Results 21 to 30 of about 86,176 (262)

Inositol Pyrophosphate Pyrotechnics [PDF]

Cell Metabolism, 2007
Physiologic roles of highly phosphorylated inositol phosphates, including those containing pyrophosphate groups, have been the focus of much recent interest. In the April 6, 2007 issue of Science, two papers (Lee et al., 2007; Mulugu et al., 2007) demonstrate the occurrence of a novel inositol pyrophosphate molecule in yeast and elucidate its role in ...
Bhandari, Rashna, Chakraborty, Anutosh, Snyder, Solomon H.   +2 more
openaire   +2 more sources

Chronic Kidney Disease-Induced Arterial Media Calcification in Rats Prevented by Tissue Non-Specific Alkaline Phosphatase Substrate Supplementation Rather Than Inhibition of the Enzyme

Pharmaceutics, 2021
Patients with chronic kidney disease (CKD) suffer from arterial media calcification and a disturbed bone metabolism. Tissue-nonspecific alkaline phosphatase (TNAP) hydrolyzes the calcification inhibitor pyrophosphate (PPi) into inorganic phosphate (Pi ...
Britt Opdebeeck, Ellen Neven, José Luis Millán, Anthony B. Pinkerton, Patrick C. D’Haese, Anja Verhulst   +5 more
doaj   +1 more source

RETRACTED: Pyrophosphate modulates plant stress responses via SUMOylation

eLife, 2019
Pyrophosphate (PPi), a byproduct of macromolecule biosynthesis is maintained at low levels by soluble inorganic pyrophosphatases (sPPase) found in all eukaryotes. In plants, H+-pumping pyrophosphatases (H+-PPase) convert the substantial energy present in
M Görkem Patir-Nebioglu, Zaida Andrés, Melanie Krebs, Fabian Fink, Katarzyna Drzewicka, Nicolas Stankovic-Valentin, Shoji Segami, Sebastian Schuck, Michael Büttner, Rüdiger Hell, Masayoshi Maeshima, Frauke Melchior, Karin Schumacher   +12 more
doaj   +1 more source

Stabilization of Tc-99m radiopharmaceuticals by chemical additives [PDF]

Journal of the Serbian Chemical Society, 2001
The reliability and applicability of the preparation of the three, for nuclear medicine very important, 99mTc-radiopharmaceuticals from the inactive (technetium-cold) kit solutions were tested.
Vučina Jurij, Vukičević Nadežda
doaj   +1 more source

Stereochemistry at C-1 of geranyl pyrophosphate and neryl pyrophosphate in the cyclization to (+)- and (-)-bornyl pyrophosphate.

Journal of Biological Chemistry, 1985
(1R)-1-3H-labeled and (1S)-1-3H-labeled geranyl pyrophosphate and neryl pyrophosphate were prepared from the corresponding 1-3H-labeled aldehydes by a combination of enzymatic and synthetic procedures. Following admixture with the corresponding 2-14C-labeled internal standard, each substrate was converted to (+)-bornyl pyrophosphate and (-)-bornyl ...
R, Croteau, N M, Felton, C J, Wheeler
openaire   +2 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Oxidative Phosphorus Chemistry Perturbed by Minerals

Life, 2022
Life is a complex, open chemical system that must be supported with energy inputs. If one fathoms how simple early life must have been, the complexity of modern-day life is staggering by comparison. A minimally complex system that could plausibly provide
Arthur Omran, Josh Abbatiello, Tian Feng, Matthew A. Pasek   +3 more
doaj   +1 more source

Biosynthesis of Thiamin Pyrophosphate [PDF]

EcoSal Plus, 2009
The biosynthesis of thiamin pyrophosphate (TPP) in prokaryotes, as represented by the Escherichia coli and the Bacillus subtilis pathways, is summarized in this review. The thiazole heterocycle is formed by the convergence of three separate pathways.
Christopher T, Jurgenson, Steven E, Ealick, Tadhg P, Begley   +2 more
openaire   +2 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

The crystal structure of KScP2O7

Acta Crystallographica Section E: Crystallographic Communications, 2020
Single crystals of KScP2O7, potassium scandium diphosphate, were grown in a borate flux. The title compound crystallizes isotypically with KAlP2O7 in space-group type P21/c, Z = 4.
Günther J. Redhammer, Gerold Tippelt
doaj   +1 more source