Results 151 to 160 of about 132,748 (328)
Chemistry – A European Journal, EarlyView.A straightforward one‐step protocol enables the synthesis of bio‐based and biologically active isochromans through the Oxa‐Pictet cyclization involving diverse aldehydes, including vanillin in combination with lignin‐derivable homovanillyl alcohol, a prominent aromatic platform chemical obtainable via diol‐assisted fractionation of lignocellulose ...
Anjali Kottayi +6 more
wiley +1 more source
Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy
Chemistry – A European Journal, EarlyView.Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez +3 more
wiley +1 more source
Diversity and conservation of interactions for binding heme in b-type heme proteins [PDF]
, 2007 Marles-Wright, Jon +3 more
core +1 more source
Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis
Chemistry – A European Journal, EarlyView.We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley +1 more source
Porphyrin‐Geländer–Helical Conjugated Banister Type Porphyrin Dyads
Chemistry – A European Journal, EarlyView.Porphyrin arrays go chiral–A porphyrin Geländer macrocycle represents the intriguing prototype architecture of helically chiral butadiyne‐linked porphyrin arrays. This study combines synthetic, spectroscopic, and computational methods to shed light on its structure, chiroptical properties, and tunability, highlighting its promise for advancing ...
Joël F. Keller +2 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley +1 more source
Chemistry – A European Journal, EarlyView.We report an efficient method for late‐stage installation of “clickable” alkyne groups into diverse (hetero)arenes. Using a dual‐ligand palladium catalyst that combines an NASA ligand with an N‐heterocycle, an acrylate unit bearing a terminal alkyne can be introduced via nondirected C─H activation.
Tommaso Braga +2 more
wiley +1 more source
Generation of a Ground‐State Electron Donor Utilizing Stored Light Energy
Chemistry – A European Journal, EarlyView.Chemically stored light energy enables the generation of dianion reductants (∼−2.7 V) from vicinal diols derived from diaryl ketone photodimerization. These ground‐state electron donors efficiently reduce challenging substrates at room temperature, including aryl bromides, alkyl iodides, and sulfonamides.
Marc Taillefer +2 more
wiley +1 more source