmc   +1 more source

Recent advances in zirconium-based catalysis and its applications in organic synthesis: a review. [PDF]

RSC Adv
Bibi S, Zubair M, Riaz R, Kanwal A, Ali Shah SA.   +4 more
europepmc   +1 more source

A single-center retrospective study of dabrafenib plus trametinib combination therapy in patients with BRAF V600E-positive thyroid cancer. [PDF]

Int J Clin Oncol
Ando T, Oya Y, Tomiie Y, Ogawa K, Kuki T, Tanabe Y, Kato H, Imaizumi K, Hibi Y, Kawada K.   +9 more
europepmc   +1 more source

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Synthesis of fluorinated pyrimidinones

Journal of Fluorine Chemistry, 2013
Abstract A method for the construction of fluorinated pyrimidinones based on the reaction of cyanodifluoromethyl-substituted amines with isocyanates is described. The use of ortho-iodophenylisocyanate in this reaction followed by copper catalyzed intramolecular amination affords fluorinated fused heterocycles – 4-fluoropyrimido[1,6-a]benzimidazol-1 ...
Mikhail D Kosobokov, Marina I Struchkova, Dmitry E Arkhipov   +2 more
exaly   +2 more sources

Pyrimidinones as reversible metaphase arresting agents

European Journal of Medicinal Chemistry, 1993
Abstract 5-Halo- N (1)-substituted 2(1 H )-pyrimidinones have the ability to cause reversible arrest of mitosis during metaphase. Highly active compounds have a heteroatom ( O , S or N ) in the β-position of the N (1)-carbon chain which is further substituted by an aryl group. In vitro data have been provided.
T Benneche, R Oftebro, Kjell Undheim
exaly   +2 more sources

New Pyrimidinone and Fused Pyrimidinone Derivatives as Potential Anticancer Chemotherapeutics

Archiv der Pharmazie, 2012
AbstractA series of novel substituted pyrimidinones and fused pyrimidinones (compounds 3–18) were synthesized starting with oxiranylmethanone 2. The in vitro cytotoxicity against a human breast adenocarcinoma (MCF‐7) cell line was investigated and most of the tested compounds showed potent cytotoxic activity against the MCF‐7 cell line comparable to ...
Aymn E, Rashad, Ahmed H, Shamroukh, Nabil M, Yousif, Mowafia A, Salama, Hatem S, Ali, Mamdouh M, Ali, Abeer E, Mahmoud, Mahmoud, El-Shahat   +7 more
openaire   +2 more sources