Results 191 to 200 of about 82,547 (381)
Pyroptosis regulation by Salmonella effectors
Frontiers in ImmunologyThe genus Salmonella contains the most common foodborne pathogens frequently isolated from food-producing animals and is responsible for zoonotic infections in humans and animals. Salmonella infection in humans and animals can cause intestinal damage, resulting in intestinal inflammation and disruption of intestinal homeostasis more severe cases can ...
Yuan Meng +12 more
openaire +3 more sources
The Fast‐Growing Field of Cancer Immunotherapy Based on Aggregation‐Induced Emission
Aggregate, EarlyView.Photoimmunotherapy facilitated by AIEgens represents an emerging cancer treatment that combines high‐performance phototheranostics with immunotherapy to achieve satisfactory antitumor effectiveness, and has recently been developed at a tremendous pace and attracted global interests in the past few years.
Zhijie Lin +5 more
wiley +1 more source
Translational PsychiatryMelatonin improves chronic stress-induced hippocampal damage and depression-like behaviors, but the mechanism needs further study. This study was to explore the mechanism of melatonin inhibiting microglia pyroptosis.
Zhicheng Gao +6 more
doaj +1 more source
Inhibitory Effects of Ethanol on the NLRP3 Inflammasome [PDF]
, 2015 Immunosuppression is a major complication of alcoholism and contributes to increased rates of opportunistic infections and sepsis associated with the addiction.
Hoyt, Laura Rose
core +1 more source
NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model [PDF]
, 2015 Chen-Chen Tan +11 more
openalex +1 more source
Metabolism‐Regulating Nanomedicines for Cancer Therapy
Advanced NanoBiomed Research, EarlyView.This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source
Gasdermins pore cell membrane to pyroptosis [PDF]
, 2016 Huanhuan Liang, Yingfang Liu
openalex +1 more source
Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy
Advanced NanoBiomed Research, EarlyView.Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li +11 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez +3 more
wiley +1 more source
Lactylation in cancer biology: Unlocking new avenues for research and therapy
Cancer Communications, EarlyView.Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou +6 more
wiley +1 more source