Results 301 to 310 of about 82,547 (381)

Correction for McKenzie et al., Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis

, 2019

openalex   +1 more source

Beyond apoptosis: Exploring necroptosis, ferroptosis, and pyroptosis in sevoflurane- and isoflurane-associated PNDs. [PDF]

IBRO Neurosci Rep
Sun H, Cai R, Zhao M, Shan Y, Ma K, Qian M.   +5 more
europepmc   +1 more source

Autophagy in PE: Dispute, Role and Potential Target

Cell Proliferation, EarlyView.
Autophagy homeostasis serves as a central hub regulating vascular remodelling during pregnancy. It integrates maternal, genetic, and fetal factors; shapes the functions of immune cells (NK cells, macrophages, and T cells); restrains endothelial inflammatory responses (cytokines, endothelial cell, oxidative/ER stress, and protein aggregation); and ...
Miao Xu, Qi Wang, Fang Wang, Li Kang, Huijing Ma, Mengnan Li, Zhuanghui Hao, Zhengrui Li, Ji'an Liu, Xufeng Huang, Hengrui Liu, Shouxin Wei, Hailan Yang   +12 more
wiley   +1 more source

Amorphous layered double hydroxide-based nano-enzyme eye drops against dry eye disease by inhibiting mitochondrial damage and pyroptosis. [PDF]

J Nanobiotechnology
Chu D, Hu T, Cui H, Yang L, Li Z, Tan C, Li J.   +6 more
europepmc   +1 more source

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

Cell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao, Hongwei Shi, Di Wu, Rui Liang, Tong Zhao, Wen Sun, Yue Wang, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Haidong Wang, Juan Wang   +12 more
wiley   +1 more source

HIV-1 and SIV Infection are associated with early loss of lung interstitial CD4+ T cells and dissemination of pulmonary tuberculosis [PDF]

, 2019
et al,, Khader, Shabaana A
core   +1 more source

miR-590-3pInhibits Pyroptosis in Diabetic Retinopathy by TargetingNLRP1and Inactivating the NOX4 Signaling Pathway

, 2019
Chufeng Gu, Deji Draga, Chuandi Zhou, Tong Su, Chen Zou, Qing Gu, Tashi Lahm, Zhi Zheng, Qinghua Qiu   +8 more
openalex   +1 more source

Maresin 1 Ameliorates Blue Light Overexposure-Induced Meibomian Gland Dysfunction via Inhibition of NLRP3/Caspase-1/GSDMD-Mediated Pyroptosis. [PDF]

Invest Ophthalmol Vis Sci
Wu M, He HL, Wang C, Wang B, Li YZ, Zhou SR, Cai WY, Xiong N, Zhang MC, Xie HT.   +9 more
europepmc   +1 more source

Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments

The FEBS Journal, EarlyView.
Gasdermins (GSDMs) are pore‐forming proteins best known for driving pyroptosis through plasma membrane (PM) permeabilization. Beyond triggering inflammatory cell death, GSDMs can also associate with organelle membranes, including mitochondria, lysosomes, ER, and nucleus, where they modulate membrane integrity and cellular signaling.
Eleonora Margheritis, Nadine Gehle, Katia Cosentino   +2 more
wiley   +1 more source

A patient‐derived orthotopic xenograft model unveils metastatic dynamics in head and neck squamous cell carcinoma

The FEBS Journal, EarlyView.
Metastasis in head and neck squamous cell carcinoma (HNSC) poses significant clinical challenges. This proof‐of‐concept study establishes patient‐derived orthotopic xenografts (PDOXs) as advanced models that closely replicate primary HNSC tumours, including local lymph node metastasis and the intricate cancer–stroma interaction.
Yuchen Bai, Benjamin Blyth, Jarryd Boath, Qiji Deng, Ruihong Huang, Charbel Darido   +5 more
wiley   +1 more source