Results 41 to 50 of about 12,307 (190)
Advanced Science, Volume 13, Issue 9, 13 February 2026.This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li +22 more
wiley +1 more source
Conjugation of 5′‐Functionalized Oligodeoxyribonucleotides with Properly Functionalized Ligands [PDF]
, 2001 This unit reports the synthesis of oligodeoxyribonucleotides covalently linked via their 5′ termini to various ligands such as intercalating agents, reactive groups, or labels.
Asseline, Ulysse +3 more
core +1 more source
Biological Templates for Gold Nanocluster Assembly: Design and Biomedical Applications
Aggregate, Volume 7, Issue 2, February 2026.The review discusses the fundamental properties of ultrasmall gold nanoclusters and their surface modification strategies for targeted biomedical use. It examines biologically guided assembly processes and their effects on optical behavior, particularly aggregation‐induced emission.
Zeineb Ayed +3 more
wiley +1 more source
Synthesis and Biochemical Evaluation of Phosphonoformate Oligodeoxyribonucleotides
, 2016 Phosphonoformate oligodeoxyribonucleotides were prepared via a solid phase synthesis strategy. The first step in the preparation of appropriate synthons was condensation of bis(N,N-diisopropylamino)phosphine and diphenylmethylsilylethyl chloroformate in ...
Christina M. Yamada (2643211) +2 more
core +1 more source
Human Mutation, Volume 2026, Issue 1, 2026.Germline DDX41 variants are found in up to 4% of patients with acute myeloid leukemia (AML) and myelodysplastic neoplasms (MDSs), with a higher prevalence among males and a late onset. In this study, we analyzed 647 Danish patients with suspected myeloid neoplasms to assess the frequency of germline DDX41 variants and the functional impact of variants ...
Nikolaj Juul Nitschke +16 more
wiley +1 more source
Synthesis and Purification of Oligodeoxyribonucleotides: A Modified Approach
, 1987 A reduction in monomer consumption in the solid phase synthesis of oligodeoxyribonucleotides has been achieved by introducing a repeat coupling approach.
Kadalayil, Latha P. +4 more
core +2 more sources
Cellular Physiology and Biochemistry, 2018 Background/Aims: MicroRNAs play an important role in regulating myocardial infarction (MI)-induced cardiac injury. MicroRNA-124 (miR-124) plays a vital role in regulating cellular proliferation, differentiation and apoptosis.
Fang He +8 more
doaj +1 more source
Analysis of efficiency of purification of HEX-oligonucleotides obtained by modified deblocking
Тонкие химические технологии, 2012 A new way of deblocking of synthetic hexachlorofluorescein-oligodeoxyribonucleotides (HEX-ODN) prevents the modification of the label and the accumulation of difficult to separated by-product.
A. G. Mosina +4 more
doaj
Microwave-assisted rapid deprotection of oligodeoxyribonucleotides [PDF]
Nucleic Acids Research, 1997 A novel method for the deprotection of oligodeoxyribonucleotides under microwave irradiation has been developed. The oligodeoxynucleotides having base labile, phenoxyacetyl (pac), protection for exocyclic amino functions were fully deprotected in 0. 2 M sodium hydroxide (methanol:water : : 1:1, v/v) = A and 1 M sodium hydroxide (methanol:water : : 1:1,
P, Kumar, K C, Gupta
openaire +2 more sources
Юг России: экология, развитиеAim. To investigate the cell entry and antiretroviral properties of modified oligodeoxyribonucleotides targeting highly conserved regions of the HIV‐1 genome: the study was conducted using modified oligonucleotides containing phosphorothioate ...
L. G. Gotfrid +4 more
doaj +1 more source