Results 271 to 280 of about 67,070 (304)
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Inflammasome-independent pyroptosis
Current Opinion in ImmunologyGasdermins are membrane pore-forming proteins that cause pyroptosis, an inflammatory cell death in which cells burst and release cytokines, chemokines, and other host alarm signals, such as ATP and HMGB1, which recruit and activate immune cells at sites of infection and danger. There are five gasdermins in humans - gasdermins A to E.
Xing, Liu, Judy, Lieberman
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PYROPTOSIS and THE MECHANISM OF PYROPTOSIS
2023Hücresel inflamatuar nekrozolarak da bilinen piroptoz, programlanmış hücre ölümünün yeni bir şeklidir. İlkolarak 1992'de Gram negatif bakterilerle enfekte olmuş makrofajlarda tanımlananpiroptozis daha sonra çeşitli bağışıklık hücrelerinde de bildirilmiştir.
Gezer, Arzu, Karadağ Sarı, Ebru
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Assessing Cytoskeletal Destruction During Pyroptosis
2023Pyroptosis is an inflammatory form of cell death driven by the activation of caspase-1 and/or caspase-11 which cleaves and activates the pore-forming and cell-permeabilizing protein gasdermin-D. Pyroptosis is characterized by cell swelling and release of inflammatory cytosolic content, which were thought to be driven by colloid-osmotic lysis.
Michael A, Davis, Michael, Gale
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Poking holes in pyroptosis paradigms
Science Signaling, 2023Several studies show that there is still much to learn about cell death mechanisms.
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Science, 2020
Immunometabolism A form of inflammatory cell death called pyroptosis depends on the caspase-mediated cleavage of gasdermin D (GSDMD), the fragments of which assemble into permeability pores that then kill the cell. The mechanisms regulating this important cellular process are not yet fully understood. Humphries et al.
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Immunometabolism A form of inflammatory cell death called pyroptosis depends on the caspase-mediated cleavage of gasdermin D (GSDMD), the fragments of which assemble into permeability pores that then kill the cell. The mechanisms regulating this important cellular process are not yet fully understood. Humphries et al.
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Pyroptosis mediator identified
Science Signaling, 2015Caspase-mediated cleavage of gasdermin D triggers death by pyroptosis.
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Pyroptosis does damage control
Science SignalingSecreted factors from pyroptotic cells can promote wound repair.
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Ferroptosis and Pyroptosis in Epilepsy
Molecular NeurobiologyEpilepsy is sudden, recurrent, and transient central nervous system dysfunction caused by abnormal discharge of neurons in the brain. Ferroptosis and pyroptosis are newly discovered ways of programmed cell death. One of the characteristics of ferroptosis is the oxidative stress generated by lipid peroxides.
Fan Feng +3 more
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Sheng li xue bao : [Acta physiologica Sinica], 2018
Pyroptosis is a form of inflammatory programmed cell death activated by caspase-1 and caspase-4/5/11, and involves in the pathogenesis of infectious diseases and nervous system diseases. Pyroptosis is mediated by canonical inflammasome pathway and non-canonical inflammasome pathway.
Biao, Tang, Chang-Qing, Deng
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Pyroptosis is a form of inflammatory programmed cell death activated by caspase-1 and caspase-4/5/11, and involves in the pathogenesis of infectious diseases and nervous system diseases. Pyroptosis is mediated by canonical inflammasome pathway and non-canonical inflammasome pathway.
Biao, Tang, Chang-Qing, Deng
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