Results 41 to 50 of about 11,432 (197)
Direct Attachment of Conjugate Groups to the 5′ Terminus of Oligodeoxyribonucleotides [PDF]
, 2000 This unit gives protocols for the attachment of intercalating and photoreactive conjugate groups to oligodeoxyribonucleotides. Protocols are given for acridine‐ and psoralen‐conjugated oligonucleotides, and include attachment of the linker, preparation ...
Asseline, Ulysse +3 more
core +1 more source
Oligodeoxyribonucleotides used in this study.
, 2019 Oligodeoxyribonucleotides used in this study.
Kazuo Yamagata (128504) +6 more
core +1 more source
Microwave-assisted rapid deprotection of oligodeoxyribonucleotides [PDF]
Nucleic Acids Research, 1997 A novel method for the deprotection of oligodeoxyribonucleotides under microwave irradiation has been developed. The oligodeoxynucleotides having base labile, phenoxyacetyl (pac), protection for exocyclic amino functions were fully deprotected in 0. 2 M sodium hydroxide (methanol:water : : 1:1, v/v) = A and 1 M sodium hydroxide (methanol:water : : 1:1,
P, Kumar, K C, Gupta
openaire +2 more sources
Convenient synthesis of arabinonucleoside containing oligodeoxyribonucleotides [PDF]
Nucleic Acids Symposium Series, 2000 C2 substituted arabinofuranosyluracil derivatives were synthesized and its incorporations into DNA were easily carried out by using post-synthetic modification.
H, Ozaki +3 more
openaire +2 more sources
Journal of Lipid Research, 2004 High glucosylceramide synthase (GCS) activity is one factor contributing to multidrug resistance (MDR) in breast cancer. Enforced GCS overexpression has been shown to disrupt ceramide-induced apoptosis and to confer resistance to doxorubicin.
Yong-Yu Liu +6 more
doaj +1 more source
BMC Genomics, 2007 Background High-density oligonucleotide arrays are widely used for analysis of genome-wide expression and genetic variation. Affymetrix GeneChips – common high-density oligonucleotide arrays – contain perfect match (PM) and mismatch (MM) probes generated
Kashiwagi Akiko +4 more
doaj +1 more source
A new method for sequence analysis of oligodeoxyribonucleotides [PDF]
Nucleic Acids Research, 1985 The structure of an oligodeoxyribonucleotide may be determined by a simple two-dimensional separation on a polyethyleneimine-cellulose thin layer sheet. Chromatography in the first dimension fractionates by chain length a nested set of fragments that are generated by subjecting the oligomer to partial spleen phosphodiesterase degradation and then ...
D M, Black, P T, Gilham
openaire +2 more sources
Advanced Functional Materials, Volume 36, Issue 33, 23 April 2026.We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj +21 more
wiley +1 more source
MedComm, Volume 7, Issue 3, March 2026.Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia +4 more
wiley +1 more source