Results 141 to 150 of about 86,176 (262)

The molecular basis of ADP-ribose pyrophosphorylation by a phage PRPS-like enzyme in NAD+ reconstitution. [PDF]

Nucleic Acids Res
Liu M, Ma J, Zhang Q, Xu S, Chen J, Lin E, Wu Y, Li H, Zhou B, Chen L.   +9 more
europepmc   +1 more source

Quantitative Pharmacodynamic Analysis of Trimethoprim‐Sulfonamide Combination Activity Against Staphylococcus pseudintermedius

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Trimethoprim (TMP)‐sulfonamide combinations are widely used in veterinary medicine, yet the quantitative nature of their pharmacodynamic interaction remains incompletely characterised. This study investigated the interaction between TMP and sulfamethoxazole (SMX), sulfadiazine (SDZ) and sulfadimethoxine (SDMX) against two Staphylococcus ...
Andrew Mead, Alexis Viel, Marine Boulanger, Gudrun Overesch, Carl Ekstrand, Pierre‐Louis Toutain, Aude A. Ferran, Ludovic Pelligand   +7 more
wiley   +1 more source

Uridine Bisphosphonate-Carbagalactose: A Stabilized α-1,4-Galactosyltransferase Inhibitor. [PDF]

Org Lett
Guo J, de Koster N, van Puffelen B, Steneker R, Verhoeks V, Ofman TP, Overkleeft HS, Artola M, Filippov DV, Codée JDC.   +9 more
europepmc   +1 more source

Algorithm for Surgical Management in Patients in Treatment With Medication Associated With Osteonecrosis of the Jaws

Oral Surgery, EarlyView.
ABSTRACT Background Osteonecrosis of the jaws is associated with various drugs, including antiresorptives such as bisphosphonates and denosumab, as well as antiangiogenics. These drugs are used for the treatment of multiple diseases, notably osteoporosis, bone metastases, Paget's disease, osteogenesis imperfecta, malignant hypocalcaemia, among others ...
Rodríguez Naranjo Julia Alexandra, Gómez Hernández Kevin Andrew, Cabrera del Cid María Fernanda, Jerez Robalino James Philippe   +3 more
wiley   +1 more source

Donut Morphology of Cardiac Amyloidosis: A Glazed Over Diagnosis. [PDF]

JACC Case Rep
Aggarwal P, Alpert C, Davies D.
europepmc   +1 more source

Artificial Intelligence‐Driven Precision Bisphosphonate Therapy in Osteoporosis: Mechanisms, Clinical Applications, Risks, and Future Directions

Orthopaedic Surgery, EarlyView.
This comprehensive review integrates 17 benchmark studies to illustrate the transition of osteoporosis management toward precision medicine. The schematic highlights three key clinical applications: AI‐driven opportunistic screening from routine CTs, precision pharmacotherapy selection, and the predictive prevention of adverse events like MRONJ ...
Xiang Yao, Yicong Chao, Xiao Gu, Jingtao Peng, Jishan Yuan, Wei Shi, Fuguo Zhang, Qiwen Bao   +7 more
wiley   +1 more source

Snapshot at Saccharomycopsis fibuligera metabolism for industrial terpenoid production and bioengineering. [PDF]

BMC Microbiol
Lopez-Barbera A, Torrell H, Abasolo N, Canela N, Fernández-Arroyo S.   +4 more
europepmc   +1 more source

Metabolic Labeling and Visualization of Isoprenoids Using Alkyne-Modified DMAPP Analogs in Bacillus subtilis. [PDF]

Angew Chem Int Ed Engl
Hulsey ZN, McBee DP, Dolan CL, Rossi FM, Truslow NA, Taylor AR, Trybala TN, Baccile JA.   +7 more
europepmc   +1 more source

Chemical agents to control biofilm formation in step 1 of care—Toothpastes and mouthwashes/concepts and challenges

Periodontology 2000, EarlyView.
Abstract Maintaining optimal oral hygiene is important for overall oral care, ensuring the well‐being of teeth and their surrounding tissues. In addition, it promotes fresh breath and a pleasing smile. A key element of oral self‐care is the daily use of toothpaste during regular brushing.
Maud Joosstens, Cees Valkenburg, Fridus Van der Weijden   +2 more
wiley   +1 more source

Ferric pyrophosphate in precision iron fortification: mechanistic insights into food-system suitability, bioavailability modulation, and evaluation strategies. [PDF]

Food Chem X
Wang Y, Wei Y, Chang M, No J, Liu K.
europepmc   +1 more source