Results 221 to 230 of about 17,074 (296)

Shape-Conserving Atom Replacements. [PDF]

Chem Rev
Puriņš M, Elgindy C, Levin MD.
europepmc   +1 more source

Unusual backfolded binding poses of BAZ2A bromodomain binders

Acta Crystallographica Section D, EarlyView.
We identified BAZ2A‐binding compounds assuming a peculiar, almost enclosed, conformation. These molecules pose a basis for the development of potent BAZ2A macrocyclic inhibitors, as performed for other bromodomains.BAZ2A is a large multidomain protein overexpressed in aggressive prostate cancer, where it potentiates migration and invasion of other ...
Andrea Dalle Vedove, Giulia Cazzanelli, Vito Giuseppe D'Agostino, Pablo Andres Vargas Rosales, Amedeo Caflisch, Graziano Lolli   +5 more
wiley   +1 more source

A preliminary model to establish a digital twin for coffee roasting. [PDF]

Sci Rep
Bruno MJ, Egidi N, Fatone L, Giacomini J, Maponi P, Sagratini G, Santanatoglia A, Trebović E.   +7 more
europepmc   +1 more source

Mechanistic insights into HapC: A key enzyme in prodiginine biosynthesis in Hahella chejuensis

The FEBS Journal, EarlyView.
HapC catalyzes prodiginine biosynthesis through coordinated movements of its ATP‐binding, substrate‐binding, and catalytic‐swivel domains. The enzyme shows tolerance toward short‐chain MAP analogs, and docking analyses reveal key residues and structural features underlying its substrate flexibility.
Yueh‐Te Chan, Aden Dhana Rizkita, Hsin‐Ju Hsieh, Shu‐Fang Hsu, Tony Eight Lin, Wei‐Jan Huang, Kai‐Cheng Hsu, Sheila Nathan, Peiching Chang, Andrew H.‐J. Wang, Cheng‐Chung Lee   +10 more
wiley   +1 more source

Electrochemical cyclization of alkynes to construct five-membered nitrogen-heterocyclic rings. [PDF]

Beilstein J Org Chem
Peng L, Wang T, Yuan Z, Li B, Tang Z, Liu X, Li H, Jiang G, Zeng C, Wong HNC, Peng XS.   +10 more
europepmc   +1 more source

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

International Journal of Cosmetic Science, EarlyView.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh, Lucília da P. da Silva, Carlos A. Pinto, Rosário Martins, Alexandra P. Marques, Jorge A. Saraiva   +5 more
wiley   +1 more source

Synthesis and Optical Properties of Unsymmetric Aromatically π-Extended BODIPY. [PDF]

J Org Chem
Dvoracek M, Newman C, Drobizhev M, Twamley B, Senge MO, Vinogradov SA, Filatov MA.   +6 more
europepmc   +1 more source

Ingestion of attractive toxic sugar baits containing ivermectin before and after blood feeding affects the biology and reproduction of Aedes aegypti (Diptera: Culicidae)

Medical and Veterinary Entomology, EarlyView.
Attractive toxic sugar bait containing ivermectin (ATSB‐IVM) ingestion markedly reduced blood feeding, survival, oviposition, egg production and larval hatching, with the strongest effects when baits were ingested before blood feeding. Timing of ingestion (48–96 h before or after blood feeding) shaped sublethal impacts across the first and second ...
Thais Alves de Moura, Alyne Cunha Alves Dias, Alexandre de Almeida e Silva   +2 more
wiley   +1 more source

Molecular Editing of 5-Alkynyl-1,2,3-triazines via a Silver-Mediated Skeletal Remodeling Approach: Solvent-Controlled Switchable Synthesis of Functionalized Pyrroles and Furans. [PDF]

J Org Chem
Chen HW, Liu WH, Chang CH, Shie JJ.
europepmc   +1 more source

Indoor residual spraying of distinct insecticide formulations in a household‐scale micro‐mosaic format: Feasibility and effectiveness for malaria vector control in rural Zambia

Medical and Veterinary Entomology, EarlyView.
Densities of all Anopheles species were approximately comparable across all IRS regimes. No differences observed between treatment regimes regarding species composition of the Anopheles funestus group or An. gambiae complex. This operational pilot demonstrates the practical feasibility of IRS micro‐mosaics, despite the inherent increase in deployment ...
Dingani Chinula, Kenzo Mumba, Reuben Zulu, Ketty Ndhlovu, Deogratius R. Kavishe, Neil Philip Hobbs, Samson Kiware, Thomas Reed, Busiku Hamainza, Gerry F. Killeen   +9 more
wiley   +1 more source