Results 201 to 210 of about 5,835 (244)

Pyrimidinones. 1. 2-Amino-5-halo-6-aryl-4(3H)-pyrimidinones. Interferon-inducing antiviral agents

Journal of Medicinal Chemistry, 1985
Interferon induction and antiviral activity was discovered with 2-amino-5-bromo-6-phenyl-4(3H)-pyrimidinone. An analogue study incorporating a series of 2-amino-5-substituted-6-arylpyrimidinones revealed that the most potent interferon inducers were mono- and difluorophenyl analogues.
H I, Skulnick, S D, Weed, E E, Eidson, H E, Renis, W, Wierenga, D A, Stringfellow   +5 more
openaire   +2 more sources

Synthesis and computational studies of novel fused pyrimidinones as a promising scaffold with analgesic, anti-inflammatory and COX inhibitory potential.

European journal of medicinal chemistry, 2021
Mona F. Said, Hanan H. Georgey, Eman R Mohammed   +2 more
semanticscholar   +1 more source

Phenylation of pyrimidinones using diphenyliodonium salts

Journal of the Chemical Society, Perkin Transactions 1, 1999
Pyrimidinones 1 have been phenylated under basic conditions using diphenyliodonium salts, and the effect of substituents on the yield and regiochemistry has been studied.
Stig André Jacobsen, Synne Rødbotten, Tore Benneche   +2 more
openaire   +1 more source

Synthesis of Biologically Active 6-(Tolylhydrazinylidene)Pyrazolo[1,5-a]Pyrimidinones

Chemistry of Heterocyclic Compounds, 2020
Y. Burgart, N. A. Elkina, E. Shchegolkov, O. Krasnykh, V. Maslova, G. Triandafilova, S. Solodnikov, G. Makhaeva, O. Serebryakova, E. Rudakova, V. Saloutin   +10 more
semanticscholar   +1 more source

Pyrimidinones

Reactions Weekly, 2017
openaire   +1 more source

Mesoionic pyrido[1,2-a]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide1.

Bioorganic & Medicinal Chemistry Letters, 2017
Wenming Zhang, C. Holyoke, Thomas F Pahutski, G. Lahm, James D. Barry, Daniel Cordova, R. Leighty, Vineet Singh, Dan Vicent, M. T. Tong, K. A. Hughes, S. Mccann, Yewande T. Henry, Ming-Ben Xu, Twyla A. Briddell   +14 more
semanticscholar   +1 more source

Mesoionic pyrido[1,2-a]pyrimidinones: Discovery of dicloromezotiaz as a lepidoptera insecticide acting on nicotinic acetylcholine receptors1,2.

Bioorganic & Medicinal Chemistry Letters, 2017
Wenming Zhang, C. Holyoke, James D. Barry, Daniel Cordova, R. Leighty, M. T. Tong, K. A. Hughes, G. Lahm, Thomas F Pahutski, Ming-Ben Xu, Twyla A. Briddell, S. Mccann, Yewande T. Henry, Yuzhong Chen   +13 more
semanticscholar   +1 more source

Recent Developments in the Synthesis of Bicyclic Condensed Pyrimidinones

Current Organic Chemistry, 2022
Rupesh Kumar, Vipan Kumar, Gaurav Bhargava   +2 more
exaly  

Antiviral and other bioactivities of pyrimidinones

Pharmacology & Therapeutics, 1985
openaire   +2 more sources

Preparation of 2-pyrimidinone and derivatives

Collection of Czechoslovak Chemical Communications, 1975
V. Uchytilová, A. Holý, D. Cech, J. Gut   +3 more
openaire   +1 more source