Results 41 to 50 of about 2,162 (216)

Shortening the Lipid A Acyl Chains of Bordetella pertussis Enables Depletion of Lipopolysaccharide Endotoxic Activity

Vaccines, 2020
Whooping cough, or pertussis, is an acute respiratory infectious disease caused by the Gram-negative bacterium Bordetella pertussis. Whole-cell vaccines, which were introduced in the fifties of the previous century and proved to be effective, showed ...
Jesús Arenas, Elder Pupo, Coen Phielix, Dionne David, Afshin Zariri, Alla Zamyatina, Jan Tommassen, Peter van der Ley   +7 more
doaj   +1 more source

Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens

Cell Proliferation, EarlyView.
In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu, Bingyu Cai, Tingting Gao, Wumei Wei, Liu Wang, Qi Zhou, Wei Li, Jie Hao, Jun Wu   +8 more
wiley   +1 more source

Update on molecular diversity and multipathogenicity of staphylococcal superantigen toxins

Animal Diseases, 2021
Staphylococcal superantigen (SAg) toxins are the most notable virulence factors associated with Staphylococcus aureus, which is a pathogen associated with serious community and hospital acquired infections in humans and various diseases in animals ...
Dong-Liang Hu, Shaowen Li, Rendong Fang, Hisaya K. Ono   +3 more
doaj   +1 more source

Combined Method to Remove Endotoxins from Protein Nanocages for Drug Delivery Applications: The Case of Human Ferritin

Pharmaceutics, 2021
Protein nanocages represent an emerging candidate among nanoscaled delivery systems. Indeed, they display unique features that proved to be very interesting from the nanotechnological point of view such as uniform structure, stability in biological ...
Filippo Silva, Leopoldo Sitia, Raffaele Allevi, Arianna Bonizzi, Marta Sevieri, Carlo Morasso, Marta Truffi, Fabio Corsi, Serena Mazzucchelli   +8 more
doaj   +1 more source

Effects of Bleaching Protocols on the Esthetic Outcome and Surface Integrity of Enamel Treated With an Ammonia‐Free Silver Fluoride Solution

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To investigate the effects of three bleaching protocols on the color stability and surface roughness of enamel previously treated with a water‐based, ammonia‐free silver fluoride solution (Riva Star Aqua). Materials and Methods Eighty‐eight human enamel/dentin specimens were demineralized and treated with Riva Star Aqua, divided into
Ahmed Alshawi, Fadimeana Lal, Esra Yildiz, Sevda Ozel Yildiz, Ugur Erdemir   +4 more
wiley   +1 more source

Comparative Radiopacity of Additively Manufactured Permanent and Temporary Resins and Conventional Resin‐Based Composites

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective This study aimed to evaluate whether radiopacity differs among additively manufactured permanent resins, temporary resins, and conventional resin‐based composites at clinically relevant thicknesses. Materials and Methods Eight dental materials were evaluated and categorized into four groups: additively manufactured permanent resins ...
Sinem Coşkun‐Albayrak, Ayşenur Öncü, Sedanur Sakalli, Esra Yildirim‐Manav   +3 more
wiley   +1 more source

Sterilized Recombinant Spider Silk Fibers of Low Pyrogenicity

, 2010
We have recently shown that it is possible to recombinantly produce a miniature spider silk protein, 4RepCT, that spontaneously self-assembles into mechanically stable macroscopic fibers (Stark, M.; Grip, S.; Rising, A.; Hedhammar, M.; Engstrom, W ...
Sveriges lantbruksuniversitet., Widhe, Mona,, Hedhammar, My,, Widhe, M., Johansson, J., Askarieh, G., Nordling, Kerstin,, Aulock, Sv, Bramfeldt, Hanna,, Johansson, Jan,, Baris, T., Askarieh, Glareh,, Nordling, K., Bramfeldt, H.   +13 more
core   +1 more source

Bacterial Cellulose Dressings from Mango Pulp Agro-Waste Functionalized with Grapefruit Seed Oil for Diabetic Wound Healing

Polysaccharides
Bacterial cellulose (BC) is an emerging biopolymer for skin tissue regeneration; however, its functionalization with natural antimicrobial agents remains limited.
Mayra E. García-Sánchez, Alfonso Barajas-Cervantes, Inés Jiménez-Palomar, José M. Acosta-Cuevas, Erick O. Cisneros-López   +4 more
doaj   +1 more source

Platonin, a Cyanine Photosensitizing Dye, Inhibits Pyrogen Release and Results in Antipyresis

Journal of Pharmacological Sciences, 2003
: Intravenous injection of the supernatant fluids from human peripheral blood mononuclear cells (PBMC) incubated with lipopolysaccharide (LPS) caused fever in rabbits.
Jie-Jen Lee, Wu-Tein Huang, Dong-Zi Shao, Jyh-Fei Liao, Mao-Tsun Lin   +4 more
doaj   +1 more source

Effect of material, prosthesis height, and aging on the fracture strength of additively and subtractively manufactured implant‐supported cantilevered prostheses

Journal of Prosthodontics, EarlyView.
Abstract Purpose This study aimed to evaluate the inherent and after cyclic loading fracture strength of implant‐supported cantilevered fixed prostheses fabricated from recently introduced additively manufactured (AM) and subtractively manufactured (SM) materials, considering variations in prosthesis height.
Mustafa Borga Dönmez, Paola Maldonado, Çiğdem Kahveci, Ahmet Orgev, Marta Revilla‐León, Burak Yilmaz, Gülce Cakmak   +6 more
wiley   +1 more source