Results 11 to 20 of about 132,748 (328)

Bioactive pyrrole-based compounds with target selectivity

European journal of medicinal chemistry, 2020
The discovery of novel synthetic compounds with drug-like properties is an ongoing challenge in medicinal chemistry. Natural products have inspired the synthesis of compounds for pharmaceutical application, most of which are based on N-heterocyclic ...
Giovanna Li Petri, V. Spanò, Roberto Spatola, Ralph Holl, M. V. Raimondi, P. Barraja, A. Montalbano   +6 more
semanticscholar   +1 more source

Pyrrole-Pyridine and Pyrrole-Naphthyridine Hosts for Anion Recognition [PDF]

Molecules, 2015
The association constants of the complexes formed by two hosts containing pyrrole, amide and azine (pyridine and 1,8-naphthyridine) groups and six guests, all monoanions (Cl−, CH3CO2−, NO3−, H2PO4−, BF4−, PF6−), have been determined using NMR titrations.
M. García, M. Farrán, Dolores María, Rosa Claramunt, M. Torralba, M. Torres, Carlos Jaime, José Elguero   +7 more
openaire   +9 more sources

蛋白质吡咯加合物与血糖指数升高和糖尿病弥漫性神经病的临床特征相关

Journal of Diabetes, 2022
Introduction Diabetic neuropathy is the most prevalent complication of diabetes mellitus. Although the precise etiology of this neurological disorder has yet to be defined, elevated blood glucose promotes anerobic glycolysis; this produces excess ...
Xiao Chen, Zhuyi Jiang, Lianjing Zhang, Wei Liu, Xiaohu Ren, Luling Nie, Desheng Wu, Zhiwei Guo, Weimin Liu, Xifei Yang, Yan Wu, Zhen Liang, Peter Spencer, Jianjun Liu   +13 more
doaj   +1 more source

In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography [PDF]

, 2008
The biodistribution profiles in mice of two pyrrole-imidazole polyamides were determined by PET. Pyrrole-imidazole polyamides are a class of small molecules that can be programmed to bind a broad repertoire of DNA sequences, disrupt transcription factor ...
Bergstr  m, Burns, Chou, D. A. Harki, D. B. Stout, Dervan, Dervan, Dudouet, Edelson, Gross, Harapanhalli, Hsu, K  hnast, Lee, Lendvai, M. E. Phelps, N. Satyamurthy, P. B. Dervan, Phelps, Phelps, Poethko, Puckett, Roivainen, Schottelius, Tavitian, Toyokuni, Trauger   +26 more
core   +3 more sources

2-[(1H-Pyrrol-2-yl)methyl]-1H-pyrrole [PDF]

Acta Crystallographica Section E Structure Reports Online, 2013
In the title compound, C9H10N2, the two pyrrole ring planes are twisted by a dihedral angle of 69.07 (16)° and the C—C—C methane angle is 115.1 (2)°. In the crystal, molecules are connected into layers in thebcplane by N—H...π interactions.
Chong-Hyeak Kim, Yea-Sel Jeon, Vincent Lynch, Jonathan L. Sessler, Kwang-Jin Hwang   +4 more
openaire   +3 more sources

Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part 1: Five-Membered Aromatic Rings with One Heteroatom

Molecules, 2021
This review gives an up-to-date overview of the different ways (routes) to the synthesis of coumarin(benzopyrone)-fused, five-membered aromatic heterocycles with one heteroatom, built on the pyrone moiety. Covering 1966 to 2020.
Eslam Reda El-Sawy, Ahmed Bakr Abdelwahab, Gilbert Kirsch   +2 more
doaj   +1 more source

Basic properties of potassium oxide supported on zeolite y studied by pyrrole-tpd and catalytic conversion of methylbutynol

Química Nova, 2012
We report on the basic properties of zeolite NaY and potassium supported on NaY (K/NaY) assessed by pyrrole-TPD and MBOH transformation. Pyrrole-TPD revealed that impregnation of zeolite NaY with potassium promoted additional adsorption sites for pyrrole
Supamathanon Nuttinee, Wittayakun Jatuporn, Prayoonpokarach Sanchai, Supronowicz Wojciech, Roessner Frank   +4 more
doaj   +1 more source

The Synthesis and Properties of Ladder-Type π-Conjugated Compounds with Pyrrole and Phosphole Rings

Molecules, 2023
The phosphole ring is known as a useful building block for constructing π-conjugated organic materials. Here, we report ladder-type benzophospholo[3,2-b]indole (BPI) derivatives where the phosphole and the pyrrole rings are directly fused.
Minh Anh Truong, Suzuho Morishita, Keiichi Noguchi, Koji Nakano   +3 more
doaj   +1 more source

Development of a Molecular-Imprinted-Polymer based sensor for the electrochemical determination of Triacetone Triperoxide (TATP) [PDF]

, 2014
.The explosive triacetone triperoxide (TATP), which can be prepared from commercially readily available reagents following an easy synthetic procedure, is one of the most common components of improvised explosive devices (IEDs).
Ansari, Belluck, Burks, Buttigieg, Jose Gonzalez-Rodriguez, Kende, Laine, Li, Lin, Lubczyk, Lubczyk, Oxley, Riskin, Samuel Mamo, Schulte-Ladbeck, Sharma, Walter, Widmer, Xie, Yan   +19 more
core   +2 more sources

Synthesis, Hydrolytic Stability and In Vivo Biological Study of Bioconjugates of the Tetrapeptides FELL Containing Pyrrole Moiety

Biomedicines, 2023
Background: Bioconjugates are promising alternatives for the multiple targeting of any disease. Pyrrole heterocycle is well known with many activities and is a building block of a lot of medical drugs. On the other hand, peptides are short molecules with
Boryana Borisova, Stanislava Vladimirova, Hristina Nocheva, Marie Laronze-Cochard, Stéphane Gérard, Stoyko Petrin, Dancho Danalev   +6 more
doaj   +1 more source