Results 51 to 60 of about 11,432 (197)
Conjugation of 5′‐Functionalized Oligodeoxyribonucleotides with Properly Functionalized Ligands [PDF]
, 2001 This unit reports the synthesis of oligodeoxyribonucleotides covalently linked via their 5′ termini to various ligands such as intercalating agents, reactive groups, or labels.
Asseline, Ulysse +3 more
core +1 more source
Advanced Science, Volume 13, Issue 9, 13 February 2026.This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li +22 more
wiley +1 more source
Biological Templates for Gold Nanocluster Assembly: Design and Biomedical Applications
Aggregate, Volume 7, Issue 2, February 2026.The review discusses the fundamental properties of ultrasmall gold nanoclusters and their surface modification strategies for targeted biomedical use. It examines biologically guided assembly processes and their effects on optical behavior, particularly aggregation‐induced emission.
Zeineb Ayed +3 more
wiley +1 more source
, 2016 A Highly Efficient Synthesis of Oligodeoxyribonucleotides Containing the 2‘-Deoxyribonolactone ...
Eric Defrancq (1557424) +3 more
core +1 more source
Cellular Physiology and Biochemistry, 2018 Background/Aims: MicroRNAs play an important role in regulating myocardial infarction (MI)-induced cardiac injury. MicroRNA-124 (miR-124) plays a vital role in regulating cellular proliferation, differentiation and apoptosis.
Fang He +8 more
doaj +1 more source
Human Mutation, Volume 2026, Issue 1, 2026.Germline DDX41 variants are found in up to 4% of patients with acute myeloid leukemia (AML) and myelodysplastic neoplasms (MDSs), with a higher prevalence among males and a late onset. In this study, we analyzed 647 Danish patients with suspected myeloid neoplasms to assess the frequency of germline DDX41 variants and the functional impact of variants ...
Nikolaj Juul Nitschke +16 more
wiley +1 more source
Synthesis and Biochemical Evaluation of Phosphonoformate Oligodeoxyribonucleotides
, 2016 Phosphonoformate oligodeoxyribonucleotides were prepared via a solid phase synthesis strategy. The first step in the preparation of appropriate synthons was condensation of bis(N,N-diisopropylamino)phosphine and diphenylmethylsilylethyl chloroformate in ...
Christina M. Yamada (2643211) +2 more
core +1 more source
Synthesis of oligodeoxyribonucleotide N3′→P5′ phosphoramidates
Nucleic Acids Research, 1995 An efficient synthesis of the novel nucleic acid analogs oligodeoxyribonucleotide N3'-->P5' phosphoramidates, where the 3'-oxygen is substituted by a 3'-nitrogen, is described. Synthesis of the title compounds was accomplished by the following synthetic steps. First, 5'-O-DMT base-protected-3'-amino-2',3'-dideoxynucleosides were prepared.
J K, Chen +3 more
openaire +3 more sources
Analysis of efficiency of purification of HEX-oligonucleotides obtained by modified deblocking
Тонкие химические технологии, 2012 A new way of deblocking of synthetic hexachlorofluorescein-oligodeoxyribonucleotides (HEX-ODN) prevents the modification of the label and the accumulation of difficult to separated by-product.
A. G. Mosina +4 more
doaj
Improvements in the phosphoramidite procedure for the synthesis of oligodeoxyribonucleotides
Nucleic Acids Research, 1983 The paper describes an improved method for the synthesis of oligodeoxyribonucleotides using phosphoramidite chemistry. Our procedure relies on novel phosphoramidite intermediates, the deoxyribonucleoside-3'-morpholine-methoxyphosphins. These compounds are extremely stable and can be purified readily.
T, Dörper, E L, Winnacker
openaire +3 more sources