Characterization of Gastrointestinal Absorption of Salmon Milt-Derived Oligodeoxyribonucleic Acids in Mice [PDF]
Journal of Nutrition and MetabolismDietary nucleic acids exert physiological effects beyond serving as substrates for nucleic acid synthesis; however, their exact molecular forms that are absorbed in the small intestine remain unclear.
Fuyu Hayashi +8 more
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Hydrolysis of Oligodeoxyribonucleotides on the Microarray Surface and in Solution by Catalytic Anti-DNA Antibodies in Systemic Lupus Erythematosus [PDF]
Current Issues in Molecular Biology, 2023 Anti-DNA antibodies are known to be classical serological hallmarks of systemic lupus erythematosus (SLE). In addition to high-affinity antibodies, the autoantibody pool also contains natural catalytic anti-DNA antibodies that recognize and hydrolyze DNA.
Tatiana S. Novikova +6 more
doaj +2 more sources
Efficiency of genome editing using modified single-stranded oligodeoxyribonucleotides in human cells [PDF]
Scientific ReportsSingle-stranded oligodeoxyribonucleotide (ssODN) gene editing has emerged as a promising therapeutic strategy. However, further improvements in efficiency are desired for practical application.
Seryoung Kim +3 more
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THE ENZYMATIC CONDENSATION OF OLIGODEOXYRIBONUCLEOTIDES WITH POLYDEOXYRIBONUCLEOTIDES [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1964 exaly +3 more sources
Molecules, 2023 Raman nanoparticle probes are a potent class of optical labels for the interrogation of pathological and physiological processes in cells, bioassays, and tissues.
Monica-Cornelia Sardaru +4 more
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Biomolecules, 2020 Human neutrophils are the first line of defense against bacterial and viral infections. They eliminate pathogens through phagocytosis, which activate the 5-lipoxygenase (5-LOX) pathway resulting in synthesis of leukotrienes.
Ekaterina A. Golenkina +6 more
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Facile enzymatic synthesis of base J-containing oligodeoxyribonucleotides and an analysis of the impact of base J on DNA replication in cells. [PDF]
PLoS ONE, 2014 We reported here the use of T4 bacteriophage β-glucosyltransferase (T4 β-GT) for the facile synthesis of base J-containing oligodeoxyribonucleotides (ODNs). We found that the enzyme could catalyze the glucosylation of 5-hydroxymethyl-2-deoxyuridine (5hmU)
Debin Ji, Yinsheng Wang
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Synthesis and radioiodination of a stannyl oligodeoxyribonucleotide [PDF]
Nucleic Acids Research, 1997 Synthesis and radioiodination of a stannyl oligodeoxyribonucleotide were undertaken to evaluate a gamma ray emitting ODN ligand for thrombus imaging in vivo . Synthesis of the ODN was based on modified automatedbeta-cyanoethyl phosphoramidite chemistry with an organotin nucleoside (dU*) coupled to a thrombin binding aptamer sequence to give d(U ...
H, Dougan +3 more
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Anomalous hairpin formation in an oligodeoxyribonucleotide [PDF]
Nucleic Acids Research, 1985 An accurate method for deriving molar absorptivity-temperature profiles applied to a set of single-stranded oligodeoxyribonucleotides shows that the undecamer CGAGTTTGACGp exists in a hairpin conformation involving Watson-Crick base pairing between the two terminal CG dinucleotides.
J G, Nadeau, P T, Gilham
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A Solution to the Common Problem of the Synthesis and Applications of Hexachlorofluorescein Labeled Oligonucleotides. [PDF]
PLoS ONE, 2016 A common problem of the preparation of hexachlorofluorescein labeled oligonucleotides is the transformation of the fluorophore to an arylacridine derivative under standard ammonolysis conditions. We show here that the arylacridine byproduct with distinct
Andrey N Chuvilin +4 more
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