Results 191 to 200 of about 5,835 (244)

ChemInform Abstract: Photochemistry of 4‐Pyrimidinones. Part 7. Reaction of Dewar 4‐Pyrimidinone with Methylamine.

Chemischer Informationsdienst, 1982
AbstractDie Photolyse der Pyrimidinone (I) in flüssigem Methylamin (II) führt zu den offenkettigen Produkten (III), die bei der Chromatographie an Aluminiumoxid zu den Pyrimidinonen (IV) cyclisieren.
Y. HIRAI, H. KANMEI, T. YAMAZAKI, S. HIROKAMI   +3 more
openaire   +1 more source

Synthesis and biological activities of 2-pyrimidinone nucleosides. 2. 5-Halo-2-pyrimidinone 2'-deoxyribosides

Journal of Medicinal Chemistry, 1985
1-(2-Deoxy-beta-D-ribofuranosyl)-5-bromo-2-pyrimidinone (BrPdR) and 1-(2-deoxy-beta-D-ribofuranosyl)-5-iodo-2-pyrimidinone (IPdR) have been synthesized by condensation of the appropriate silylated bases 2a and 2b, respectively, with 3,5-bis-O-(p-chlorobenzoyl)-2-deoxy-alpha-D-ribofuranosyl chloride (8) in 1,2-dichloroethane, in the presence of SnCl4 ...
S M, Efange, E M, Alessi, H C, Shih, Y C, Cheng, T J, Bardos   +4 more
openaire   +2 more sources

Antineoplastic properties of pyrimidinone interferon inducers

Advances in Enzyme Regulation, 1981
Abstract The interferon inducing, antiviral and antitumor activities of a new series of pyrimidinone compounds are compared and summarized in this report. An interesting split in mechanism of action appeared to exist in these compounds. One group represented by ABPP were very potent interferon inducing agents and the antiviral and antitumor activity ...
openaire   +2 more sources

SNAr Reactions of 2-Methylthio-4-pyrimidinones in Pivalic Acid: Access to Functionalized Pyrimidinones and Pyrimidines

Synthesis, 2012
Pivalic acid is a useful medium to effect the direct SNAr displacement of 2-methylthio-4-pyrimidinones with a variety of anilines. Products are easily isolated in good to excellent yields, and following chlorination, provide an opportunity to rapidly query structure-activity relationships at the 4-position of functionalized pyrimidines.
Matthew Maddess, Rhiannon Carter
openaire   +1 more source

Fluorescent 2‐Pyrimidinone Nucleoside in Parallel‐Stranded DNA

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Kaluzhny, D., Mikhailov, S., Efimtseva, E., Borisova, O., Florentiev, V., Shchyolkina, A., Jovin, T.   +6 more
openaire   +3 more sources

A simple approach for the regioselective synthesis of imidazo[1,2-a]pyrimidiones and pyrimido[1,2-a]pyrimidinones

Tetrahedron, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
David Font, Anthony Linden, Montserrat Heras, Jose M. Villalgordo   +3 more
openaire   +1 more source

Conformation of 1,2,3,4-tetrahydro-2-pyrimidinones

Chemistry of Heterocyclic Compounds, 1981
The conformation of a number of 1,2,3,4-tetrahydro-2-pyrimidinones with various substituents in the ring was established on the basis of the vicinal 3J34 constants found from the 1H NMR spectra of these compounds. It is shown that in solution rapid conformational transformations between the two possible “boat” conformations evidently occur.
�. �. Liepin'sh, E. L. Khanina, G. Ya. Dubur   +2 more
openaire   +1 more source

Regioselectivity in reactions of alkynylmetal complexes with pyrimidinones

Journal of Organometallic Chemistry, 1985
Abstract Regioselectivity is observed in 1 1 -adduct formation between phenylethynyltriisopropoxytitanium and 2(1/ H )-pyrimidinones; the new carbon-carbon bond is formed at C(4). In contrast the 3,4- and 3,6-dihydro products are formed together from the corresponding magnesium and lithium reagents, but from the magnesium compound the major ...
Frode Rise, Kjell Undheim
openaire   +1 more source

Green Synthesis and Urease Inhibitory Activity of Spiro-Pyrimidinethiones/Spiro-Pyrimidinones-Barbituric Acid Derivatives

Iranian journal of pharmaceutical research, 2015
Sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) with pore size 6 nm as an efficient heterogeneous nanoporous solid acid catalyst exhibited good catalytic activity in the Biginelli-like reaction in the synthesis of spiroheterobicyclic rings with good ...
Ghodsi Mohammadi Ziarani, S. Asadi, Sakineh Faramarzi, M. Amanlou   +3 more
semanticscholar   +1 more source

An efficient synthesis of thiazolo[3,2-a]pyrimidinones

Tetrahedron Letters, 2010
A series of thiazolo[3,2-a]pyrimidinones was synthesised in a two-step procedure, using Eaton's reagent to effect cyclisation of 2-aminothiazoles. The use of relatively low temperatures, facile product isolation and short reaction times make this cyclisation procedure a particularly attractive option over more conventional methods.
Nadia M. Ahmad, Keith Jones
openaire   +1 more source