Results 171 to 180 of about 3,637 (213)

SNAr Reactions of 2-Methylthio-4-pyrimidinones in Pivalic Acid: Access to Functionalized Pyrimidinones and Pyrimidines

Synthesis, 2012
Pivalic acid is a useful medium to effect the direct SNAr displacement of 2-methylthio-4-pyrimidinones with a variety of anilines. Products are easily isolated in good to excellent yields, and following chlorination, provide an opportunity to rapidly query structure-activity relationships at the 4-position of functionalized pyrimidines.
Matthew Maddess, Rhiannon Carter
openaire   +1 more source

Fluorescent 2‐Pyrimidinone Nucleoside in Parallel‐Stranded DNA

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Kaluzhny, D., Mikhailov, S., Efimtseva, E., Borisova, O., Florentiev, V., Shchyolkina, A., Jovin, T.   +6 more
openaire   +3 more sources

A simple approach for the regioselective synthesis of imidazo[1,2-a]pyrimidiones and pyrimido[1,2-a]pyrimidinones

Tetrahedron, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
David Font, Anthony Linden, Montserrat Heras, Jose M. Villalgordo   +3 more
openaire   +1 more source

Conformation of 1,2,3,4-tetrahydro-2-pyrimidinones

Chemistry of Heterocyclic Compounds, 1981
The conformation of a number of 1,2,3,4-tetrahydro-2-pyrimidinones with various substituents in the ring was established on the basis of the vicinal 3J34 constants found from the 1H NMR spectra of these compounds. It is shown that in solution rapid conformational transformations between the two possible “boat” conformations evidently occur.
�. �. Liepin'sh, E. L. Khanina, G. Ya. Dubur   +2 more
openaire   +1 more source

Regioselectivity in reactions of alkynylmetal complexes with pyrimidinones

Journal of Organometallic Chemistry, 1985
Abstract Regioselectivity is observed in 1 1 -adduct formation between phenylethynyltriisopropoxytitanium and 2(1/ H )-pyrimidinones; the new carbon-carbon bond is formed at C(4). In contrast the 3,4- and 3,6-dihydro products are formed together from the corresponding magnesium and lithium reagents, but from the magnesium compound the major ...
Frode Rise, Kjell Undheim
openaire   +1 more source

An efficient synthesis of thiazolo[3,2-a]pyrimidinones

Tetrahedron Letters, 2010
A series of thiazolo[3,2-a]pyrimidinones was synthesised in a two-step procedure, using Eaton's reagent to effect cyclisation of 2-aminothiazoles. The use of relatively low temperatures, facile product isolation and short reaction times make this cyclisation procedure a particularly attractive option over more conventional methods.
Nadia M. Ahmad, Keith Jones
openaire   +1 more source

Phenylation of pyrimidinones using diphenyliodonium salts

Journal of the Chemical Society, Perkin Transactions 1, 1999
Pyrimidinones 1 have been phenylated under basic conditions using diphenyliodonium salts, and the effect of substituents on the yield and regiochemistry has been studied.
Stig André Jacobsen, Synne Rødbotten, Tore Benneche   +2 more
openaire   +1 more source

Recent Developments in the Synthesis of Bicyclic Condensed Pyrimidinones

Current Organic Chemistry, 2022
Rupesh Kumar, Vipan Kumar, Gaurav Bhargava   +2 more
exaly  

Preparation of 2-pyrimidinone and derivatives

Collection of Czechoslovak Chemical Communications, 1975
V. Uchytilová, A. Holý, D. Cech, J. Gut   +3 more
openaire   +1 more source

Antiviral and other bioactivities of pyrimidinones

Pharmacology & Therapeutics, 1985
openaire   +2 more sources