Results 1 to 10 of about 21,414 (253)
The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice
European Journal of Immunology, 2018 The pro-inflammatory cytokine IL-1β is well known for its role in host defense and the initiation of potent inflammatory responses. It is processed from its inactive pro-form by the inflammatory caspase-1 into its mature bioactive form, which is then ...
Petr Broz +2 more
exaly +2 more sources
Some of the next articles are maybe not open access.
Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis
Immunity, 2018Saumendra N Sarkar +2 more
exaly
Pore-forming activity and structural autoinhibition of the gasdermin family
Nature, 2016Jianjin Shi, Jingjin Ding
exaly
Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
Proceedings of the National Academy of Sciences of the United States of America, 2018Stephen Bunnell +2 more
exaly
Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition
Structure, 2018Tsan Sam Xiao +2 more
exaly
Proceedings of the National Academy of Sciences of the United States of America, 2018
Yinghua Chen +2 more
exaly
Yinghua Chen +2 more
exaly
Intraepithelial mast cells drive gasdermin C-mediated type 2 immunity
ImmunityHuabin He, Xiaoyu Hu, Feng Shao
exaly
Intestinal epithelial Gasdermin C is induced by IL-4R/STAT6 signaling but is dispensable for gut immune homeostasis [PDF]
Scientific ReportsGasdermin C is one of the least studied members of the gasdermin family of proteins, known for their critical involvement in pyroptosis and host defense.
Christoph Becker +2 more
exaly +3 more sources
BMC Biology, 2022 Background Gasdermins are ancient (>500million-years-ago) proteins, constituting a family of pore-forming proteins that allow the release of intracellular content including proinflammatory cytokines.
Diego Angosto-Bazarra +5 more
doaj +2 more sources