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Pyroptosis in health and disease
American Journal of Physiology-Cell PhysiologyThe field of cell death has witnessed significant advancements since the initial discovery of apoptosis in the 1970s. This review delves into the intricacies of pyroptosis, a more recently identified form of regulated, lytic cell death, and explores the roles of pyroptotic effector molecules, with a strong emphasis on their mechanisms and relevance in
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Sheng li xue bao : [Acta physiologica Sinica], 2018
Pyroptosis is a form of inflammatory programmed cell death activated by caspase-1 and caspase-4/5/11, and involves in the pathogenesis of infectious diseases and nervous system diseases. Pyroptosis is mediated by canonical inflammasome pathway and non-canonical inflammasome pathway.
Biao, Tang, Chang-Qing, Deng
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Pyroptosis is a form of inflammatory programmed cell death activated by caspase-1 and caspase-4/5/11, and involves in the pathogenesis of infectious diseases and nervous system diseases. Pyroptosis is mediated by canonical inflammasome pathway and non-canonical inflammasome pathway.
Biao, Tang, Chang-Qing, Deng
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The role of pyroptosis in viral infection
Archives of VirologyPyroptosis, also known as inflammatory necrosis, is a form of programmed cell death, which is an important natural immune response. Pyroptosis plays a major role in combating pathogenic infections. The mechanism of pyroptosis is distinct from other forms of cell death and is characterized by its dependence on inflammatory caspases (mainly caspases 1, 4,
Zhen Zhao, Yan Zhang, Bing Luo
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Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
Cell, 2021Charles L Evavold +2 more
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Molecular mechanisms and functions of pyroptosis in inflammation and antitumor immunity
Molecular Cell, 2021Junwei Hou +2 more
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Prussian Blue Nanozyme as a Pyroptosis Inhibitor Alleviates Neurodegeneration
Advanced Materials, 2022Jianrong Wu, Yuehua Li, Xiaojun Cai
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The Role and Mechanism of Pyroptosis and Potential Therapeutic Targets in Sepsis: A Review
Frontiers in Immunology, 2021Xiangtao Zheng +2 more
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