Results 191 to 200 of about 77,046 (386)

Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells

, 2005
Susan L. Fink, Brad T. Cookson
openalex   +1 more source

Gasdermins pore cell membrane to pyroptosis [PDF]

, 2016
Huanhuan Liang, Yingfang Liu
openalex   +1 more source

Differential Regulation of Caspase-1 Activation, Pyroptosis, and Autophagy via Ipaf and ASC in Shigella-Infected Macrophages

, 2007
Toshihiko Suzuki, Luigi Franchi, Claudia Toma, Hiroshi Ashida, Michinaga Ogawa, Yuko Yoshikawa, Hitomi Mimuro, Naohiro Inohara, Chihiro Sasakawa, Gabriel Núñez   +9 more
openalex   +2 more sources

Gout and NLRP3 Inflammasome Biology

Arthritis &Rheumatology, EarlyView.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source

Senkyunolide I Improves Septicemia‐Induced Brain Dysfunction via Regulating Nrf2 and Astrocyte Activity.

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Senkyunolide I (Sen I) has a protective effect on the blood–brain barrier (BBB) in rats with sepsis‐associated encephalopathy (SAE). This study investigated whether Sen I regulates Nrf2 to ameliorate sepsis‐induced brain dysfunction (SIBD). Sixty rats were randomly assigned into Sham group, SAE group (Model group), SAE + Sen I group (72 mg/kg,
Haohao Cao, Tao Liu, Meixia Xu
wiley   +1 more source

Mycobacterium tuberculosis Infection of Dendritic Cells Leads to Partially Caspase-1/11-Independent IL-1β and IL-18 Secretion but Not to Pyroptosis

, 2012
Hana Abdalla, Lalitha Srinivasan, Swati Shah, Katrin D. Mayer-Barber, Alan Sher, Fayyaz S. Sutterwala, Volker Briken   +6 more
openalex   +2 more sources

Development of the Gut Microbial Immune and Epithelial Cellular System (GutMICS) to Investigate the Immunological Role of Gut Anaerobes

Biotechnology and Bioengineering, EarlyView.
Abstract The gut microbiota plays an essential role in host health by regulating gut barrier function and immune system homeostasis. However, research into the physiological and immunological functions of the gut microbiota using In Vitro models that mimic the immune environment of the gut remains limited. Herein, we developed the Gut Microbial Immune &
Seo‐Young Kwon, Sung‐Hyun Jo, Joonha Park, Ji‐Hyeon Park, Ye‐Rim Kim, Ji‐Hyun Baek, Min‐Gyu Kim, Bo‐Gyeong Choi, Na Youn Hong, Hee Kyoung Jung, Hee‐Wook Ryu, Jessie S. Jeon, Yun‐Gon Kim   +12 more
wiley   +1 more source

Caspase-11–mediated endothelial pyroptosis underlies endotoxemia-induced lung injury [PDF]

, 2017
Kwong Tai Cheng, Shiqin Xiong, Zhiming Ye, Zhigang Hong, Anke Di, Kit Man Tsang, Xiaopei Gao, Shejuan An, Manish Mittal, Stephen M. Vogel, Edward A. Miao, Jalees Rehman, Asrar B. Malik   +12 more
openalex   +1 more source

Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis

Nature, 2022
Wanyan Deng, Yang Bai, Fan Deng, Youdong Pan, S. Mei, Zengzhang Zheng, Rui Min, Zeyu Wu, Wu Li, R. Miao, Zhibin Zhang, T. Kupper, J. Lieberman, Xing Liu   +13 more
semanticscholar   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source