Results 1 to 10 of about 4,769 (178)

Experimental optimization of probe length to increase the sequence specificity of high-density oligonucleotide microarrays [PDF]

BMC Genomics, 2007
Background High-density oligonucleotide arrays are widely used for analysis of genome-wide expression and genetic variation. Affymetrix GeneChips – common high-density oligonucleotide arrays – contain perfect match (PM) and mismatch (MM) probes generated
Kashiwagi Akiko, Furusawa Chikara, Ono Naoaki, Suzuki Shingo, Yomo Tetsuya   +4 more
doaj   +3 more sources

A new method for sequence analysis of oligodeoxyribonucleotides [PDF]

Nucleic Acids Research, 1985
The structure of an oligodeoxyribonucleotide may be determined by a simple two-dimensional separation on a polyethyleneimine-cellulose thin layer sheet. Chromatography in the first dimension fractionates by chain length a nested set of fragments that are generated by subjecting the oligomer to partial spleen phosphodiesterase degradation and then ...
D M, Black, P T, Gilham
openaire   +4 more sources

Immobilization of oligodeoxyribonucleotides with multiple anchors to microchips [PDF]

Nucleic Acids Research, 2001
Facile modification of oligodeoxyribonucleotides is required for efficient immobilization to a pre-activated glass surface. This report presents an oligodeoxyribonucleotide which contains a hairpin stem-loop structure with multiple phosphorothioate moieties in the loop.
Satyam Nampalli, Xiaodong Zhao
exaly   +3 more sources

Cleavage of oligodeoxyribonucleotides from controlled-pore glass supports and their rapid deprotection by gaseous amines [PDF]

Nucleic Acids Research, 1996
A Wilk, E E Max, Serge L Beaucage
exaly   +2 more sources

The isopropoxyacetic group for convenient base protection during solid-support synthesis of oligodeoxyribonucleotides and their triester analogs

Nucleic Acids Research, 1989
Bogdan Uznanski, Andrzej Grajkowski, A Wilk   +2 more
exaly   +3 more sources

THE ENZYMATIC CONDENSATION OF OLIGODEOXYRIBONUCLEOTIDES WITH POLYDEOXYRIBONUCLEOTIDES [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1964
exaly   +3 more sources

Inhibition of Human Immunodeficiency Virus Type 1-mediated Cytopathic Effects by Poly(L-lysine)-conjugated Synthetic Antisense Oligodeoxyribonucleotides

Journal of General Virology, 1989
Mario Stevenson, Patrick L Iversen
exaly   +3 more sources

Nucleic Acid Probes in Bio-Imaging and Diagnostics: Recent Advances in ODN-Based Fluorescent and Surface-Enhanced Raman Scattering Nanoparticle and Nanostructured Systems

Molecules, 2023
Raman nanoparticle probes are a potent class of optical labels for the interrogation of pathological and physiological processes in cells, bioassays, and tissues.
Monica-Cornelia Sardaru, Narcisa-Laura Marangoci, Rosanna Palumbo, Giovanni N. Roviello, Alexandru Rotaru   +4 more
doaj   +1 more source

The Potential of Telomeric G-Quadruplexes Containing Modified Oligoguanosine Overhangs in Activation of Bacterial Phagocytosis and Leukotriene Synthesis in Human Neutrophils

Biomolecules, 2020
Human neutrophils are the first line of defense against bacterial and viral infections. They eliminate pathogens through phagocytosis, which activate the 5-lipoxygenase (5-LOX) pathway resulting in synthesis of leukotrienes.
Ekaterina A. Golenkina, Galina M. Viryasova, Nina G. Dolinnaya, Valeria A. Bannikova, Tatjana V. Gaponova, Yulia M. Romanova, Galina F. Sud’ina   +6 more
doaj   +1 more source

Facile enzymatic synthesis of base J-containing oligodeoxyribonucleotides and an analysis of the impact of base J on DNA replication in cells. [PDF]

PLoS ONE, 2014
We reported here the use of T4 bacteriophage β-glucosyltransferase (T4 β-GT) for the facile synthesis of base J-containing oligodeoxyribonucleotides (ODNs). We found that the enzyme could catalyze the glucosylation of 5-hydroxymethyl-2-deoxyuridine (5hmU)
Debin Ji, Yinsheng Wang
doaj   +1 more source